AU2003218629A1 - A building block forming a c-c or a c-hetero atom bond uponreaction - Google Patents
A building block forming a c-c or a c-hetero atom bond uponreactionInfo
- Publication number
- AU2003218629A1 AU2003218629A1 AU2003218629A AU2003218629A AU2003218629A1 AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1 AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1
- Authority
- AU
- Australia
- Prior art keywords
- uponreaction
- building block
- hetero atom
- block forming
- atom bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36405602P | 2002-03-15 | 2002-03-15 | |
| DKPA20020415 | 2002-03-15 | ||
| US60/364,056 | 2002-03-15 | ||
| DKPA200200415 | 2002-03-15 | ||
| US43442302P | 2002-12-19 | 2002-12-19 | |
| US60/434,423 | 2002-12-19 | ||
| DKPA200201950 | 2002-12-19 | ||
| DKPA200201950 | 2002-12-19 | ||
| PCT/DK2003/000176 WO2003078446A2 (en) | 2002-03-15 | 2003-03-14 | A building block forming a c-c or a c-hetero atom bond upon reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003218629A1 true AU2003218629A1 (en) | 2003-09-29 |
Family
ID=28046589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003218629A Abandoned AU2003218629A1 (en) | 2002-03-15 | 2003-03-14 | A building block forming a c-c or a c-hetero atom bond uponreaction |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20050247001A1 (en) |
| EP (1) | EP1487850A2 (en) |
| AU (1) | AU2003218629A1 (en) |
| WO (1) | WO2003078446A2 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2332896A3 (en) | 2001-03-19 | 2012-09-26 | President and Fellows of Harvard College | Evolving new molecular function |
| WO2002102820A1 (en) | 2001-06-20 | 2002-12-27 | Nuevolution A/S | Nucleoside derivatives for library preparation |
| DE60324778D1 (en) | 2002-03-15 | 2009-01-02 | Nuevolution As | AN IMPROVED METHOD FOR SYNTHESIS OF MATTRESS-RELATED MOLECULES |
| EP1539980B1 (en) | 2002-08-01 | 2016-02-17 | Nuevolution A/S | Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules |
| CA2495881C (en) | 2002-08-19 | 2014-07-08 | The President And Fellows Of Harvard College | Evolving new molecular function |
| CN1720331B (en) | 2002-10-30 | 2013-01-02 | 纽韦卢森公司 | Method for synthesizing bifunctional complexes |
| AU2003291964A1 (en) | 2002-12-19 | 2004-07-14 | Nuevolution A/S | Quasirandom structure and function guided synthesis methods |
| EP1597395A2 (en) | 2003-02-21 | 2005-11-23 | Nuevolution A/S | Method for producing second-generation library |
| DE602004019764D1 (en) | 2003-03-20 | 2009-04-16 | Nuevolution As | LIGATION-RELATED CODING OF SMALL MOLECULES |
| DK1670939T3 (en) | 2003-09-18 | 2010-03-01 | Nuevolution As | Method for obtaining structural information on a coded molecule and method for selecting compounds |
| BRPI0417830B1 (en) | 2003-12-17 | 2021-02-17 | Praecis Pharmaceuticals Inc | methods for synthesizing a molecule comprising a functional portion operably linked to a coding oligonucleotide |
| US7972994B2 (en) | 2003-12-17 | 2011-07-05 | Glaxosmithkline Llc | Methods for synthesis of encoded libraries |
| US7704925B2 (en) | 2004-03-22 | 2010-04-27 | Nuevolution A/S | Ligational encoding using building block oligonucleotides |
| EP2368868A1 (en) | 2005-10-28 | 2011-09-28 | Praecis Pharmaceuticals Inc. | Methods for identifying compounds of interest using encoded libraries |
| DK3018206T3 (en) * | 2005-12-01 | 2021-11-15 | Nuevolution As | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES |
| DK3211126T3 (en) | 2009-02-13 | 2020-12-21 | X Chem Inc | METHODS FOR FORMING AND SCREENING DNA-CODED LIBRARIES |
| EP2558577B1 (en) | 2010-04-16 | 2018-12-12 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
| EP3351631B1 (en) | 2011-09-07 | 2020-11-04 | X-Chem, Inc. | Methods for tagging dna-encoded libraries |
| DK3392338T3 (en) | 2012-07-13 | 2021-02-01 | X Chem Inc | DNA-CODED LIBRARIES WITH CODING OLIGONUCLEOTID BINDS WHICH CANNOT BE READ BY POLYMERASES |
| CN115820806A (en) | 2016-06-16 | 2023-03-21 | 哈斯达克科学公司 | Combinatorial synthesis of oligonucleotide-guided and documented encoded probe molecules |
| WO2018204420A1 (en) * | 2017-05-02 | 2018-11-08 | Haystack Sciences Corporation | Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same |
| DK3853234T3 (en) | 2018-09-18 | 2025-07-21 | Nikang Therapeutics Inc | FUSIONED TRICYCLIC RING DERIVATIVES AS SRC HOMOLOGY 2-PHOSPHATASE INHIBITORS |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3763281A (en) * | 1970-06-26 | 1973-10-02 | Stauffer Chemical Co | Ureidoalkylphosphonates |
| US4822731A (en) * | 1986-01-09 | 1989-04-18 | Cetus Corporation | Process for labeling single-stranded nucleic acids and hybridizaiton probes |
| US5770358A (en) * | 1991-09-18 | 1998-06-23 | Affymax Technologies N.V. | Tagged synthetic oligomer libraries |
| US5639603A (en) * | 1991-09-18 | 1997-06-17 | Affymax Technologies N.V. | Synthesizing and screening molecular diversity |
| US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| ATE246702T1 (en) * | 1993-04-12 | 2003-08-15 | Univ Northwestern | METHOD FOR PREPARING OLIGONUCLEOTIDES |
| US5681943A (en) * | 1993-04-12 | 1997-10-28 | Northwestern University | Method for covalently linking adjacent oligonucleotides |
| US5473060A (en) * | 1993-07-02 | 1995-12-05 | Lynx Therapeutics, Inc. | Oligonucleotide clamps having diagnostic applications |
| US5571903A (en) * | 1993-07-09 | 1996-11-05 | Lynx Therapeutics, Inc. | Auto-ligating oligonucleotide compounds |
| US6165778A (en) * | 1993-11-02 | 2000-12-26 | Affymax Technologies N.V. | Reaction vessel agitation apparatus |
| US5503805A (en) * | 1993-11-02 | 1996-04-02 | Affymax Technologies N.V. | Apparatus and method for parallel coupling reactions |
| US5605793A (en) * | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5843650A (en) * | 1995-05-01 | 1998-12-01 | Segev; David | Nucleic acid detection and amplification by chemical linkage of oligonucleotides |
| US5830658A (en) * | 1995-05-31 | 1998-11-03 | Lynx Therapeutics, Inc. | Convergent synthesis of branched and multiply connected macromolecular structures |
| US5780613A (en) * | 1995-08-01 | 1998-07-14 | Northwestern University | Covalent lock for self-assembled oligonucleotide constructs |
| ATE332368T1 (en) * | 1997-01-21 | 2006-07-15 | Gen Hospital Corp | SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS |
| ES2209145T5 (en) * | 1997-05-28 | 2009-10-30 | Crescendo Biologics Ltd. | RIBOSOME COMPLEXES AS SELECTION PARTICLES FOR IN VITRO DEVELOPMENT AND PROTEIN EVOLUTION. |
| GB9815163D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds |
| EP1073730A1 (en) * | 1998-04-17 | 2001-02-07 | Whitehead For Biomedical Research | Use of a ribozyme to join nucleic acids and peptides |
| KR20020033743A (en) * | 1999-07-27 | 2002-05-07 | 추후기재 | Peptide acceptor ligation methods |
| US6593088B1 (en) * | 1999-08-27 | 2003-07-15 | Japan Science And Technology Corporation | Reversible photocoupling nucleic acid and phosphoroamidite |
| EP2332896A3 (en) * | 2001-03-19 | 2012-09-26 | President and Fellows of Harvard College | Evolving new molecular function |
-
2003
- 2003-03-14 AU AU2003218629A patent/AU2003218629A1/en not_active Abandoned
- 2003-03-14 US US10/507,829 patent/US20050247001A1/en not_active Abandoned
- 2003-03-14 EP EP03711855A patent/EP1487850A2/en not_active Withdrawn
- 2003-03-14 WO PCT/DK2003/000176 patent/WO2003078446A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1487850A2 (en) | 2004-12-22 |
| WO2003078446A2 (en) | 2003-09-25 |
| US20050247001A1 (en) | 2005-11-10 |
| WO2003078446A3 (en) | 2003-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |