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AU2629599A - Purification of tramadol - Google Patents

Purification of tramadol

Info

Publication number
AU2629599A
AU2629599A AU26295/99A AU2629599A AU2629599A AU 2629599 A AU2629599 A AU 2629599A AU 26295/99 A AU26295/99 A AU 26295/99A AU 2629599 A AU2629599 A AU 2629599A AU 2629599 A AU2629599 A AU 2629599A
Authority
AU
Australia
Prior art keywords
tramadol
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU26295/99A
Inventor
Nicholas Archer
Brent Hurley
Melville Mitchell
Helen Ogden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Macfarlan Smith Ltd
Original Assignee
Macfarlan Smith Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macfarlan Smith Ltd filed Critical Macfarlan Smith Ltd
Publication of AU2629599A publication Critical patent/AU2629599A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU26295/99A 1998-01-14 1999-01-14 Purification of tramadol Withdrawn AU2629599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9800657.0A GB9800657D0 (en) 1998-01-14 1998-01-14 Improved purification process
GB9800657 1998-01-14
PCT/GB1999/000012 WO1999036389A1 (en) 1998-01-14 1999-01-14 Purification of tramadol

Publications (1)

Publication Number Publication Date
AU2629599A true AU2629599A (en) 1999-08-02

Family

ID=10825210

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26295/99A Withdrawn AU2629599A (en) 1998-01-14 1999-01-14 Purification of tramadol

Country Status (3)

Country Link
AU (1) AU2629599A (en)
GB (1) GB9800657D0 (en)
WO (1) WO1999036389A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20014669A3 (en) * 1999-06-22 2002-05-15 Grünenthal GmbH Method for separating the diastereomer bases of 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-cyclohexanol
KR100342919B1 (en) * 1999-10-21 2002-07-04 박노중 A preparation and purification for trans isomer of tramadol hydrochloride
US6649783B2 (en) 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
EP1785412A1 (en) 2005-11-14 2007-05-16 IPCA Laboratories Limited Tramadol recovery process

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
IL103096A (en) * 1992-09-08 1996-12-05 Chemagis Ltd Process for the purification of 2-[(dimethyllamino)methyl]-1-(3-methoxyphenyl) cyclohexanol and its salts
CN1151122C (en) * 1997-07-15 2004-05-26 拉辛斯基有限公司 Tramadol and its salts and their preparation methods

Also Published As

Publication number Publication date
GB9800657D0 (en) 1998-03-11
WO1999036389A1 (en) 1999-07-22

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