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AU2003298611A1 - Mixed lineage kinase modulators - Google Patents

Mixed lineage kinase modulators

Info

Publication number
AU2003298611A1
AU2003298611A1 AU2003298611A AU2003298611A AU2003298611A1 AU 2003298611 A1 AU2003298611 A1 AU 2003298611A1 AU 2003298611 A AU2003298611 A AU 2003298611A AU 2003298611 A AU2003298611 A AU 2003298611A AU 2003298611 A1 AU2003298611 A1 AU 2003298611A1
Authority
AU
Australia
Prior art keywords
mixed lineage
kinase modulators
lineage kinase
modulators
mixed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003298611A
Inventor
Arindam Chatterjee
Theodore Junior Goodson
Mary Margaret Mader
John Eldon Toth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2003298611A1 publication Critical patent/AU2003298611A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2003298611A 2002-11-21 2003-11-12 Mixed lineage kinase modulators Abandoned AU2003298611A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42832202P 2002-11-21 2002-11-21
US60/428,322 2002-11-21
PCT/US2003/035036 WO2004048383A1 (en) 2002-11-21 2003-11-12 Mixed lineage kinase modulators

Publications (1)

Publication Number Publication Date
AU2003298611A1 true AU2003298611A1 (en) 2004-06-18

Family

ID=32393381

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003298611A Abandoned AU2003298611A1 (en) 2002-11-21 2003-11-12 Mixed lineage kinase modulators

Country Status (5)

Country Link
EP (1) EP1567528A1 (en)
JP (1) JP2006522735A (en)
AU (1) AU2003298611A1 (en)
CA (1) CA2506799A1 (en)
WO (1) WO2004048383A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80571C2 (en) 2002-11-22 2007-10-10 Lilly Co Eli Quinolinyl-pyrrolopyrazoles
CR9465A (en) * 2005-03-25 2008-06-19 Surface Logix Inc PHARMACOCINETICALLY IMPROVED COMPOUNDS
SI1910370T1 (en) 2005-07-22 2015-06-30 Eli Lilly And Company A pyridin quinolin substituted pyrrolo (1,2-b) pyrazole monohydrate as tgf-beta inhibitor
US7919519B2 (en) 2005-11-23 2011-04-05 Epix Pharmaceuticals Inc. S1P receptor modulating compounds and use thereof
EP1965807A4 (en) * 2005-11-23 2010-10-27 Epix Delaware Inc S1p receptor modulating compounds and use thereof
AR060050A1 (en) 2006-03-21 2008-05-21 Epix Delaware Inc MODULATING COMPOUNDS OF THE S1P RECEIVER AND USE OF THE SAME
NZ623002A (en) 2006-06-26 2015-08-28 Akebia Therapeutics Inc Prolyl hydroxylase inhibitors and methods of use
JP5191497B2 (en) * 2007-03-21 2013-05-08 エピックス ファーマシューティカルズ,インコーポレイテッド S1P receptor modulating compounds and uses thereof
JP2010540438A (en) 2007-09-20 2010-12-24 アムジエン・インコーポレーテツド 1- (4-Benzylbenzamido) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as S1P receptor modulators for treating immune disorders
DE102009001438A1 (en) 2009-03-10 2010-09-16 Bayer Schering Pharma Aktiengesellschaft New carbonylamino-substituted anilino-pyrimidine compounds are tyrosine kinase-2 inhibitors, useful for treating diseases associated with inflammatory conditions e.g. bronchitis, rheumatoid arthritis, psoriasis and Guillain Barre syndrome
DE102009015070A1 (en) 2009-03-30 2010-10-14 Bayer Schering Pharma Aktiengesellschaft New phenyl-pyrimidin-2-yl-amine compounds are tyrosine kinase 2 inhibitors useful for treating e.g. rheumatoid arthritis, Crohn's disease, asthma, multiple sclerosis, adult respiratory distress syndrome, allergic alveolitis and uveitis
US20120329836A1 (en) 2011-06-06 2012-12-27 The Ohio State University Methods for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (en) 2011-06-06 2018-03-17
SI3007695T1 (en) 2013-06-13 2024-04-30 Akebia Therapeutics, Inc. Compositions and methods for treating anemia
JP2018502882A (en) 2015-01-23 2018-02-01 アケビア セラピューティクス インコーポレイテッドAkebia Therapeutics Inc. Solid form of 2- (5- (3-fluorophenyl) -3-hydroxypicolinamide) acetic acid, its composition and use
EP3277673B1 (en) 2015-04-01 2022-05-04 Rigel Pharmaceuticals, Inc. Tgf-beta inhibitors
HRP20211862T1 (en) 2015-04-01 2022-03-04 Akebia Therapeutics, Inc. PREPARATIONS FOR AND PROCEDURES FOR THE TREATMENT OF ANEMIA
CN107663206B (en) 2016-07-29 2021-06-18 上海璎黎药业有限公司 Nitrogen-containing aromatic heterocyclic compound, its preparation method, pharmaceutical composition and application
CN110066277B (en) 2018-01-24 2021-07-23 上海璎黎药业有限公司 Aromatic heterocyclic substituted olefin compound, preparation method, pharmaceutical composition and application thereof
CN110066276B (en) 2018-01-24 2020-09-18 上海璎黎药业有限公司 Aromatic heterocyclic compound, intermediate thereof, preparation method, pharmaceutical composition and application
TWI822776B (en) 2018-05-09 2023-11-21 美商阿克比治療有限公司 Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
CN114437082B (en) * 2020-11-06 2025-04-04 江苏先声药业有限公司 Quinoline compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
CZ303808B6 (en) * 2001-05-24 2013-05-09 Eli Lilly And Company Novel pyrrole derivatives as pharmaceutical agents

Also Published As

Publication number Publication date
WO2004048383A1 (en) 2004-06-10
CA2506799A1 (en) 2004-06-10
JP2006522735A (en) 2006-10-05
EP1567528A1 (en) 2005-08-31

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase