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AU2003201559A1 - Multispecific binding molecules - Google Patents

Multispecific binding molecules

Info

Publication number
AU2003201559A1
AU2003201559A1 AU2003201559A AU2003201559A AU2003201559A1 AU 2003201559 A1 AU2003201559 A1 AU 2003201559A1 AU 2003201559 A AU2003201559 A AU 2003201559A AU 2003201559 A AU2003201559 A AU 2003201559A AU 2003201559 A1 AU2003201559 A1 AU 2003201559A1
Authority
AU
Australia
Prior art keywords
binding molecules
multispecific binding
multispecific
molecules
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003201559A
Other versions
AU2003201559A8 (en
Inventor
William Herman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/CA2002/000317 external-priority patent/WO2002072141A2/en
Priority claimed from CA 2397169 external-priority patent/CA2397169A1/en
Priority claimed from CA 2402930 external-priority patent/CA2402930A1/en
Application filed by Individual filed Critical Individual
Publication of AU2003201559A8 publication Critical patent/AU2003201559A8/en
Publication of AU2003201559A1 publication Critical patent/AU2003201559A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626Diabody or triabody
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
AU2003201559A 2002-01-14 2003-01-14 Multispecific binding molecules Abandoned AU2003201559A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CA2368708 2002-01-14
CA2,368,708 2002-01-14
PCT/CA2002/000317 WO2002072141A2 (en) 2001-03-09 2002-03-11 Targeted ligands
AU2002240751 2002-03-11
CA 2397169 CA2397169A1 (en) 2002-08-13 2002-08-13 Targeted ligands
CA2,397,169 2002-08-13
CA 2402930 CA2402930A1 (en) 2002-09-19 2002-09-19 Targeted ligands
CA2,402,930 2002-09-19
PCT/CA2003/000044 WO2003057732A2 (en) 2002-01-14 2003-01-14 Multispecific binding molecules

Publications (2)

Publication Number Publication Date
AU2003201559A8 AU2003201559A8 (en) 2003-07-24
AU2003201559A1 true AU2003201559A1 (en) 2003-07-24

Family

ID=27426779

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003201559A Abandoned AU2003201559A1 (en) 2002-01-14 2003-01-14 Multispecific binding molecules

Country Status (4)

Country Link
EP (1) EP1497331A2 (en)
AU (1) AU2003201559A1 (en)
CA (1) CA2513287A1 (en)
WO (1) WO2003057732A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101608083B1 (en) 2005-01-25 2016-04-01 씨티아이 바이오파마 코포레이션 Conjugates of biologically active proteins having a modified in vivo half-life
AU2018281871B2 (en) * 2017-06-07 2022-07-28 Philogen S.P.A. Vascular endothelial growth factor/anti-fibronectin antibody fusion proteins
WO2022036495A1 (en) 2020-08-17 2022-02-24 Utc Therapeutics Inc. Lymphocytes-antigen presenting cells co-stimulators and uses thereof
MX2023001962A (en) 2020-08-19 2023-04-26 Xencor Inc Anti-cd28 and/or anti-b7h3 compositions.
JP2025508827A (en) 2022-02-23 2025-04-10 ゼンコア インコーポレイテッド Anti-CD28 x anti-PSMA antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0739904A1 (en) * 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
WO1992005282A1 (en) * 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
DE69719529T2 (en) * 1996-10-17 2003-12-11 Immunomedics, Inc. NONANTANT TOXIN CONJUGATE AND FUSION PROTEIN IN AN INTERNALIZING RECEPTOR SYSTEM
AU2226799A (en) * 1998-01-15 1999-08-02 Center For Molecular Medicine And Immunology Antibody/receptor targeting moiety for enhanced delivery of armed ligand
WO2000018806A1 (en) * 1998-09-25 2000-04-06 Horst Lindhofer Bispecific and trispecific antibodies which specifically react with inducible surface antigens as operational target structures
CN101712721A (en) * 2000-06-05 2010-05-26 阿尔托生物科学有限公司 T cell receptor fusions and conjugates and methods of use thereof
AU2002240751A1 (en) * 2001-03-09 2002-09-24 William Herman Targeted ligands

Also Published As

Publication number Publication date
AU2003201559A8 (en) 2003-07-24
CA2513287A1 (en) 2003-07-17
WO2003057732A2 (en) 2003-07-17
EP1497331A2 (en) 2005-01-19
WO2003057732A3 (en) 2003-10-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase