AU2039800A - 5-membered heterocycles for the treatment of human diseases involving modulatorsof selectins - Google Patents
5-membered heterocycles for the treatment of human diseases involving modulatorsof selectinsInfo
- Publication number
- AU2039800A AU2039800A AU20398/00A AU2039800A AU2039800A AU 2039800 A AU2039800 A AU 2039800A AU 20398/00 A AU20398/00 A AU 20398/00A AU 2039800 A AU2039800 A AU 2039800A AU 2039800 A AU2039800 A AU 2039800A
- Authority
- AU
- Australia
- Prior art keywords
- modulatorsof
- selectins
- treatment
- human diseases
- diseases involving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000003800 Selectins Human genes 0.000 title 1
- 108090000184 Selectins Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11102698P | 1998-12-04 | 1998-12-04 | |
| US11102598P | 1998-12-04 | 1998-12-04 | |
| US60111025 | 1998-12-04 | ||
| US60111026 | 1998-12-04 | ||
| PCT/US1999/028692 WO2000033836A1 (en) | 1998-12-04 | 1999-12-03 | 5-membered heterocycles for the treatment of human diseases involving modulators of selectins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2039800A true AU2039800A (en) | 2000-06-26 |
Family
ID=26808588
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU20398/00A Abandoned AU2039800A (en) | 1998-12-04 | 1999-12-03 | 5-membered heterocycles for the treatment of human diseases involving modulatorsof selectins |
| AU21643/00A Abandoned AU2164300A (en) | 1998-12-04 | 1999-12-03 | Substituted thiazoles for treatment of human diseases involving modulators of p-, l- and e- selectin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU21643/00A Abandoned AU2164300A (en) | 1998-12-04 | 1999-12-03 | Substituted thiazoles for treatment of human diseases involving modulators of p-, l- and e- selectin |
Country Status (2)
| Country | Link |
|---|---|
| AU (2) | AU2039800A (en) |
| WO (2) | WO2000034255A1 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2244474T3 (en) | 1999-09-29 | 2005-12-16 | Ortho-Mcneil Pharmaceutical, Inc. | ISONIPECOTAMIDE FOR THE TREATMENT OF DISORDERS MEDIATED BY INTEGRINE. |
| PL355912A1 (en) | 1999-11-22 | 2004-05-31 | Smithkline Beecham Plc. | Novel compounds |
| GB0028383D0 (en) | 2000-11-21 | 2001-01-03 | Novartis Ag | Organic compounds |
| GB0112348D0 (en) | 2001-05-19 | 2001-07-11 | Smithkline Beecham Plc | Compounds |
| WO2003007887A2 (en) | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
| WO2003059880A1 (en) | 2002-01-11 | 2003-07-24 | Sankyo Company, Limited | Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these |
| CN101870691A (en) | 2002-08-19 | 2010-10-27 | 劳洛斯治疗公司 | 2,4,5-Trisubstituted imidazoles and their use as antibacterial agents |
| ATE546456T1 (en) | 2003-05-30 | 2012-03-15 | Gemin X Pharmaceuticals Canada Inc | TRIHETEROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER |
| JP5095216B2 (en) | 2003-11-14 | 2012-12-12 | ローラス セラピューティクス インコーポレーテッド | Arylimidazoles and their use as anticancer agents |
| US20050148601A1 (en) * | 2003-12-19 | 2005-07-07 | Maynard George D. | Neurokinin-3 receptor modulators: diaryl imidazole derivatives |
| EP1711486B1 (en) | 2004-01-23 | 2011-05-11 | Nereus Pharmaceuticals, Inc. | Bis-indole pyrroles useful as antimicrobial agents |
| US7910617B2 (en) | 2004-02-24 | 2011-03-22 | Sankyo Company, Limited | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound |
| EP1577289A1 (en) | 2004-03-18 | 2005-09-21 | Revotar Biopharmaceuticals AG | Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders |
| ES2473597T3 (en) | 2005-05-25 | 2014-07-07 | Lorus Therapeutics Inc. | Derivatives of 2-indolyl imidazo [4,5-d] phenanthroline and its use in cancer treatment |
| EP1764093A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel aromatic compounds and their use in medical applications |
| EP1764095A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel nitrocatechol derivatives having selectin ligand activity |
| EP1764096A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel phloroglucinol derivatives having selectin ligand activity |
| JP2010501567A (en) | 2006-08-24 | 2010-01-21 | ノバルティス アクチエンゲゼルシャフト | 2- (pyrazin-2-yl) -thiazole and 2- (1H-pyrazole-3-) as stearoyl-CoA desaturase (SCD) inhibitors for the treatment of metabolic, cardiovascular and other disorders Yl) thiazole derivatives and related compounds |
| EP2066664A1 (en) | 2006-09-22 | 2009-06-10 | Novartis AG | Heterocyclic organic compounds |
| CN101595105B (en) | 2006-12-20 | 2013-01-23 | 诺瓦提斯公司 | 2-substituted 5-membered heterocycles as SCD inhibitors |
| CA2739488A1 (en) | 2008-10-15 | 2010-04-22 | Boehringer Ingelheim International Gmbh | Fused heteroaryl diamide compounds useful as mmp-13 inhibitors |
| US8785489B2 (en) | 2008-10-17 | 2014-07-22 | Boehringer Ingelheim International Gmbh | Heteroaryl substituted indole compounds useful as MMP-13 inhibitors |
| AU2010221650B2 (en) * | 2009-03-04 | 2015-06-25 | Merck Sharp & Dohme Corp. | Imidazole derivatives useful as modulators of FAAH and as FAAH imaging agents |
| WO2011005660A1 (en) | 2009-07-08 | 2011-01-13 | Valocor Therapeutics, Inc. | Tofa analogs useful in treating dermatological disorders or conditions |
| CN107007597A (en) | 2012-05-31 | 2017-08-04 | 菲尼克斯药品股份公司 | It is used as the thiazole of orphan nuclear receptor ROR γ instrumentalities through formamide or sulfonamide substitutions and the pharmaceutical applications of related derivatives |
| CA2903866A1 (en) | 2013-03-20 | 2014-09-25 | Aptose Biosciences Inc. | 2-substituted imidazo[4,5-d]phenanthroline derivatives and their use in the treatment of cancer |
| KR20160058960A (en) | 2013-10-04 | 2016-05-25 | 압토스 바이오사이언시스 인코포레이티드 | Compositions and methods for treating cancers |
| AU2018360477A1 (en) | 2017-10-30 | 2020-06-04 | Aptose Biosciences Inc. | Aryl imidazoles for the treatment of cancer |
| GB201905721D0 (en) | 2019-04-24 | 2019-06-05 | Univ Dundee | Compounds |
| CN114105881B (en) * | 2020-08-31 | 2024-01-26 | 沈阳海诺威医药科技有限公司 | Platelet aggregation inhibitor, and preparation method and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3002989A1 (en) * | 1980-01-29 | 1981-07-30 | Hoechst Ag, 6000 Frankfurt | HYDROXYPHENYL-THIAZOLE, -THIAZOLINE AND -THIAZOLIDINE-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR INFLUENCING COLLAGEN METABOLISM |
| US5753687A (en) * | 1995-06-19 | 1998-05-19 | Ontogen Corporation | Modulators of proteins with phosphotryrosine recognition units |
-
1999
- 1999-12-03 WO PCT/US1999/028694 patent/WO2000034255A1/en not_active Ceased
- 1999-12-03 WO PCT/US1999/028692 patent/WO2000033836A1/en not_active Ceased
- 1999-12-03 AU AU20398/00A patent/AU2039800A/en not_active Abandoned
- 1999-12-03 AU AU21643/00A patent/AU2164300A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000033836A9 (en) | 2001-10-04 |
| AU2164300A (en) | 2000-06-26 |
| WO2000034255A1 (en) | 2000-06-15 |
| WO2000033836A1 (en) | 2000-06-15 |
| WO2000034255A9 (en) | 2001-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |