AU2591800A - Synthetic and therapeutic methods for the alpha and beta domains of metallothionein - Google Patents

Synthetic and therapeutic methods for the alpha and beta domains of metallothionein

Info

Publication number: AU2591800A
Authority: AU; Australia
Prior art keywords: metallothionein; alpha; synthetic; therapeutic methods; beta domains
Prior art date: 1998-12-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU25918/00A

Inventor

Bert L. Vallee

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-23

Filing date

1999-12-21

Publication date

2000-07-31

1999-12-21 Application filed by Individual filed Critical Individual

2000-07-31 Publication of AU2591800A publication Critical patent/AU2591800A/en

Status Abandoned legal-status Critical Current

Links

DIGQNXIGRZPYDK-WKSCXVIASA-N (2R)-6-amino-2-[[2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2R,3S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S,3S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[2-[(2-amino-1-hydroxyethylidene)amino]-3-carboxy-1-hydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]hexanoic acid Chemical compound C[C@@H]([C@@H](C(=N[C@@H](CS)C(=N[C@@H](C)C(=N[C@@H](CO)C(=NCC(=N[C@@H](CCC(=N)O)C(=NC(CS)C(=N[C@H]([C@H](C)O)C(=N[C@H](CS)C(=N[C@H](CO)C(=NCC(=N[C@H](CS)C(=NCC(=N[C@H](CCCCN)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](CS)N=C([C@H](CO)N=C([C@H](CO)N=C([C@H](C)N=C(CN=C([C@H](CO)N=C([C@H](CS)N=C(CN=C(C(CS)N=C(C(CC(=O)O)N=C(CN)O)O)O)O)O)O)O)O)O)O)O)O DIGQNXIGRZPYDK-WKSCXVIASA-N 0.000 title 1
102000003792 Metallothionein Human genes 0.000 title 1
108090000157 Metallothionein Proteins 0.000 title 1
238000010189 synthetic method Methods 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/825—Metallothioneins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU25918/00A 1998-12-23 1999-12-21 Synthetic and therapeutic methods for the alpha and beta domains of metallothionein Abandoned AU2591800A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11345998P	1998-12-23	1998-12-23
US60113459		1998-12-23
PCT/US1999/030573 WO2000038654A1 (en)	1998-12-23	1999-12-21	Synthetic and therapeutic methods for the alpha and beta domains of metallothionein

Publications (1)

Publication Number	Publication Date
AU2591800A true AU2591800A (en)	2000-07-31

Family

ID=22349564

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU25918/00A Abandoned AU2591800A (en)	1998-12-23	1999-12-21	Synthetic and therapeutic methods for the alpha and beta domains of metallothionein

Country Status (2)

Country	Link
AU (1)	AU2591800A (en)
WO (1)	WO2000038654A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2196978B1 (en) *	2001-10-26	2005-03-16	Universitat Autonoma De Barcelona	PHARMACEUTICAL COMPOSITION
US7655620B2 (en) *	2005-07-07	2010-02-02	Cancure Laboratories, Llc	Use of one or more metal carriers to selectively kill mammalian cells
US8618060B2 (en)	2006-02-14	2013-12-31	University Of Tasmania	Metallothionein-derived peptide fragments
CN102462687B (en) *	2010-11-12	2013-08-14	上海医药工业研究院	Pharmaceutical composition containing GC-20

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR207116A1 (en) *	1973-03-28	1976-09-15	Ciba Geigy Ag	PROCEDURE TO PREPARE NEW DOTRIACONTAPEPTIDOAMIDES
US4732864A (en) *	1983-10-06	1988-03-22	E. I. Du Pont De Nemours And Company	Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
EP0700304A4 (en) *	1993-05-17	1999-01-07	Immunomedics Inc	Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates

1999
- 1999-12-21 WO PCT/US1999/030573 patent/WO2000038654A1/en not_active Ceased
- 1999-12-21 AU AU25918/00A patent/AU2591800A/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2000038654A1 (en)	2000-07-06
WO2000038654B1 (en)	2000-08-17

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Legal Events

Date	Code	Title	Description
2001-09-20	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase