AU2745497A - Compositions for use in embolizing blood vessels - Google Patents
Compositions for use in embolizing blood vesselsInfo
- Publication number
- AU2745497A AU2745497A AU27454/97A AU2745497A AU2745497A AU 2745497 A AU2745497 A AU 2745497A AU 27454/97 A AU27454/97 A AU 27454/97A AU 2745497 A AU2745497 A AU 2745497A AU 2745497 A AU2745497 A AU 2745497A
- Authority
- AU
- Australia
- Prior art keywords
- compositions
- blood vessels
- embolizing blood
- copolymers
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000004204 blood vessel Anatomy 0.000 title abstract 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000020 Nitrocellulose Substances 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 229920006217 cellulose acetate butyrate Polymers 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- 239000011976 maleic acid Substances 0.000 abstract 1
- 229920001220 nitrocellulos Polymers 0.000 abstract 1
- 229920002239 polyacrylonitrile Polymers 0.000 abstract 1
- 229920002635 polyurethane Polymers 0.000 abstract 1
- 239000004814 polyurethane Substances 0.000 abstract 1
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 1
- 239000011118 polyvinyl acetate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a polymer, a biocompatible solvent and a contrast agent. The polymer is selected from the group consisting of polyacrylonitrile, polyurethane, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65582296A | 1996-05-31 | 1996-05-31 | |
| US08655822 | 1996-05-31 | ||
| US80225297A | 1997-02-19 | 1997-02-19 | |
| US08802252 | 1997-02-19 | ||
| PCT/US1997/007055 WO1997045131A1 (en) | 1996-05-31 | 1997-04-25 | Compositions for use in embolizing blood vessels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2745497A true AU2745497A (en) | 1998-01-05 |
Family
ID=27097047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU27454/97A Abandoned AU2745497A (en) | 1996-05-31 | 1997-04-25 | Compositions for use in embolizing blood vessels |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US6342202B1 (en) |
| EP (1) | EP0928195B1 (en) |
| JP (1) | JP2001509133A (en) |
| AT (1) | ATE230269T1 (en) |
| AU (1) | AU2745497A (en) |
| CA (1) | CA2252718A1 (en) |
| DE (1) | DE69718180T2 (en) |
| WO (1) | WO1997045131A1 (en) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE230269T1 (en) * | 1996-05-31 | 2003-01-15 | Micro Therapeutics Inc | COMPOSITIONS FOR USE IN EMBOLIZING BLOOD VESSELS |
| US7063532B1 (en) | 1997-06-20 | 2006-06-20 | Align Technology, Inc. | Subdividing a digital dentition model |
| US6569417B2 (en) * | 1997-10-10 | 2003-05-27 | Micro Therapeutics, Inc. | Methods for treating urinary incontinence in mammals |
| US6146373A (en) * | 1997-10-17 | 2000-11-14 | Micro Therapeutics, Inc. | Catheter system and method for injection of a liquid embolic composition and a solidification agent |
| US6511468B1 (en) | 1997-10-17 | 2003-01-28 | Micro Therapeutics, Inc. | Device and method for controlling injection of liquid embolic composition |
| US6015541A (en) * | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
| US6059766A (en) | 1998-02-27 | 2000-05-09 | Micro Therapeutics, Inc. | Gynecologic embolotherapy methods |
| US6113629A (en) * | 1998-05-01 | 2000-09-05 | Micrus Corporation | Hydrogel for the therapeutic treatment of aneurysms |
| CN1230131C (en) * | 1998-11-13 | 2005-12-07 | 生物相容英国有限公司 | Therapeutic use of polymers |
| US6595910B2 (en) | 1998-12-11 | 2003-07-22 | Scimed Life Systems, Inc. | Method for treating fecal incontinence |
| US6251064B1 (en) | 1998-12-11 | 2001-06-26 | Enteric Medical Technologies, Inc. | Method for creating valve-like mechanism in natural body passageway |
| US7132582B2 (en) | 2003-05-30 | 2006-11-07 | Council Of Scientific And Industrial Research | Catalytic process for the preparation of isolongifolene |
| ES2252998T3 (en) * | 1998-12-11 | 2006-05-16 | Boston Scientific Limited | DIGESTIVE TUBE TREATMENT AND KIT FOR IT. |
| US6238335B1 (en) | 1998-12-11 | 2001-05-29 | Enteric Medical Technologies, Inc. | Method for treating gastroesophageal reflux disease and apparatus for use therewith |
| AU6058000A (en) * | 1999-07-12 | 2001-01-30 | Scimed Life Systems, Inc. | Liquid based vaso-occlusive compositions |
| US6358197B1 (en) | 1999-08-13 | 2002-03-19 | Enteric Medical Technologies, Inc. | Apparatus for forming implants in gastrointestinal tract and kit for use therewith |
| US6540789B1 (en) | 2000-06-15 | 2003-04-01 | Scimed Life Systems, Inc. | Method for treating morbid obesity |
| US6855154B2 (en) | 2000-08-11 | 2005-02-15 | University Of Louisville Research Foundation, Inc. | Endovascular aneurysm treatment device and method |
| US7294137B2 (en) * | 2001-03-27 | 2007-11-13 | Boston Scientific Scimed | Device for multi-modal treatment of vascular lesions |
| US20030004533A1 (en) * | 2001-05-04 | 2003-01-02 | Concentric Medical | Bioactive polymer vaso-occlusive device |
| US7687053B2 (en) * | 2001-08-20 | 2010-03-30 | Boston Scientific Scimed, Inc. | Embolic compositions with non-cyanoacrylate rheology modifying agents |
| DK1380263T3 (en) * | 2002-07-12 | 2007-12-27 | Mycrona Ges Fuer Innovative Me | Method and apparatus for determining the actual position of a survey object |
| WO2004028569A1 (en) * | 2002-09-25 | 2004-04-08 | Biocompatibles Uk Limited | Polymer compositions for administration to animals |
| WO2004035022A2 (en) * | 2002-10-15 | 2004-04-29 | Microtherapeutics, Inc. | Prepolymeric materials for site specific delivery to the body |
| AU2003295963B2 (en) | 2002-11-25 | 2009-09-03 | Boston Scientific Limited | Injection device for treating mammalian body |
| US20040161466A1 (en) | 2003-02-14 | 2004-08-19 | Biocompatibles Uk Limited | Chemoembolisation |
| CA2510678A1 (en) * | 2003-03-07 | 2004-09-23 | Microtherapeutics, Inc. | Compositions for use in embolizing blood vessels comprising high levels of contrast agent |
| US7651513B2 (en) * | 2003-04-03 | 2010-01-26 | Boston Scientific Scimed, Inc. | Flexible embolic device delivery system |
| US8048407B2 (en) * | 2003-04-24 | 2011-11-01 | Brent Vernon | In situ gelling self-reactive materials for embolization |
| AU2004275878B2 (en) | 2003-09-25 | 2011-04-14 | Rutgers, The State University | Inherently radiopaque polymeric products for embolotherapy |
| US20050090804A1 (en) * | 2003-10-22 | 2005-04-28 | Trivascular, Inc. | Endoluminal prosthesis endoleak management |
| WO2005067990A1 (en) * | 2004-01-07 | 2005-07-28 | Boston Scientific Santa Rosa Corporation | Methods, compositions, and devices for embolizing body lumens |
| BRPI0502442B1 (en) * | 2004-06-28 | 2015-09-08 | Degudent Gmbh | opaque dental ceramics, and its preparation process |
| US8814567B2 (en) * | 2005-05-26 | 2014-08-26 | Zimmer Dental, Inc. | Dental implant prosthetic device with improved osseointegration and esthetic features |
| US8377091B2 (en) | 2006-06-15 | 2013-02-19 | Microvention, Inc. | Embolization device constructed from expansile polymer |
| WO2008023388A1 (en) | 2006-08-23 | 2008-02-28 | Budhaditya Chattopadhyay | An apparatus for purificatiion of blood and a process thereof |
| US8262626B2 (en) | 2007-10-23 | 2012-09-11 | Boston Scientific Scimed, Inc. | Apparatus and method for treating tissue |
| AU2008345590B2 (en) | 2007-12-21 | 2014-10-30 | Microvention, Inc. | Hydrogel filaments for biomedical uses |
| CN102015012A (en) * | 2008-02-29 | 2011-04-13 | 普拉罗美德公司 | Local embolization by heating thermosensitive polymers |
| EP2254651A4 (en) * | 2008-02-29 | 2013-03-06 | Pluromed Inc | Local embolization using thermosensitive polymers |
| EP2268290B1 (en) * | 2008-03-11 | 2013-01-30 | Sujoy Kumar Guha | Styrene maleic anhydride based formulation for male contraception and prostate cancer |
| US9107668B2 (en) * | 2008-03-25 | 2015-08-18 | Cook Medical Technologies Llc | Embolic particle mixing syringe |
| US8562348B2 (en) * | 2008-07-02 | 2013-10-22 | Zimmer Dental, Inc. | Modular implant with secured porous portion |
| CN102186526B (en) | 2008-08-19 | 2013-10-30 | 泰科保健集团有限合伙公司 | Detachable tip microcatheter |
| US20100114314A1 (en) * | 2008-11-06 | 2010-05-06 | Matthew Lomicka | Expandable bone implant |
| EP2424775B1 (en) | 2009-04-30 | 2016-02-10 | Technip France | Spar mooring line sharing method and system |
| US9707058B2 (en) | 2009-07-10 | 2017-07-18 | Zimmer Dental, Inc. | Patient-specific implants with improved osseointegration |
| US9993252B2 (en) | 2009-10-26 | 2018-06-12 | Microvention, Inc. | Embolization device constructed from expansile polymer |
| US10398444B2 (en) | 2011-03-30 | 2019-09-03 | Noha, Llc | Advanced endovascular clip and method of using same |
| US10028745B2 (en) | 2011-03-30 | 2018-07-24 | Noha, Llc | Advanced endovascular clip and method of using same |
| US9456823B2 (en) | 2011-04-18 | 2016-10-04 | Terumo Corporation | Embolic devices |
| US9011884B2 (en) | 2012-04-18 | 2015-04-21 | Microvention, Inc. | Embolic devices |
| JP6480327B2 (en) | 2012-06-14 | 2019-03-06 | マイクロベンション インコーポレイテッドMicrovention, Inc. | Polymer therapeutic composition |
| US10124087B2 (en) | 2012-06-19 | 2018-11-13 | Covidien Lp | Detachable coupling for catheter |
| JP6385937B2 (en) | 2012-10-15 | 2018-09-05 | マイクロベンション インコーポレイテッドMicrovention, Inc. | Polymeric therapeutic composition |
| CN116333348A (en) * | 2013-10-17 | 2023-06-27 | 伊莱恩·莱斯纳 | Compositions and methods involving occlusive polymer hydrogels |
| US10124090B2 (en) | 2014-04-03 | 2018-11-13 | Terumo Corporation | Embolic devices |
| JP6599361B2 (en) | 2014-04-29 | 2019-10-30 | マイクロベンション インコーポレイテッド | Polymer containing an active agent |
| WO2015167751A1 (en) | 2014-04-29 | 2015-11-05 | Microvention, Inc. | Polymers |
| JP6149871B2 (en) * | 2015-01-15 | 2017-06-21 | 日本精工株式会社 | Bearing with wireless sensor |
| WO2016201250A1 (en) | 2015-06-11 | 2016-12-15 | Microvention, Inc. | Expansile device for implantation |
| WO2017083753A1 (en) | 2015-11-12 | 2017-05-18 | Herr John C | Compositions and methods for vas-occlusive contraception and reversal thereof |
| US10368874B2 (en) | 2016-08-26 | 2019-08-06 | Microvention, Inc. | Embolic compositions |
| US12383421B2 (en) | 2017-01-05 | 2025-08-12 | Contraline, Inc. | Contraceptive devices |
| CN110381854A (en) | 2017-01-05 | 2019-10-25 | 考恩特兰有限公司 | Methods for implanting and reversing stimulus-responsive implants |
| WO2018183624A1 (en) | 2017-03-29 | 2018-10-04 | The Regents Of The University Of Colorado, A Body Corporate | Reverse thermal gels and their use as vascular embolic repair agents |
| JP7362598B2 (en) | 2017-10-09 | 2023-10-17 | マイクロベンション インコーポレイテッド | radioactive liquid embolic material |
| WO2020102234A1 (en) | 2018-11-13 | 2020-05-22 | Contraline, Inc. | Systems and methods for delivering biomaterials |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3527224A (en) | 1967-09-05 | 1970-09-08 | American Cyanamid Co | Method of surgically bonding tissue together |
| US3591676A (en) | 1968-11-01 | 1971-07-06 | Eastman Kodak Co | Surgical adhesive compositions |
| US4078124A (en) * | 1969-10-09 | 1978-03-07 | Exxon Research & Engineering Co. | Laminated non-woven sheet |
| US4079124A (en) | 1976-04-21 | 1978-03-14 | Medi-Physics, Inc. | Method of preparing X-ray contrast media containing ores of hafnium, tantalum and tungsten |
| CA1225585A (en) * | 1983-06-30 | 1987-08-18 | Maria T. Litvinova | Composition for embolization of blood vessels |
| US4631188A (en) | 1983-08-31 | 1986-12-23 | S.K.Y. Polymers, Ltd. (Kingston Technologies) | Injectable physiologically-acceptable polymeric composition |
| EP0153407B1 (en) * | 1983-08-31 | 1993-03-03 | S.K.Y. Polymers Ltd. | Injectable physiologically acceptable polymeric compositions |
| US4847065A (en) * | 1987-02-10 | 1989-07-11 | Akimova Alla Y | Composition for occlusion of ducts and cavities of human body |
| US4795741A (en) | 1987-05-06 | 1989-01-03 | Biomatrix, Inc. | Compositions for therapeutic percutaneous embolization and the use thereof |
| DE3717871C3 (en) * | 1987-05-27 | 1995-05-04 | Georg Prof Dr Schloendorff | Method and device for reproducible visual representation of a surgical intervention |
| JPH02503519A (en) * | 1987-05-27 | 1990-10-25 | サージカル ナビゲーション テクノロジース インコーポレーティッド(アン アフィリエイティッド カンパニー オブ ソファマー ダンネク グループ インコーポレーティッド) | Method and apparatus for reproducibly optically displaying surgical procedures |
| US5213788A (en) * | 1988-09-29 | 1993-05-25 | Ranney David F | Physically and chemically stabilized polyatomic clusters for magnetic resonance image and spectral enhancement |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US4938961A (en) * | 1989-04-28 | 1990-07-03 | Geoffrey Collins | Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia |
| JPH03252799A (en) | 1990-03-01 | 1991-11-12 | Kajima Corp | Illegal parking/stopping managing device |
| JPH0455273A (en) | 1990-06-22 | 1992-02-21 | Mitsubishi Electric Corp | elevator control device |
| DE69114782T2 (en) | 1990-08-08 | 1996-04-18 | Takeda Chemical Industries Ltd | Intravascular embolizing agent containing an angiogenesis inhibitor. |
| GB9026588D0 (en) | 1990-12-06 | 1991-04-24 | Marconi Gec Ltd | Improvements relating to optical sensing systems |
| JP2736339B2 (en) | 1992-09-30 | 1998-04-02 | 株式会社日本感光色素研究所 | Liquid embolic material for aneurysms |
| US5443454A (en) | 1992-12-09 | 1995-08-22 | Terumo Kabushiki Kaisha | Catheter for embolectomy |
| JP2535785B2 (en) * | 1994-06-03 | 1996-09-18 | 工業技術院長 | Vascular embolic agent |
| US5580568A (en) | 1995-07-27 | 1996-12-03 | Micro Therapeutics, Inc. | Cellulose diacetate compositions for use in embolizing blood vessels |
| US5667767A (en) | 1995-07-27 | 1997-09-16 | Micro Therapeutics, Inc. | Compositions for use in embolizing blood vessels |
| ES2194110T3 (en) * | 1995-07-27 | 2003-11-16 | Micro Therapeutics Inc | NEW EMBOLIZING COMPOSITIONS. |
| US5702361A (en) * | 1996-01-31 | 1997-12-30 | Micro Therapeutics, Inc. | Method for embolizing blood vessels |
| US6103254A (en) * | 1996-05-31 | 2000-08-15 | Micro Therapeutics, Inc. | Methods for sterilizing male mammals |
| ATE230269T1 (en) | 1996-05-31 | 2003-01-15 | Micro Therapeutics Inc | COMPOSITIONS FOR USE IN EMBOLIZING BLOOD VESSELS |
| US5695480A (en) | 1996-07-29 | 1997-12-09 | Micro Therapeutics, Inc. | Embolizing compositions |
| DE69835422T2 (en) * | 1998-01-22 | 2006-12-21 | Biosense Webster, Inc., Diamond Bar | MEASUREMENT IN THE BODY'S INSIDE |
| JP3252799B2 (en) | 1998-06-25 | 2002-02-04 | 日本電気株式会社 | Input power control circuit |
| US6531111B1 (en) * | 1999-05-21 | 2003-03-11 | Micro Therapeutics, Inc. | High viscosity embolizing compositions |
-
1997
- 1997-04-25 AT AT97921412T patent/ATE230269T1/en active
- 1997-04-25 CA CA002252718A patent/CA2252718A1/en not_active Abandoned
- 1997-04-25 AU AU27454/97A patent/AU2745497A/en not_active Abandoned
- 1997-04-25 WO PCT/US1997/007055 patent/WO1997045131A1/en not_active Ceased
- 1997-04-25 EP EP97921412A patent/EP0928195B1/en not_active Expired - Lifetime
- 1997-04-25 DE DE69718180T patent/DE69718180T2/en not_active Expired - Lifetime
- 1997-04-25 JP JP54238697A patent/JP2001509133A/en active Pending
- 1997-08-27 US US08/917,721 patent/US6342202B1/en not_active Expired - Lifetime
-
2001
- 2001-05-04 US US09/848,312 patent/US20010024637A1/en not_active Abandoned
- 2001-12-26 US US10/025,791 patent/US6756031B2/en not_active Expired - Lifetime
-
2002
- 2002-06-05 US US10/161,606 patent/US7138106B2/en not_active Expired - Fee Related
- 2002-08-20 US US10/223,438 patent/US20030003056A1/en not_active Abandoned
-
2003
- 2003-03-24 US US10/394,231 patent/US6858219B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030185758A1 (en) | 2003-10-02 |
| US6342202B1 (en) | 2002-01-29 |
| US20030003056A1 (en) | 2003-01-02 |
| EP0928195B1 (en) | 2003-01-02 |
| US6858219B2 (en) | 2005-02-22 |
| DE69718180D1 (en) | 2003-02-06 |
| US20010024637A1 (en) | 2001-09-27 |
| US7138106B2 (en) | 2006-11-21 |
| DE69718180T2 (en) | 2003-08-21 |
| EP0928195A1 (en) | 1999-07-14 |
| US20020076381A1 (en) | 2002-06-20 |
| US6756031B2 (en) | 2004-06-29 |
| US20020187102A1 (en) | 2002-12-12 |
| WO1997045131A1 (en) | 1997-12-04 |
| ATE230269T1 (en) | 2003-01-15 |
| JP2001509133A (en) | 2001-07-10 |
| CA2252718A1 (en) | 1997-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |