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AU2620388A - Imidazo(1,2-a)(pyridazines or pyrazines) for treatment of diseases related to bone loss - Google Patents

Imidazo(1,2-a)(pyridazines or pyrazines) for treatment of diseases related to bone loss

Info

Publication number
AU2620388A
AU2620388A AU26203/88A AU2620388A AU2620388A AU 2620388 A AU2620388 A AU 2620388A AU 26203/88 A AU26203/88 A AU 26203/88A AU 2620388 A AU2620388 A AU 2620388A AU 2620388 A AU2620388 A AU 2620388A
Authority
AU
Australia
Prior art keywords
pyridazines
pyrazines
imidazo
treatment
bone loss
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU26203/88A
Inventor
Ingemar Starke
Kalervo Vaananen
Bjorn Wallmark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of AU2620388A publication Critical patent/AU2620388A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU26203/88A 1987-10-30 1988-10-27 Imidazo(1,2-a)(pyridazines or pyrazines) for treatment of diseases related to bone loss Abandoned AU2620388A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8704248 1987-10-30
SE8704248A SE8704248D0 (en) 1987-10-30 1987-10-30 MEDICAL USE

Publications (1)

Publication Number Publication Date
AU2620388A true AU2620388A (en) 1989-05-23

Family

ID=20370069

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26203/88A Abandoned AU2620388A (en) 1987-10-30 1988-10-27 Imidazo(1,2-a)(pyridazines or pyrazines) for treatment of diseases related to bone loss

Country Status (9)

Country Link
EP (1) EP0339071A1 (en)
JP (1) JPH02501929A (en)
KR (1) KR890701587A (en)
AU (1) AU2620388A (en)
DK (1) DK322189D0 (en)
HU (1) HU203663B (en)
IL (1) IL88205A0 (en)
SE (1) SE8704248D0 (en)
WO (1) WO1989003833A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615666B2 (en) * 1987-07-16 1991-10-10 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazols

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081253A (en) * 1989-12-21 1992-01-14 American Home Products Corporation Imidazo(4,5-c)pyridines as antiosteoporotic agents
US5464843A (en) * 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
WO1996034866A1 (en) * 1995-05-01 1996-11-07 Fujisawa Pharmaceutical Co., Ltd. Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivatives and their use as bone resorption inhibitors
GB9518552D0 (en) * 1995-09-11 1995-11-08 Fujisawa Pharmaceutical Co New heterocyclic compounds
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
JP5918264B2 (en) 2010-12-22 2016-05-18 アッヴィ・インコーポレイテッド Hepatitis C inhibitor and use thereof
DE102012200349A1 (en) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituted fused pyrimidines and triazines and their use
US9624214B2 (en) 2012-11-05 2017-04-18 Bayer Pharma Aktiengesellschaft Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US8778964B2 (en) 2012-11-05 2014-07-15 Bayer Pharma Aktiengesellschaft Hydroxy-substituted imidazo[1,2-a]-pyridinecarboxamides and their use
US8796305B2 (en) 2012-11-05 2014-08-05 Bayer Pharma Aktiengesellschaft Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US9126998B2 (en) 2012-11-05 2015-09-08 Bayer Pharma AG Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
ES2625744T3 (en) 2013-06-04 2017-07-20 Bayer Pharma Aktiengesellschaft Imidazo [1,2-a] pyridines substituted with 3-aryl and their use
MX2016000258A (en) 2013-07-10 2016-04-28 Bayer Pharma AG Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof.
JP2017507140A (en) 2014-02-19 2017-03-16 バイエル・ファルマ・アクティエンゲゼルシャフト 3- (Pyrimidin-2-yl) imidazo [1,2-a] pyridine
EP3119777A1 (en) 2014-03-21 2017-01-25 Bayer Pharma Aktiengesellschaft Cyano-substituted imidazo[1,2-a]pyridinecarboxamides and their use
CN106459047A (en) * 2014-05-02 2017-02-22 拜耳医药股份有限公司 Imidazo[1,2‑a]pyridines as stimulators of soluble guanylate cyclase for the treatment of cardiovascular disease
CA2947372A1 (en) * 2014-05-02 2015-11-05 Bayer Pharma Aktiengesellschaft 6-chlorine-substituted imidazo[1,2-a]pyridine carboxamides and the use thereof as soluble guanylate cyclase stimulators
US20170057958A1 (en) 2014-05-02 2017-03-02 Bayer Pharma Aktiengesellschaft Enantiomers of the n-(2-amino-5-fluoro-2-methylpentyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide, as well as of the di- and trifluoro derivatives for the treatment of cardiovascular diseases
CN107001361A (en) 2014-12-02 2017-08-01 拜耳医药股份有限公司 Imidazo [1,2 a] pyridine of heteroaryl substitution and application thereof
US10174021B2 (en) 2014-12-02 2019-01-08 Bayer Pharma Aktiengesellschaft Substituted pyrazolo[1,5-A]pyridines and their use
EP3286185A1 (en) 2015-02-05 2018-02-28 Bayer Pharma Aktiengesellschaft Substituted pyrazolo[1,5-a]-pyridine-3-carboxamides and use thereof
US10150773B2 (en) 2015-02-05 2018-12-11 Bayer Pharma Aktiengesellschaft N-substituted 8-[(2,6-difluorobenzyl)oxy]-2,6- dimethylimidazo[1,2-a]pyrazin-3-carboxamide derivatives as stimulators of soluble guanylate cyclase (SGC) for the treatment of cardiovascular diseases
WO2018184976A1 (en) 2017-04-05 2018-10-11 Bayer Pharma Aktiengesellschaft Substituted imidazo[1,2-a]pyridinecarboxamides and use of same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
DE3446778A1 (en) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach NEW IMIDAZO DERIVATIVES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615666B2 (en) * 1987-07-16 1991-10-10 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazols

Also Published As

Publication number Publication date
SE8704248D0 (en) 1987-10-30
WO1989003833A1 (en) 1989-05-05
EP0339071A1 (en) 1989-11-02
DK322189A (en) 1989-06-28
JPH02501929A (en) 1990-06-28
HUT51138A (en) 1990-04-28
IL88205A0 (en) 1989-06-30
DK322189D0 (en) 1989-06-28
HU203663B (en) 1991-09-30
KR890701587A (en) 1989-12-21

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