AU2128900A - Procedure and device for the application of cosmetic products at controlled temperatures - Google Patents
Procedure and device for the application of cosmetic products at controlled temperatures Download PDFInfo
- Publication number
- AU2128900A AU2128900A AU21289/00A AU2128900A AU2128900A AU 2128900 A AU2128900 A AU 2128900A AU 21289/00 A AU21289/00 A AU 21289/00A AU 2128900 A AU2128900 A AU 2128900A AU 2128900 A AU2128900 A AU 2128900A
- Authority
- AU
- Australia
- Prior art keywords
- cosmetic preparation
- ampoule
- dispenser
- components
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000002537 cosmetic Substances 0.000 title claims description 32
- 238000000034 method Methods 0.000 title claims description 17
- 238000002360 preparation method Methods 0.000 claims description 33
- 239000003708 ampul Substances 0.000 claims description 12
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 9
- 208000035484 Cellulite Diseases 0.000 claims description 5
- 206010049752 Peau d'orange Diseases 0.000 claims description 5
- 239000000499 gel Substances 0.000 claims description 5
- 206010047791 Vulvovaginal dryness Diseases 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 230000001815 facial effect Effects 0.000 claims description 2
- 239000006210 lotion Substances 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 4
- 239000001110 calcium chloride Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 206010020565 Hyperaemia Diseases 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 206010047141 Vasodilatation Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 230000036232 cellulite Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000024883 vasodilation Effects 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- -1 anhydride compounds Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000010972 statistical evaluation Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 230000003639 vasoconstrictive effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3261—Flexible containers having several compartments
- B65D81/3266—Flexible containers having several compartments separated by a common rupturable seal, a clip or other removable fastening device
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D40/00—Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/34—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging foodstuffs or other articles intended to be cooked or heated within the package
- B65D81/3484—Packages having self-contained heating means, e.g. heating generated by the reaction of two chemicals
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Food Science & Technology (AREA)
- Cosmetics (AREA)
- Package Specialized In Special Use (AREA)
Description
WO 00/43286 1 PCT/IT00/00013 Description "PROCEDURE AND DEVICE FOR THE APPLICATION OF COSMETIC PRODUCTS AT CONTROLLED TEMPERATURES" Technical field 5 The present invention relates to a procedure for bringing a cosmetic product to a controlled temperature for a predetermined period for the purpose of improving its application. The invention also relates to devices to achieve the aforementioned procedure. Background art 10 It is known that temperature variations have a significant influence on the level of activity of a cosmetic preparation. It is also known that the structure of the skin and its ability to modify its reactions because of a buffer effect have always been influenced by the gradient between ambient temperature and body temperature. The skin reacts to contact with hotter substances by pronounced vasodilatation and in general with 15 appreciable hyperemia. The application of a hot product provokes hyperemia and consequent dilatation of the skin surface, thus facilitating the entry and absorption of the cosmetic substance contained in the product. The hot application of cosmetic product requires the availability of a source of heat to warm up the cosmetic preparation and accurate control of the treatment temperature. 20 Application at too high a temperature or for much longer than prescribed may cause damage to the treated part. On the other hand, the use of too low a temperature may not give the expected results. The problem of the temperature of application does not arise when treatment takes place in specialized centers, but it considerably limits the achievement of good results when 25 treatment is carried out personally or in small ill-equipped centers. It would be highly advantageous to have a procedure for the application of cosmetic products at a controlled temperature which could be maintained for a predetermined period and which does not require apparatus for heating or temperature control. Disclosure of invention 30 The first objective of the present invention is the creation of a simple and low-cost procedure for heating cosmetic products at the moment of application to a predetermined temperature without using heat sources external to the product package.
WO 00/43286 PCT/IT00/00013 2 The second objective of the present invention is a device which contains the dose of cosmetic preparation and allows the said dose to be raised to the required temperature in a simple operation. The procedure according to the present invention consists of holding the cosmetic 5 preparation in a container whose outer walls are in contact with, or form an integral part of, a second container in which there are two or more separated compounds which, when mixed in suitable proportions, develop the heat necessary to raise the temperature of the cosmetic preparation to that required. The components which generate heat when mixed are in individual compartments separated by walls made from an easily ruptured 10 material. The components which constitute the self-heating mixture are well known and comprise salts or anhydride compounds which develop heat when mixed with water, which is usually the second component. The preferred components are anhydrous calcium chloride and water. 15 The cosmetic preparations which can be used according to the procedure of the present invention are all those whose action is favored by their deep absorption due to vasodilatation. Thus anti-cellulite preparations, gels to prevent vaginal' dryness, cleansing facial masks, hair lotions, and anti-wrinkling oils are advantageously used. It is also possible to use products of thermal-bath type or origin, such as mud-packs or 20 water, which recreate thermal-bath ambiance and conditions when applied hot. The temperatures to which the cosmetic preparations must be raised according to the present invention, vary between 37 0 C and 65 0 C depending on the cosmetic preparation involved, the sensitivity of the person undergoing the treatment, and the type of treatment. It is possible to produce packs of the same product which can be heated to 25 different temperatures by varying the relative proportions and the quantities of'the components of the heating mixture. It is also possible to specify application at different times after the initiation of the heating process, thus enabling different temperatures of application to be used. Another objective of the present invention is to provide a device which can be 30 advantageously used in the above applications. The device according to the present invention consists of a receptacle or ampoule containing the cosmetic preparation to which is attached a long tubular element closed at its extremity which constitutes the dispenser. The ampoule is completely enclosed in -WO 00/43286 PCT/ITOQ/00013 3 a container from which protrudes the closed extremity of the dispenser. The container comprises a plurality of separate compartments or bags which contain water or the heating agent, generally anhydrous calcium chloride. The rupture of the bags causes the components to mix and heat the ampoule containing the cosmetic 5 preparation. It is sufficient to cut the extremity of the dispenser to deliver the cosmetic preparation at the desired temperature. The relative quantities of water and calcium chloride can be measured to give a range of treatment temperatures. By dosing the quantities of calcium chloride in the plurality of bags, a range of heating levels of the preparation can be obtained with a single package. 10 Brief description of the drawing The advantages of the procedure according to the invention and the method of implementing it will be better understood from the examples of application which follow and which are by way of example only and should not be considered limiting in any way. 15 To describe in detail the preferred method of implementing the procedure according to the invention, the single attached drawing shows a prospective view, partly in section, of a device for the application of a heated cosmetic preparation. Figure 1 indicates the ampoule 1 containing the cosmetic preparation 2 equipped with a tubular dispenser 3 which presents a peripheral canula 4 at its extremity to permit the 20 removal of the terminal part at the moment of application of the cosmetic preparation. The ampoule 1, made of deformable material, is inserted into a container 5 which contains granules of anhydrous calcium chloride 6. Inside the container 5 are two bags 7 and 8 which contain water and which are separated from the area in which the granules of calcium chloride 6 are contained by the impermeable walls of the bags. The 25 impermeable walls of the bags may be ruptured (from the outside) by applying manual pressure to weakened zones 9. The rupture of the bag or bags (7, 8) causes contact between the calcium chloride 6 and the water, with the heat of hydration being giyen off. After shaking the container 5 for a specified time, the preparation 2 inside the ampoule 1 reaches the predetermined temperature and is ready for application. For this 30 purpose, the extremity of the tubular dispenser 3 is removed by cutting the tubular element in the region of the peripheral canula 4, permitting the cosmetic preparation to be squeezed out by slight pressure applied to the ampoule 1.
-WO 00/43286 PCT/IT00/00013 4 Applications of cosmetic preparations have been carried out using the device as described above and the results compared with similar applications carried out at ambient temperature: Trial No.1 5 TREATMENT OF CELLULITE An anti-cellulite oil-type product was applied with ten-minute massage to both legs of ten patients for 16 days at ambient temperature. A statistical evaluation was conducted of the regression of the cellulite situation to compare it with the results obtained by the application of the same preparation at 50 0 C. 10 The results showed acceleration of regression, which could be defined as: 1. achieving the same results in reduced periods of time, from 20% to 30% less depending on the cases, (i.e. the same level of results after only 10/12 days of application). 2. at least 10% of an increase in the final result for the same period of standard 15 treatment of 15 days. Angiographic measurement by ultrasound scan showed : 1. significant increase in hyperemia from the stimulus and activation of the superficial and intra-dermal circulation. 20 2. increase in circulatory activity and in lymphatic duct activity at the deep dermal level because of the impact of the active agents of the preparation reaching, such levels. 25 Trial No . 2 TREATMENT OF VAGINAL DRYNESS Gel application at ambient temperature and at 38 0 C. to prevent vaginal dryness was studied in five cases. The problem of application of preparations to mucosal areas which are particularly 30 sensitive to temperature variations occurs again in the case of vaginal dryness. There was an unexpected vasoconstictive reaction to contact with the mucosa by the gel at a lower temperature than the area treated, with consequent difficult and limited absorption, and reduced benefit.
-WO 00/43286 PCT/IT00/00013 5 The ability to apply the gel at temperatures much closer to body temperature has meant the elimination of the vasoconstrictive phenomenon, showing objective improvement in the situation in shorter time and for longer periods.
Claims (8)
1. Procedure for heating a cosmetic preparation to a predetermined temperature at the moment of application, without the use of sources of heat external to the preparation 5 package, characterized by the cosmetic preparation being inserted into a contaiiner whose external walls are in contact with, or constitute an integral part of, a second. container in which are separately contained two or more components which; being mixed in suitable proportions, develop the heat to warm the cosmetic preparation to the desired temperature, the said components being kept separated in compartments 10 delimited by walls which are easily ruptured to allow their mixture.
2. Procedure according to Claim 1, characterized by the cosmetic preparation being selected from among anti-cellulite preparations, gels against vaginal dryness, cleansing facial masks, hair lotions, anti-wrinkling oil, products of thermal-spring origin and thermal-spring type synthesis products. 15
3. Procedure according to Claim 1 and/or 2, characterized by the components which are mixed to develop the heat necessary to raise the temperature of the cosmetic preparation being anhydrous calcium chloride and water.
4. Procedure according to one or more of Claims 1 to 3, characterized by the quantities of components selected and their relative proportions being chosen on the basis of 20 the treatment temperature desired.
5. Device for the realization of the procedure according to one or more of Claims 1 to 4, characterized by comprising a receptacle or ampoule 1 containing the cosmetic preparation 2 to which is fixed an elongated tubular element 3, closed at its extremity which forms the dispenser, the ampoule 1 being completely enclosed in a 25 container 5 from which the closed extremity of dispenser 3 protrudes, the container 5 containing anhydrous calcium chloride and providing separate bags, 7 and 8, which contain water, the rupture of the said bags causing the mixing of the components and the heating of the ampoule containing the cosmetic preparation, the extremity of the dispenser being removed to allow the cosmetic preparation to be 30 dispensed at the desired temperature.
6. Device according to Claim 5, characterized by the anhydrous calcium chloride being in the container 5 and the water being present in the bags 7 and 8. WO 00/43286 PCT/IT00/00013 7
7. Device according to Claim 5 or 6, characterized by the dispenser 3 having at its extremity a peripheral canula 4 to facilitate the removal of the terminal part.
8. Device according to Claim 5 and/or 6, characterized by the ampoule 1 being made of a compressible material to facilitate the delivery of the cosmetic preparation 5 through the dispenser tube 3 by means of light pressure on the walls of the said ampoule 1.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000084A ITMI990084A1 (en) | 1999-01-19 | 1999-01-19 | PROCEDURE AND DEVICE FOR THE APPLICATION OF COSMETIC PRODUCTS CONTROLLED TEMPERATURE |
| ITMI99A000084 | 1999-01-19 | ||
| PCT/IT2000/000013 WO2000043286A1 (en) | 1999-01-19 | 2000-01-13 | Procedure and device for the application of cosmetic products at controlled temperatures |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2128900A true AU2128900A (en) | 2000-08-07 |
Family
ID=11381528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU21289/00A Abandoned AU2128900A (en) | 1999-01-19 | 2000-01-13 | Procedure and device for the application of cosmetic products at controlled temperatures |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1147056A1 (en) |
| JP (1) | JP2002535295A (en) |
| AU (1) | AU2128900A (en) |
| BR (1) | BR0008893A (en) |
| CA (1) | CA2359671A1 (en) |
| HU (1) | HUP0105100A3 (en) |
| IT (1) | ITMI990084A1 (en) |
| MX (1) | MXPA01007275A (en) |
| WO (1) | WO2000043286A1 (en) |
| YU (1) | YU52001A (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1312097B1 (en) | 1999-04-23 | 2002-04-04 | Istituto Profilattico Italiano | PROCEDURE FOR THE APPLICATION OF COSMETIC PRODUCTS AT A CONTROLLED TEMPERATURE LOWER THAN THE AMBIENT TEMPERATURE. |
| AU8006200A (en) * | 1999-10-08 | 2001-04-23 | Procter & Gamble Company, The | Applicator having a temperature changing element for distributing a product ontoa target surface |
| DE10032799B4 (en) | 2000-06-28 | 2005-09-22 | Coty B.V. | Multi-chamber packaging for cooling or heating products |
| US6484514B1 (en) | 2000-10-10 | 2002-11-26 | The Procter & Gamble Company | Product dispenser having internal temperature changing element |
| US6547063B1 (en) | 2000-10-10 | 2003-04-15 | The Procter & Gamble Company | Article for the delivery of foam products |
| ITTO20020031U1 (en) * | 2002-02-08 | 2002-05-09 | Vanity Line S R L | SELF-HEATING CONTAINER FOR BODY CARE PRODUCTS, IN PARTICULAR SLUDGE, ALGAE AND HAIR REMOVAL PRODUCTS. |
| US6827080B2 (en) * | 2002-10-03 | 2004-12-07 | Kimberly-Clark Worldwide, Inc. | Pressure activated reaction vessel and package |
| FR2848397B1 (en) | 2002-12-13 | 2006-11-10 | Oreal | METHODS OF MAKE-UP AND APPLICATION OF A CARE PRODUCT AND DEVICES USED IN CARRYING OUT SUCH METHODS |
| WO2004054400A2 (en) | 2002-12-13 | 2004-07-01 | L'oreal | Make-up processes and processes for application of a skin care product, and devices used in the implementation of such processes |
| FR2848396B1 (en) | 2002-12-13 | 2005-07-08 | Oreal | METHODS OF MAKE-UP AND APPLICATION OF A CARE PRODUCT, AND DEVICES USED IN CARRYING OUT SUCH METHODS |
| FR2849753B1 (en) | 2003-01-13 | 2006-08-18 | Oreal | METHOD FOR HEATING A SUPPORT ON WHICH OR INSIDE A COSMETIC PRODUCT |
| ES2246137B1 (en) * | 2004-04-21 | 2007-04-01 | Pedro Luis Labella Arnanz | ROLL-ON DEPILATORY AND SELF-HEATING WAX THROUGH A CHEMICAL REACTION. |
| FR2869818B1 (en) | 2004-05-06 | 2006-06-16 | Oreal | METHODS OF MAKE-UP AND APPLICATION OF A CARE PRODUCT, AND DEVICES USED IN CARRYING OUT SUCH METHODS |
| US7442439B2 (en) | 2005-12-28 | 2008-10-28 | Kimberly-Clark Worldwide, Inc. | Microencapsulated heat delivery vehicles |
| US7914891B2 (en) | 2005-12-28 | 2011-03-29 | Kimberly-Clark Worldwide, Inc. | Wipes including microencapsulated delivery vehicles and phase change materials |
| US7654412B2 (en) | 2006-05-30 | 2010-02-02 | Kimberly-Clark Worldwide, Inc. | Wet wipe dispensing system for dispensing warm wet wipes |
| US7497351B2 (en) | 2006-05-30 | 2009-03-03 | Kimberly-Clark Worldwide, Inc. | Wet wipe dispensing system |
| US8192841B2 (en) | 2006-12-14 | 2012-06-05 | Kimberly-Clark Worldwide, Inc. | Microencapsulated delivery vehicle having an aqueous core |
| US7517582B2 (en) | 2006-12-14 | 2009-04-14 | Kimberly-Clark Worldwide, Inc. | Supersaturated solutions using crystallization enthalpy to impart temperature change to wet wipes |
| US7924142B2 (en) | 2008-06-30 | 2011-04-12 | Kimberly-Clark Worldwide, Inc. | Patterned self-warming wipe substrates |
| FR2967756B1 (en) * | 2010-11-24 | 2012-12-28 | Oreal | DEVICE FOR HEATING A COSMETIC COMPOSITION |
| FR2967757B1 (en) * | 2010-11-24 | 2016-01-29 | Oreal | DEVICE FOR MICRO-ONDABLY HEATING A COSMETIC COMPOSITION |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2376401A1 (en) * | 1976-12-28 | 1978-07-28 | Joubert Georges | Cosmetic product dispensing apparatus - has casing in which bottles are mounted upside down over valves and heating unit for dispensation of heated cosmetics |
| GB2113096A (en) * | 1982-01-16 | 1983-08-03 | English Grains | Hot or cold pack |
| JPH0431271A (en) * | 1990-05-14 | 1992-02-03 | Powder Tec Kk | Exothermic package |
| US5263991A (en) * | 1992-10-21 | 1993-11-23 | Biomet, Inc. | Method for heating biocompatible implants in a thermal packaging line |
| US5628304A (en) * | 1995-06-22 | 1997-05-13 | G & S Regal Trading Corporation | Self-heating container |
-
1999
- 1999-01-19 IT IT1999MI000084A patent/ITMI990084A1/en unknown
-
2000
- 2000-01-13 CA CA002359671A patent/CA2359671A1/en not_active Abandoned
- 2000-01-13 YU YU52001A patent/YU52001A/en unknown
- 2000-01-13 EP EP00901328A patent/EP1147056A1/en not_active Withdrawn
- 2000-01-13 BR BR0008893-5A patent/BR0008893A/en not_active Application Discontinuation
- 2000-01-13 JP JP2000594713A patent/JP2002535295A/en not_active Withdrawn
- 2000-01-13 WO PCT/IT2000/000013 patent/WO2000043286A1/en not_active Ceased
- 2000-01-13 HU HU0105100A patent/HUP0105100A3/en unknown
- 2000-01-13 MX MXPA01007275A patent/MXPA01007275A/en unknown
- 2000-01-13 AU AU21289/00A patent/AU2128900A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002535295A (en) | 2002-10-22 |
| HUP0105100A3 (en) | 2002-12-28 |
| BR0008893A (en) | 2001-10-30 |
| YU52001A (en) | 2003-02-28 |
| WO2000043286A1 (en) | 2000-07-27 |
| ITMI990084A1 (en) | 2000-07-19 |
| MXPA01007275A (en) | 2002-06-04 |
| HUP0105100A2 (en) | 2002-04-29 |
| CA2359671A1 (en) | 2000-07-27 |
| EP1147056A1 (en) | 2001-10-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |