AU2386184A - Preparation of acylglycoprotein - Google Patents
Preparation of acylglycoproteinInfo
- Publication number
- AU2386184A AU2386184A AU23861/84A AU2386184A AU2386184A AU 2386184 A AU2386184 A AU 2386184A AU 23861/84 A AU23861/84 A AU 23861/84A AU 2386184 A AU2386184 A AU 2386184A AU 2386184 A AU2386184 A AU 2386184A
- Authority
- AU
- Australia
- Prior art keywords
- alkanol
- supernatant
- precipitate
- isolated
- molecular weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 102000003886 Glycoproteins Human genes 0.000 abstract 4
- 108090000288 Glycoproteins Proteins 0.000 abstract 4
- 239000002244 precipitate Substances 0.000 abstract 4
- 239000006228 supernatant Substances 0.000 abstract 4
- 241000588747 Klebsiella pneumoniae Species 0.000 abstract 2
- 239000012141 concentrate Substances 0.000 abstract 2
- 150000004820 halides Chemical class 0.000 abstract 2
- 239000006166 lysate Substances 0.000 abstract 2
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 2
- 238000011026 diafiltration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/26—Klebsiella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
For the Contracting States BE CH DE GB IT LI LU NL SE 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by diafiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtined, the supernatant is concentrated by use of at least one means of selection of molecules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried. For the Contracting State AT 1. Preparation process for glycoproteins in which, in order, a solution of purified glycoproteins is prepared by dialfiltration of an extract of a lysate of cultures of Klebsiella pneumoniae, the said solution is treated with a halide of a quaternary ammonium, the supernatant is isolated by eliminating the precipitate so obtained, the supernatant is concentrated by use of at least one means of selection of molelules, the concentrate is treated cold with at least one alkanol of low molecular weight, the precipitate so obtained is isolated and, if desired, is washed with at least one alkanol of low molecular weight and dried.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301345 | 1983-01-28 | ||
| FR8301345A FR2540136A1 (en) | 1983-01-28 | 1983-01-28 | NOVEL PROCESS FOR THE PREPARATION OF IMMUNOSTIMULATING ACYLGLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR CONTROLLING ALLERGIC DISEASES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2386184A true AU2386184A (en) | 1984-08-02 |
| AU559247B2 AU559247B2 (en) | 1987-03-05 |
Family
ID=9285393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU23861/84A Ceased AU559247B2 (en) | 1983-01-28 | 1984-01-27 | Preparation of acylglycoprotein |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0115988B1 (en) |
| JP (1) | JPS59141594A (en) |
| KR (1) | KR910009162B1 (en) |
| AT (1) | ATE22925T1 (en) |
| AU (1) | AU559247B2 (en) |
| CA (1) | CA1244405A (en) |
| DE (1) | DE3460982D1 (en) |
| DK (1) | DK37384A (en) |
| ES (1) | ES8500326A1 (en) |
| FI (1) | FI78304C (en) |
| FR (1) | FR2540136A1 (en) |
| HU (1) | HU195538B (en) |
| IE (1) | IE56612B1 (en) |
| IL (1) | IL70731A (en) |
| NZ (1) | NZ206959A (en) |
| PT (1) | PT78012B (en) |
| ZA (1) | ZA84537B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2574429B1 (en) * | 1984-12-06 | 1987-12-11 | Roussel Uclaf | ACYLGLYCANNES EXTRACTED FROM KLEBSIELLA, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE COMPOSITIONS CONTAINING THEM |
| FR2598434B1 (en) * | 1986-05-12 | 1988-09-16 | Pf Medicament | NEW IMMUNOMODULATORS OBTAINED BY HEMISYNTHESIS FROM A BACTERIAL POLYSACCHARIDE ISOLATED FROM AN UNCAPSULATED MUTANT STRAIN OF KLEBSIELLA PNEUMONIAE |
| FR2650506B1 (en) * | 1989-07-11 | 1991-11-08 | Roussel Uclaf | GALACTANNE EXTRACT OF KLEBSIELLA, PROCESS FOR OBTAINING AND APPLICATION AS A MEDICAMENT |
| JP3662550B2 (en) * | 2002-05-08 | 2005-06-22 | 高砂香料工業株式会社 | Powder composition |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2396019A1 (en) * | 1977-07-01 | 1979-01-26 | Cassenne Lab Sa | Acetylated water soluble gluco-peptide prepn. - from pseudomonas aeruginosa; used as antiinflammatories, antibacterials, and immunostimulant(s) |
| FR2396020A1 (en) * | 1977-07-01 | 1979-01-26 | Cassenne Lab Sa | NEW WATER-SOLUBLE GLYCOPEPTIDES ACETYL EXTRACTS FROM MICROBIAL BODIES LYES OF HAFNIA, AEROBACTER CLOACAE AND KLEBSIELLA PNEUMONIAE, METHOD OF PREPARATION AND APPLICATION OF THESE PRODUCTS AS MEDICINAL PRODUCTS |
| FR2444464A1 (en) * | 1978-12-19 | 1980-07-18 | Fabre Sa Pierre | PURIFIED BACTERIAL PROTEOGLYCANS, PROCESS FOR THEIR PREPARATION AND VACCINE CONTAINING THEM |
| FR2462477A1 (en) * | 1979-07-31 | 1981-02-13 | Cassenne Lab Sa | NOVEL KLEBSIELLA PNEUMONIAE GLYCOPROTEINS, PROCESS FOR OBTAINING THEM, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM |
| FR2490496A1 (en) * | 1980-09-19 | 1982-03-26 | Roussel Uclaf | NEW IMMUNOSTIMULANT GLYCOPROTEINS EXTRACTED FROM KLEBSIELLA PNEUMONIAE, PROCESS FOR OBTAINING THEM, THEIR APPLICATION AS MEDICAMENTS AND COMPOSITIONS COMPRISING THE SAME |
| FR2523154A1 (en) * | 1982-03-09 | 1983-09-16 | Fabre Sa Pierre | PROCESS FOR THE PREPARATION OF INTERFERON-INDUCING IMMUNOSTIMULATING PROTEOGLYCANS, PROTEOGLYCANS OBTAINED AND MEDICAMENTS CONTAINING THEM |
-
1983
- 1983-01-28 FR FR8301345A patent/FR2540136A1/en active Granted
-
1984
- 1984-01-20 IL IL70731A patent/IL70731A/en unknown
- 1984-01-24 ZA ZA84537A patent/ZA84537B/en unknown
- 1984-01-26 EP EP84400172A patent/EP0115988B1/en not_active Expired
- 1984-01-26 AT AT84400172T patent/ATE22925T1/en not_active IP Right Cessation
- 1984-01-26 JP JP59011128A patent/JPS59141594A/en active Pending
- 1984-01-26 PT PT78012A patent/PT78012B/en not_active IP Right Cessation
- 1984-01-26 DE DE8484400172T patent/DE3460982D1/en not_active Expired
- 1984-01-27 CA CA000446183A patent/CA1244405A/en not_active Expired
- 1984-01-27 NZ NZ206959A patent/NZ206959A/en unknown
- 1984-01-27 IE IE186/84A patent/IE56612B1/en not_active IP Right Cessation
- 1984-01-27 HU HU84380A patent/HU195538B/en not_active IP Right Cessation
- 1984-01-27 FI FI840351A patent/FI78304C/en not_active IP Right Cessation
- 1984-01-27 DK DK37384A patent/DK37384A/en not_active Application Discontinuation
- 1984-01-27 AU AU23861/84A patent/AU559247B2/en not_active Ceased
- 1984-01-27 KR KR1019840000357A patent/KR910009162B1/en not_active Expired
- 1984-01-27 ES ES529224A patent/ES8500326A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NZ206959A (en) | 1987-03-31 |
| ES529224A0 (en) | 1984-10-01 |
| FI840351A0 (en) | 1984-01-27 |
| FR2540136B1 (en) | 1985-05-03 |
| IE56612B1 (en) | 1991-10-09 |
| ES8500326A1 (en) | 1984-10-01 |
| IL70731A (en) | 1987-10-20 |
| KR910009162B1 (en) | 1991-10-31 |
| CA1244405A (en) | 1988-11-08 |
| ATE22925T1 (en) | 1986-11-15 |
| ZA84537B (en) | 1985-02-27 |
| IL70731A0 (en) | 1984-04-30 |
| PT78012B (en) | 1986-06-18 |
| KR840007439A (en) | 1984-12-07 |
| EP0115988A1 (en) | 1984-08-15 |
| IE840186L (en) | 1984-07-28 |
| AU559247B2 (en) | 1987-03-05 |
| FI840351L (en) | 1984-07-29 |
| EP0115988B1 (en) | 1986-10-15 |
| FR2540136A1 (en) | 1984-08-03 |
| FI78304C (en) | 1989-07-10 |
| DE3460982D1 (en) | 1986-11-20 |
| HU195538B (en) | 1988-05-30 |
| DK37384D0 (en) | 1984-01-27 |
| JPS59141594A (en) | 1984-08-14 |
| FI78304B (en) | 1989-03-31 |
| DK37384A (en) | 1984-07-29 |
| PT78012A (en) | 1984-02-01 |
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