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AU2024274559A1 - Process and intermediates for the preparation of a p2x3 inhibitor - Google Patents

Process and intermediates for the preparation of a p2x3 inhibitor

Info

Publication number
AU2024274559A1
AU2024274559A1 AU2024274559A AU2024274559A AU2024274559A1 AU 2024274559 A1 AU2024274559 A1 AU 2024274559A1 AU 2024274559 A AU2024274559 A AU 2024274559A AU 2024274559 A AU2024274559 A AU 2024274559A AU 2024274559 A1 AU2024274559 A1 AU 2024274559A1
Authority
AU
Australia
Prior art keywords
intermediates
inhibitor
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2024274559A
Inventor
Monica Bocchi
Luca CARDINALI
David C. Lathbury
Massimiliano MARI
Edoardo Mariani
Fausto Pivetti
Paolo RONCHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of AU2024274559A1 publication Critical patent/AU2024274559A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU2024274559A 2023-05-22 2024-05-21 Process and intermediates for the preparation of a p2x3 inhibitor Pending AU2024274559A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23174500.1 2023-05-22
EP23174500 2023-05-22
PCT/EP2024/063879 WO2024240728A1 (en) 2023-05-22 2024-05-21 Process and intermediates for the preparation of a p2x3 inhibitor

Publications (1)

Publication Number Publication Date
AU2024274559A1 true AU2024274559A1 (en) 2026-01-22

Family

ID=86497431

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2024274559A Pending AU2024274559A1 (en) 2023-05-22 2024-05-21 Process and intermediates for the preparation of a p2x3 inhibitor

Country Status (7)

Country Link
CN (1) CN121368584A (en)
AR (1) AR132737A1 (en)
AU (1) AU2024274559A1 (en)
IL (1) IL324769A (en)
MX (1) MX2025013808A (en)
TW (1) TW202509013A (en)
WO (1) WO2024240728A1 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2608329T3 (en) 2010-02-03 2017-04-07 Incyte Holdings Corporation Imidazo [1,2-b] [1,2,4] triazines as c-Met inhibitors
WO2016088838A1 (en) 2014-12-04 2016-06-09 塩野義製薬株式会社 Purine derivative and pharmaceutical composition thereof
CN110256418B (en) 2014-12-09 2023-01-20 拜耳公司 1, 3-thiazol-2-yl substituted benzamides
EP3976609A1 (en) 2019-05-31 2022-04-06 Chiesi Farmaceutici S.p.A. Pyridopyrimidines derivatives as p2x3 inhibitors
JP7641917B2 (en) 2019-05-31 2025-03-07 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ Aminoquinazoline Derivatives as P2X3 Inhibitors
CA3196335A1 (en) 2020-11-27 2022-06-02 Chiesi Farmaceutici S.P.A. Phthalazine derivatives as p2x3 inhibitors
KR20230113536A (en) 2020-11-27 2023-07-31 키에시 파르마슈티시 엣스. 피. 에이. (aza)quinoline 4-amine derivatives as P2X3 inhibitors
US20240025880A1 (en) 2020-11-27 2024-01-25 Chiesi Farmaceutici S.P.A. Amino quinazoline derivatives as p2x3 inhibitors

Also Published As

Publication number Publication date
IL324769A (en) 2026-01-01
AR132737A1 (en) 2025-07-23
WO2024240728A1 (en) 2024-11-28
TW202509013A (en) 2025-03-01
MX2025013808A (en) 2025-12-01
CN121368584A (en) 2026-01-20

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