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AU2024272280A1 - Preparation of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in enantiomerically enriched form by resolution process - Google Patents

Preparation of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in enantiomerically enriched form by resolution process

Info

Publication number
AU2024272280A1
AU2024272280A1 AU2024272280A AU2024272280A AU2024272280A1 AU 2024272280 A1 AU2024272280 A1 AU 2024272280A1 AU 2024272280 A AU2024272280 A AU 2024272280A AU 2024272280 A AU2024272280 A AU 2024272280A AU 2024272280 A1 AU2024272280 A1 AU 2024272280A1
Authority
AU
Australia
Prior art keywords
carbazole
carboxamide
tetrahydro
chloro
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2024272280A
Inventor
Sophie FRÖHLICH
Nicolas Tesson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AOP Orphan IP AG
Original Assignee
AOP Orphan IP AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AOP Orphan IP AG filed Critical AOP Orphan IP AG
Publication of AU2024272280A1 publication Critical patent/AU2024272280A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2024272280A 2023-05-16 2024-05-15 Preparation of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in enantiomerically enriched form by resolution process Pending AU2024272280A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23173734 2023-05-16
EP23173734.7 2023-05-16
PCT/EP2024/063346 WO2024236024A1 (en) 2023-05-16 2024-05-15 Preparation of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in enantiomerically enriched form by resolution process

Publications (1)

Publication Number Publication Date
AU2024272280A1 true AU2024272280A1 (en) 2025-11-06

Family

ID=86386967

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2024272280A Pending AU2024272280A1 (en) 2023-05-16 2024-05-15 Preparation of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in enantiomerically enriched form by resolution process

Country Status (6)

Country Link
CN (1) CN121127454A (en)
AR (1) AR132691A1 (en)
AU (1) AU2024272280A1 (en)
MX (1) MX2025013306A (en)
TW (1) TW202515536A (en)
WO (1) WO2024236024A1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2538759C (en) 2003-09-12 2015-11-03 Elixir Pharmaceuticals, Inc. Substituted heterocyclic compounds as sirtuin inhitibitors
US20060074124A1 (en) * 2003-09-12 2006-04-06 Andrew Napper Methods of treating a disorder
WO2008019825A1 (en) * 2006-08-14 2008-02-21 Santhera Pharmaceuticals (Schweiz) Ag Use of tricyclic indole derivatives for the treatment of muscular diseases
WO2010054382A1 (en) * 2008-11-10 2010-05-14 Elixir Pharmaceuticals, Inc. Compounds, compositions, and methods for treating malaria or leishmaniasis
AR088377A1 (en) 2011-10-20 2014-05-28 Siena Biotech Spa PROCESS FOR THE PREPARATION OF 6-CHLORINE-2,3,4,9-TETRAHIDRO-1H-CARBAZOL-1-CARBOXAMIDE AND INTERMEDIATE COMPOUNDS OF THIS

Also Published As

Publication number Publication date
WO2024236024A1 (en) 2024-11-21
AR132691A1 (en) 2025-07-23
CN121127454A (en) 2025-12-12
MX2025013306A (en) 2025-12-01
TW202515536A (en) 2025-04-16

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