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AU2223495A - Spiro compound and medicinal composition thereof - Google Patents

Spiro compound and medicinal composition thereof

Info

Publication number
AU2223495A
AU2223495A AU22234/95A AU2223495A AU2223495A AU 2223495 A AU2223495 A AU 2223495A AU 22234/95 A AU22234/95 A AU 22234/95A AU 2223495 A AU2223495 A AU 2223495A AU 2223495 A AU2223495 A AU 2223495A
Authority
AU
Australia
Prior art keywords
medicinal composition
spiro compound
spiro
compound
medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22234/95A
Inventor
Masahiro Fujii
Ken Ikeda
Yasuo Isomura
Akio Kakefuda
Hirokazu Kubota
Hitoshi Nagaoka
Yoshinori Okamoto
Osamu Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of AU2223495A publication Critical patent/AU2223495A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22234/95A 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof Abandoned AU2223495A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP10193694 1994-04-15
JP6-101936 1994-04-15
JP25538294 1994-10-20
JP6-255382 1994-10-20
PCT/JP1995/000713 WO1995028389A1 (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Publications (1)

Publication Number Publication Date
AU2223495A true AU2223495A (en) 1995-11-10

Family

ID=26442705

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22234/95A Abandoned AU2223495A (en) 1994-04-15 1995-04-12 Spiro compound and medicinal composition thereof

Country Status (2)

Country Link
AU (1) AU2223495A (en)
WO (1) WO1995028389A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU224225B1 (en) 1995-12-01 2005-06-28 Sankyo Co. Ltd. Heterocyclic compounds having tachykinin receptor antagonist activity, their preparation, and their use for the preparation of pharmaceutical compositions
JP3017147B2 (en) 1996-11-08 2000-03-06 三共株式会社 Optically active sulfoxide derivative
JP3192631B2 (en) 1997-05-28 2001-07-30 三共株式会社 Pharmaceuticals consisting of saturated heterocyclic compounds
DK0987269T3 (en) 1997-05-30 2003-10-06 Sankyo Co Salts of optically active sulfoxide derivative
WO1999021823A1 (en) * 1997-10-27 1999-05-06 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US6265614B1 (en) 1997-10-27 2001-07-24 Schering Corporation Optically active intermediates for the preparation of optically active substituted oximes, hydrazones and olefins useful as neurokinin antagonists
WO1999028307A1 (en) * 1997-12-04 1999-06-10 Sankyo Company, Limited Alicyclic acylated heterocyclic derivatives
BR0116113A (en) 2000-12-12 2004-08-03 Neurogen Corp Spiro [isobenzofuran-1,4'-piperidin] -3-ones and 3h-spiroisoben-zofuran-1,4'-piperidines
EP1695977A3 (en) * 2000-12-12 2006-09-20 Neurogen Corporation Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines
US20040106635A1 (en) * 2001-03-29 2004-06-03 Iwao Takamuro Spiroisoquinoline compound, a method for preparing the same and an intermediate thereof
US20030078278A1 (en) * 2001-06-26 2003-04-24 Pfizer Inc. Spiropiperidine compounds as ligands for ORL-1 receptor
US7396930B2 (en) 2002-06-11 2008-07-08 Sankyo Company, Limited Process for producing cyclic thioether and synthetic intermediate thereof
ATE402176T1 (en) * 2002-12-13 2008-08-15 Smithkline Beecham Corp PYRROLIDINE AND AZETIDINE COMPOUNDS ALSCCR5 ANTAGONISTS
US7786141B2 (en) 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
JP2008510728A (en) 2004-08-19 2008-04-10 バーテックス ファーマシューティカルズ インコーポレイテッド Muscarinic receptor modulators
JP2008521825A (en) 2004-11-29 2008-06-26 バーテックス ファーマシューティカルズ インコーポレイテッド Muscarinic receptor modulators
JP4769464B2 (en) * 2005-01-12 2011-09-07 広栄化学工業株式会社 Method for producing alcohol compound
WO2007055418A1 (en) 2005-11-10 2007-05-18 Banyu Pharmaceutical Co., Ltd. Aza-substituted spiro derivative
CN101374519A (en) 2005-12-22 2009-02-25 弗特克斯药品有限公司 Modulators of muscarinic receptors
JP2009527568A (en) 2006-02-22 2009-07-30 バーテックス ファーマシューティカルズ インコーポレイテッド Modulator of muscarinic receptor
NZ570497A (en) 2006-02-22 2011-09-30 Vertex Pharma Spiro condensed 4,4'-quinilino-piperidines derivatives as modulators of muscarinic receptors
EP2040706A2 (en) 2006-06-29 2009-04-01 Vertex Pharmceuticals Incorporated Modulators of muscarinic receptors
CN101553231A (en) 2006-08-15 2009-10-07 弗特克斯药品有限公司 Modulators of muscarinic receptors
JP2010501561A (en) 2006-08-18 2010-01-21 バーテックス ファーマシューティカルズ インコーポレイテッド Modulator of muscarinic receptor
JP2010516731A (en) 2007-01-24 2010-05-20 グラクソ グループ リミテッド Pharmaceutical composition comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-1-yl) -benzyl]-(2S-phenyl-piperidin-3S-yl) -amine
MX2010003373A (en) 2007-10-03 2010-04-30 Vertex Pharma Modulators of muscarinic receptors.
CN102762556B (en) 2009-11-05 2017-04-26 圣母大学 Imidazo[1,2-a]pyridine compounds and methods for their synthesis and use
CA2967097A1 (en) * 2014-11-21 2016-05-26 Laboratorios Del Dr. Esteve, S.A. Spiro-isoquinoline-1,4'-piperidine compounds having multimodal activity against pain
IL257743B (en) 2015-09-17 2022-08-01 Marvin J Miller Heterocyclic compounds containing benzyl amine and preparations useful against mycobacterial inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962259A (en) * 1973-12-12 1976-06-08 American Hoechst Corporation 1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof
ES468860A1 (en) * 1977-04-21 1979-09-16 Hoechst Ag Spiro(indoline-3,4'-piperidine)s and related compounds
JPS55143980A (en) * 1979-04-27 1980-11-10 Dai Ichi Seiyaku Co Ltd Anti-allergic preparation
GB8917069D0 (en) * 1989-07-26 1989-09-13 Merck Sharp & Dohme Therapeutic agents
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1995028389A1 (en) 1995-10-26

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