AU2003289546A1 - Process for preparing simvastatin. - Google Patents
Process for preparing simvastatin.Info
- Publication number
- AU2003289546A1 AU2003289546A1 AU2003289546A AU2003289546A AU2003289546A1 AU 2003289546 A1 AU2003289546 A1 AU 2003289546A1 AU 2003289546 A AU2003289546 A AU 2003289546A AU 2003289546 A AU2003289546 A AU 2003289546A AU 2003289546 A1 AU2003289546 A1 AU 2003289546A1
- Authority
- AU
- Australia
- Prior art keywords
- preparing simvastatin
- simvastatin
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- RYMZZMVNJRMUDD-UHFFFAOYSA-N SJ000286063 Natural products C12C(OC(=O)C(C)(C)CC)CC(C)C=C2C=CC(C)C1CCC1CC(O)CC(=O)O1 RYMZZMVNJRMUDD-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- RYMZZMVNJRMUDD-HGQWONQESA-N simvastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 RYMZZMVNJRMUDD-HGQWONQESA-N 0.000 title 1
- 229960002855 simvastatin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/KR2003/002754 WO2005058861A1 (en) | 2003-12-16 | 2003-12-16 | Process for preparing simvastatin. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003289546A1 true AU2003289546A1 (en) | 2005-07-05 |
Family
ID=34698338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003289546A Abandoned AU2003289546A1 (en) | 2003-12-16 | 2003-12-16 | Process for preparing simvastatin. |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003289546A1 (en) |
| WO (1) | WO2005058861A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009013764A2 (en) * | 2007-07-24 | 2009-01-29 | Jubilant Organosys Limited | Process for producing 6(r)-[2-(8'(s)-2 ',2 '-dimethylbutyryloxy-2'(s),6'(r)-dimethyl-1,2,6,7', 8',8a'(r)- hexahydronaphthyl-l'(s))ethyl]-4(r)-hydroxy-3,4,5,6- tetrahydro-2h-pyran-2-one |
| HK1214752A1 (en) | 2013-03-15 | 2016-08-05 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US9289418B2 (en) | 2013-03-15 | 2016-03-22 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| BR112017002761A2 (en) | 2014-08-13 | 2017-12-19 | Cedars Sinai Medical Center | anti-methanogenic compositions and uses thereof |
| WO2016161085A1 (en) | 2015-04-01 | 2016-10-06 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444784A (en) * | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| EP0940395A1 (en) * | 1998-03-05 | 1999-09-08 | Synthon B.V. | Process for producing simvastatin and/or its derivatives |
| CA2240983A1 (en) * | 1998-06-18 | 1999-12-18 | Yong Tao | Process to manufacture simvastatin and intermediates |
| AU1683000A (en) * | 1998-12-10 | 2000-06-26 | Kaneka Corporation | Process for producing simvastatin |
| SI20159A (en) * | 1999-02-04 | 2000-08-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | New process for the removal of the silyloxy protective group from 4-silyoxy tetrahydro-pyran-2-ons |
| KR100435142B1 (en) * | 2002-01-09 | 2004-06-09 | 한미약품 주식회사 | Improved process for the preparation of simvastatin |
-
2003
- 2003-12-16 AU AU2003289546A patent/AU2003289546A1/en not_active Abandoned
- 2003-12-16 WO PCT/KR2003/002754 patent/WO2005058861A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005058861A1 (en) | 2005-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |