AU2016219676A1 - Anti-activin A antibodies and uses thereof - Google Patents
Anti-activin A antibodies and uses thereofInfo
- Publication number
- AU2016219676A1 AU2016219676A1 AU2016219676A AU2016219676A AU2016219676A1 AU 2016219676 A1 AU2016219676 A1 AU 2016219676A1 AU 2016219676 A AU2016219676 A AU 2016219676A AU 2016219676 A AU2016219676 A AU 2016219676A AU 2016219676 A1 AU2016219676 A1 AU 2016219676A1
- Authority
- AU
- Australia
- Prior art keywords
- antibodies
- activin
- derivatives
- polypeptides
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000488 activin Substances 0.000 title abstract 2
- 108010023082 activin A Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 206010006895 Cachexia Diseases 0.000 abstract 1
- 102000023732 binding proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000002710 gonadal effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Abstract The disclosure provides compositions and methods relating to or derived from anti activin A binding proteins, including antibodies. In particular embodiments, the disclosure provides fully human, humanized, and chimeric anti-activin A antibodies that bind human activin A, activin A-binding fragments and derivatives of such antibodies, and activin A-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having activin A related disorders or conditions including cachexia related to gonadal cancer, other cancers, rheumatoid arthritis, and other diseases.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2016219676A AU2016219676A1 (en) | 2006-09-08 | 2016-08-25 | Anti-activin A antibodies and uses thereof |
| AU2018201242A AU2018201242B2 (en) | 2006-09-08 | 2018-02-21 | Anti-activin A antibodies and uses thereof |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60/843,430 | 2006-09-08 | ||
| US60/956,653 | 2007-08-17 | ||
| AU2012265564A AU2012265564B2 (en) | 2006-09-08 | 2012-12-18 | Anti-activin A antibodies and uses thereof |
| AU2016219676A AU2016219676A1 (en) | 2006-09-08 | 2016-08-25 | Anti-activin A antibodies and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012265564A Division AU2012265564B2 (en) | 2006-09-08 | 2012-12-18 | Anti-activin A antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018201242A Division AU2018201242B2 (en) | 2006-09-08 | 2018-02-21 | Anti-activin A antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2016219676A1 true AU2016219676A1 (en) | 2016-09-15 |
Family
ID=56898953
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016219676A Abandoned AU2016219676A1 (en) | 2006-09-08 | 2016-08-25 | Anti-activin A antibodies and uses thereof |
| AU2018201242A Active AU2018201242B2 (en) | 2006-09-08 | 2018-02-21 | Anti-activin A antibodies and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018201242A Active AU2018201242B2 (en) | 2006-09-08 | 2018-02-21 | Anti-activin A antibodies and uses thereof |
Country Status (1)
| Country | Link |
|---|---|
| AU (2) | AU2016219676A1 (en) |
-
2016
- 2016-08-25 AU AU2016219676A patent/AU2016219676A1/en not_active Abandoned
-
2018
- 2018-02-21 AU AU2018201242A patent/AU2018201242B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018201242B2 (en) | 2019-10-17 |
| AU2018201242A1 (en) | 2018-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |