AU2003298611A1 - Mixed lineage kinase modulators - Google Patents
Mixed lineage kinase modulatorsInfo
- Publication number
- AU2003298611A1 AU2003298611A1 AU2003298611A AU2003298611A AU2003298611A1 AU 2003298611 A1 AU2003298611 A1 AU 2003298611A1 AU 2003298611 A AU2003298611 A AU 2003298611A AU 2003298611 A AU2003298611 A AU 2003298611A AU 2003298611 A1 AU2003298611 A1 AU 2003298611A1
- Authority
- AU
- Australia
- Prior art keywords
- mixed lineage
- kinase modulators
- lineage kinase
- modulators
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102100025180 Mitogen-activated protein kinase kinase kinase 12 Human genes 0.000 title 1
- 108090001035 mitogen-activated protein kinase kinase kinase 12 Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42832202P | 2002-11-21 | 2002-11-21 | |
| US60/428,322 | 2002-11-21 | ||
| PCT/US2003/035036 WO2004048383A1 (en) | 2002-11-21 | 2003-11-12 | Mixed lineage kinase modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003298611A1 true AU2003298611A1 (en) | 2004-06-18 |
Family
ID=32393381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003298611A Abandoned AU2003298611A1 (en) | 2002-11-21 | 2003-11-12 | Mixed lineage kinase modulators |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1567528A1 (en) |
| JP (1) | JP2006522735A (en) |
| AU (1) | AU2003298611A1 (en) |
| CA (1) | CA2506799A1 (en) |
| WO (1) | WO2004048383A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA80571C2 (en) | 2002-11-22 | 2007-10-10 | Lilly Co Eli | Quinolinyl-pyrrolopyrazoles |
| CR9465A (en) * | 2005-03-25 | 2008-06-19 | Surface Logix Inc | PHARMACOCINETICALLY IMPROVED COMPOUNDS |
| SI1910370T1 (en) | 2005-07-22 | 2015-06-30 | Eli Lilly And Company | A pyridin quinolin substituted pyrrolo (1,2-b) pyrazole monohydrate as tgf-beta inhibitor |
| US7919519B2 (en) | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
| EP1965807A4 (en) * | 2005-11-23 | 2010-10-27 | Epix Delaware Inc | S1p receptor modulating compounds and use thereof |
| AR060050A1 (en) | 2006-03-21 | 2008-05-21 | Epix Delaware Inc | MODULATING COMPOUNDS OF THE S1P RECEIVER AND USE OF THE SAME |
| NZ623002A (en) | 2006-06-26 | 2015-08-28 | Akebia Therapeutics Inc | Prolyl hydroxylase inhibitors and methods of use |
| JP5191497B2 (en) * | 2007-03-21 | 2013-05-08 | エピックス ファーマシューティカルズ,インコーポレイテッド | S1P receptor modulating compounds and uses thereof |
| JP2010540438A (en) | 2007-09-20 | 2010-12-24 | アムジエン・インコーポレーテツド | 1- (4-Benzylbenzamido) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as S1P receptor modulators for treating immune disorders |
| DE102009001438A1 (en) | 2009-03-10 | 2010-09-16 | Bayer Schering Pharma Aktiengesellschaft | New carbonylamino-substituted anilino-pyrimidine compounds are tyrosine kinase-2 inhibitors, useful for treating diseases associated with inflammatory conditions e.g. bronchitis, rheumatoid arthritis, psoriasis and Guillain Barre syndrome |
| DE102009015070A1 (en) | 2009-03-30 | 2010-10-14 | Bayer Schering Pharma Aktiengesellschaft | New phenyl-pyrimidin-2-yl-amine compounds are tyrosine kinase 2 inhibitors useful for treating e.g. rheumatoid arthritis, Crohn's disease, asthma, multiple sclerosis, adult respiratory distress syndrome, allergic alveolitis and uveitis |
| US20120329836A1 (en) | 2011-06-06 | 2012-12-27 | The Ohio State University | Methods for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
| NO2686520T3 (en) | 2011-06-06 | 2018-03-17 | ||
| SI3007695T1 (en) | 2013-06-13 | 2024-04-30 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| JP2018502882A (en) | 2015-01-23 | 2018-02-01 | アケビア セラピューティクス インコーポレイテッドAkebia Therapeutics Inc. | Solid form of 2- (5- (3-fluorophenyl) -3-hydroxypicolinamide) acetic acid, its composition and use |
| EP3277673B1 (en) | 2015-04-01 | 2022-05-04 | Rigel Pharmaceuticals, Inc. | Tgf-beta inhibitors |
| HRP20211862T1 (en) | 2015-04-01 | 2022-03-04 | Akebia Therapeutics, Inc. | PREPARATIONS FOR AND PROCEDURES FOR THE TREATMENT OF ANEMIA |
| CN107663206B (en) | 2016-07-29 | 2021-06-18 | 上海璎黎药业有限公司 | Nitrogen-containing aromatic heterocyclic compound, its preparation method, pharmaceutical composition and application |
| CN110066277B (en) | 2018-01-24 | 2021-07-23 | 上海璎黎药业有限公司 | Aromatic heterocyclic substituted olefin compound, preparation method, pharmaceutical composition and application thereof |
| CN110066276B (en) | 2018-01-24 | 2020-09-18 | 上海璎黎药业有限公司 | Aromatic heterocyclic compound, intermediate thereof, preparation method, pharmaceutical composition and application |
| TWI822776B (en) | 2018-05-09 | 2023-11-21 | 美商阿克比治療有限公司 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| CN114437082B (en) * | 2020-11-06 | 2025-04-04 | 江苏先声药业有限公司 | Quinoline compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356897A (en) * | 1991-09-09 | 1994-10-18 | Fujisawa Pharmaceutical Co., Ltd. | 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines |
| CZ303808B6 (en) * | 2001-05-24 | 2013-05-09 | Eli Lilly And Company | Novel pyrrole derivatives as pharmaceutical agents |
-
2003
- 2003-11-12 CA CA002506799A patent/CA2506799A1/en not_active Abandoned
- 2003-11-12 JP JP2004555371A patent/JP2006522735A/en not_active Withdrawn
- 2003-11-12 EP EP03796362A patent/EP1567528A1/en not_active Withdrawn
- 2003-11-12 WO PCT/US2003/035036 patent/WO2004048383A1/en not_active Ceased
- 2003-11-12 AU AU2003298611A patent/AU2003298611A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004048383A1 (en) | 2004-06-10 |
| CA2506799A1 (en) | 2004-06-10 |
| JP2006522735A (en) | 2006-10-05 |
| EP1567528A1 (en) | 2005-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |