AU2003218629A1 - A building block forming a c-c or a c-hetero atom bond uponreaction - Google Patents
A building block forming a c-c or a c-hetero atom bond uponreactionInfo
- Publication number
- AU2003218629A1 AU2003218629A1 AU2003218629A AU2003218629A AU2003218629A1 AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1 AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1
- Authority
- AU
- Australia
- Prior art keywords
- uponreaction
- building block
- hetero atom
- block forming
- atom bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36405602P | 2002-03-15 | 2002-03-15 | |
DKPA200200415 | 2002-03-15 | ||
US60/364,056 | 2002-03-15 | ||
DKPA20020415 | 2002-03-15 | ||
US43442302P | 2002-12-19 | 2002-12-19 | |
DKPA200201950 | 2002-12-19 | ||
US60/434,423 | 2002-12-19 | ||
DKPA200201950 | 2002-12-19 | ||
PCT/DK2003/000176 WO2003078446A2 (en) | 2002-03-15 | 2003-03-14 | A building block forming a c-c or a c-hetero atom bond upon reaction |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2003218629A1 true AU2003218629A1 (en) | 2003-09-29 |
Family
ID=28046589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003218629A Abandoned AU2003218629A1 (en) | 2002-03-15 | 2003-03-14 | A building block forming a c-c or a c-hetero atom bond uponreaction |
Country Status (4)
Country | Link |
---|---|
US (1) | US20050247001A1 (en) |
EP (1) | EP1487850A2 (en) |
AU (1) | AU2003218629A1 (en) |
WO (1) | WO2003078446A2 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7070928B2 (en) | 2001-03-19 | 2006-07-04 | President And Fellows Of Harvard College | Evolving new molecular function |
US7727713B2 (en) | 2001-06-20 | 2010-06-01 | Nuevolution A/S | Templated molecules and methods for using such molecules |
US7413854B2 (en) | 2002-03-15 | 2008-08-19 | Nuevolution A/S | Method for synthesising templated molecules |
EP1539980B1 (en) | 2002-08-01 | 2016-02-17 | Nuevolution A/S | Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules |
US7491494B2 (en) | 2002-08-19 | 2009-02-17 | President And Fellows Of Harvard College | Evolving new molecular function |
CN106337046B (en) | 2002-10-30 | 2021-03-23 | 纽韦卢森公司 | Method for synthesizing bifunctional complexes |
US9121110B2 (en) | 2002-12-19 | 2015-09-01 | Nuevolution A/S | Quasirandom structure and function guided synthesis methods |
US20070026397A1 (en) | 2003-02-21 | 2007-02-01 | Nuevolution A/S | Method for producing second-generation library |
US7915201B2 (en) | 2003-03-20 | 2011-03-29 | Nuevolution A/S | Ligational encoding of small molecules |
US11118215B2 (en) | 2003-09-18 | 2021-09-14 | Nuevolution A/S | Method for obtaining structural information concerning an encoded molecule and method for selecting compounds |
US7972994B2 (en) | 2003-12-17 | 2011-07-05 | Glaxosmithkline Llc | Methods for synthesis of encoded libraries |
NZ547723A (en) | 2003-12-17 | 2009-09-25 | Praecis Pharm Inc | Methods for synthesis of encoded libraries |
ATE447020T1 (en) | 2004-03-22 | 2009-11-15 | Nuevolution As | LIGATION CODING USING OLIGONUCLEOTIDE BUILDING BLOCKS |
EP1940755A2 (en) | 2005-10-28 | 2008-07-09 | Praecis Pharmaceuticals Inc. | Methods for identifying compounds of interest using encoded libraries |
DK2341140T3 (en) | 2005-12-01 | 2017-11-06 | Nuevolution As | Method for enzymatic coding by efficient synthesis of large libraries |
EA028985B1 (en) | 2009-02-13 | 2018-01-31 | Икс-Чем, Инк. | Methods for identifying compounds of dna-encoded libraries |
DK2558577T3 (en) | 2010-04-16 | 2019-04-01 | Nuevolution As | Bi-functional complexes and methods for the preparation and use of such complexes |
DK3351631T3 (en) | 2011-09-07 | 2021-01-18 | X Chem Inc | METHODS FOR LABELING DNA-CODED LIBRARIES |
NZ739931A (en) | 2012-07-13 | 2019-08-30 | X Chem Inc | Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases |
JP7283727B2 (en) | 2016-06-16 | 2023-05-30 | ヘイスタック サイエンシィズ コーポレーション | Oligonucleotides Directed and Recorded for Combinatorial Synthesis of Code Probe Molecules |
EP3619340A4 (en) * | 2017-05-02 | 2021-01-20 | Haystack Sciences Corporation | MOLECULES FOR THE VERIFICATION OF OLIGONUCLEOTIDE DIRECTED COMBINATIONAL SYNTHESIS AND METHOD OF MANUFACTURING AND USING THEREOF |
PT3853234T (en) | 2018-09-18 | 2025-07-29 | Nikang Therapeutics Inc | Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3763281A (en) * | 1970-06-26 | 1973-10-02 | Stauffer Chemical Co | Ureidoalkylphosphonates |
US4822731A (en) * | 1986-01-09 | 1989-04-18 | Cetus Corporation | Process for labeling single-stranded nucleic acids and hybridizaiton probes |
US5770358A (en) * | 1991-09-18 | 1998-06-23 | Affymax Technologies N.V. | Tagged synthetic oligomer libraries |
US5639603A (en) * | 1991-09-18 | 1997-06-17 | Affymax Technologies N.V. | Synthesizing and screening molecular diversity |
US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
DE69433010T2 (en) * | 1993-04-12 | 2004-06-09 | Northwestern University, Evanston | METHOD FOR PRESENTING OLIGONUCLEOTIDES |
US5681943A (en) * | 1993-04-12 | 1997-10-28 | Northwestern University | Method for covalently linking adjacent oligonucleotides |
US5473060A (en) * | 1993-07-02 | 1995-12-05 | Lynx Therapeutics, Inc. | Oligonucleotide clamps having diagnostic applications |
US5571903A (en) * | 1993-07-09 | 1996-11-05 | Lynx Therapeutics, Inc. | Auto-ligating oligonucleotide compounds |
US6165778A (en) * | 1993-11-02 | 2000-12-26 | Affymax Technologies N.V. | Reaction vessel agitation apparatus |
US5503805A (en) * | 1993-11-02 | 1996-04-02 | Affymax Technologies N.V. | Apparatus and method for parallel coupling reactions |
US5605793A (en) * | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
US5843650A (en) * | 1995-05-01 | 1998-12-01 | Segev; David | Nucleic acid detection and amplification by chemical linkage of oligonucleotides |
US5830658A (en) * | 1995-05-31 | 1998-11-03 | Lynx Therapeutics, Inc. | Convergent synthesis of branched and multiply connected macromolecular structures |
US5780613A (en) * | 1995-08-01 | 1998-07-14 | Northwestern University | Covalent lock for self-assembled oligonucleotide constructs |
EP0971946B1 (en) * | 1997-01-21 | 2006-07-05 | The General Hospital Corporation | Selection of proteins using rna-protein fusions |
PT985032E (en) * | 1997-05-28 | 2004-02-27 | Discerna Ltd | RIBOSOMIC COMPLEXES AS SELECTIVE PARTICLES FOR IN VITRO PRESENTATION AND EVOLUTION OF PROTEINS |
GB9815163D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds |
EP1073730A1 (en) * | 1998-04-17 | 2001-02-07 | Whitehead For Biomedical Research | Use of a ribozyme to join nucleic acids and peptides |
PT1196637E (en) * | 1999-07-27 | 2007-07-04 | Adnexus Therapeutics Inc | Peptide acceptor ligation methods |
DE60002821T2 (en) * | 1999-08-27 | 2004-05-06 | Japan Science And Technology Corp., Kawaguchi | REVERSIBLE PHOTOCOUPLING NUCLEIC ACID AND PHOSPHORAMIDITE |
US7070928B2 (en) * | 2001-03-19 | 2006-07-04 | President And Fellows Of Harvard College | Evolving new molecular function |
-
2003
- 2003-03-14 WO PCT/DK2003/000176 patent/WO2003078446A2/en not_active Application Discontinuation
- 2003-03-14 AU AU2003218629A patent/AU2003218629A1/en not_active Abandoned
- 2003-03-14 US US10/507,829 patent/US20050247001A1/en not_active Abandoned
- 2003-03-14 EP EP03711855A patent/EP1487850A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US20050247001A1 (en) | 2005-11-10 |
WO2003078446A3 (en) | 2003-12-31 |
EP1487850A2 (en) | 2004-12-22 |
WO2003078446A2 (en) | 2003-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |