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AU2003221505A1 - Sample carrier comprising integrated optics - Google Patents

Sample carrier comprising integrated optics

Info

Publication number
AU2003221505A1
AU2003221505A1 AU2003221505A AU2003221505A AU2003221505A1 AU 2003221505 A1 AU2003221505 A1 AU 2003221505A1 AU 2003221505 A AU2003221505 A AU 2003221505A AU 2003221505 A AU2003221505 A AU 2003221505A AU 2003221505 A1 AU2003221505 A1 AU 2003221505A1
Authority
AU
Australia
Prior art keywords
sample carrier
integrated optics
sample
light beam
integrated optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003221505A
Inventor
Johan-Valentin Kahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ibidi GmbH
Original Assignee
Ibidi GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibidi GmbH filed Critical Ibidi GmbH
Publication of AU2003221505A1 publication Critical patent/AU2003221505A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24—Coupling light guides
    • G02B6/26—Optical coupling means
    • G02B6/32—Optical coupling means having lens focusing means positioned between opposed fibre ends
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24—Coupling light guides
    • G02B6/26—Optical coupling means
    • G02B6/32—Optical coupling means having lens focusing means positioned between opposed fibre ends
    • G02B6/327—Optical coupling means having lens focusing means positioned between opposed fibre ends with angled interfaces to reduce reflections
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Microscoopes, Condenser (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The sample carrier (1) comprises at least one integrated optical component to guide and/or modulate a light beam. The sample holder (2) is divided into two channels, and an excitation light beam (3) is deflected by the total reflection of the integrated optical zones (4) to illuminate different samples (6). A fluorescent signal (8) from the sample can be formed as an image by a lens or directly at a camera or photo-diode.
AU2003221505A 2002-03-18 2003-03-18 Sample carrier comprising integrated optics Abandoned AU2003221505A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02006113A EP1347284B1 (en) 2002-03-18 2002-03-18 Sample holder with integrated optics
EP02006113.1 2002-03-18
PCT/EP2003/002833 WO2003078978A1 (en) 2002-03-18 2003-03-18 Sample carrier comprising integrated optics

Publications (1)

Publication Number Publication Date
AU2003221505A1 true AU2003221505A1 (en) 2003-09-29

Family

ID=27771853

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003221505A Abandoned AU2003221505A1 (en) 2002-03-18 2003-03-18 Sample carrier comprising integrated optics

Country Status (5)

Country Link
EP (1) EP1347284B1 (en)
AT (1) ATE383572T1 (en)
AU (1) AU2003221505A1 (en)
DE (1) DE50211516D1 (en)
WO (1) WO2003078978A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007077218A1 (en) * 2006-01-03 2007-07-12 Inverness Medical Switzerland Gmbh An optical system; an optical chip for an optical system and a method of using an optical chip for an analytical operation
US11940413B2 (en) 2007-02-05 2024-03-26 IsoPlexis Corporation Methods and devices for sequencing nucleic acids in smaller batches
DE112008000363B4 (en) 2007-02-05 2021-12-02 Qiagen Sciences, LLC (n.d.Ges.d. Staates Delaware) Device for detection and its use
US11035823B2 (en) 2009-03-17 2021-06-15 Qiagen Sciences, Llc Methods and devices for sequencing nucleic acids in smaller batches
US8481259B2 (en) 2007-02-05 2013-07-09 Intelligent Bio-Systems, Inc. Methods and devices for sequencing nucleic acids in smaller batches
AT504669B1 (en) * 2007-05-15 2008-07-15 Arc Austrian Res Centers Gmbh Sample support for use in recording unit during analyzing of hybridization reactions, has plano-convex cylinder lens provided for collimation and formation of laser band, which is irradiated through side surface in support
DE102007033124B4 (en) * 2007-07-16 2012-12-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Device for the optical detection of substances in a liquid or gaseous medium
US8300993B2 (en) * 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
DE102009025073A1 (en) * 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optical sensor
DE102010038431A1 (en) * 2010-07-26 2012-01-26 Diasys Diagnostic Systems Gmbh Measuring cassette and measuring device for the detection of target molecules in a liquid sample by measuring fluorescence emission after excitation in the evanescent field
DE102010041426A1 (en) * 2010-09-27 2012-05-03 Siemens Aktiengesellschaft Measuring unit for optical estimation of liquid for determining concentration of analytes, has two excitation light paths and device for adjusting wavelength or intensity or polarization direction
TWI569037B (en) * 2014-04-25 2017-02-01 A fluorescent vehicle for fluorescent microscopes
DE102017115661A1 (en) * 2017-07-12 2019-01-17 Endress+Hauser Conducta Gmbh+Co. Kg Optical sensor
DE102018202588A1 (en) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optical sensor device and a method for producing an optical sensor device
DE102018202591A1 (en) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optical system and method of making an optical system
DE102018133037B4 (en) * 2018-12-20 2021-02-25 Leibniz-Institut für Photonische Technologien e. V. Arrangement and method for detecting optical properties of a sample, in particular for the selective detection of biological molecules and for reading out a molecule occupancy
DE102021133357A1 (en) 2021-12-15 2023-06-15 Endress+Hauser Conducta Gmbh+Co. Kg Sensor element, sensor system and method for manufacturing the sensor element

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3915920A1 (en) * 1989-05-16 1990-11-22 Messerschmitt Boelkow Blohm Micro-mechanical structures for storing and testing substances - e.g. for disease diagnosis, is made of inert material, e.g. glass, and has defined pattern of depressions, cavities, etc.
DE59109246D1 (en) * 1990-05-03 2003-04-03 Hoffmann La Roche Micro-optical sensor
DE59405534D1 (en) * 1993-07-02 1998-04-30 Inst Molekulare Biolog E V SAMPLE CARRIER AND ITS USE
DE10024132B4 (en) * 2000-01-28 2007-03-22 Leica Microsystems Cms Gmbh Arrangement for detecting fluorescent light of several sample points

Also Published As

Publication number Publication date
EP1347284A1 (en) 2003-09-24
WO2003078978A1 (en) 2003-09-25
ATE383572T1 (en) 2008-01-15
EP1347284B1 (en) 2008-01-09
DE50211516D1 (en) 2008-02-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase