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AU2003283947A1 - Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids - Google Patents

Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Info

Publication number
AU2003283947A1
AU2003283947A1 AU2003283947A AU2003283947A AU2003283947A1 AU 2003283947 A1 AU2003283947 A1 AU 2003283947A1 AU 2003283947 A AU2003283947 A AU 2003283947A AU 2003283947 A AU2003283947 A AU 2003283947A AU 2003283947 A1 AU2003283947 A1 AU 2003283947A1
Authority
AU
Australia
Prior art keywords
mutants
deletion
amino acids
terminal amino
necrosis factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003283947A
Other versions
AU2003283947A8 (en
Inventor
Irena Fonda
Vladka Gaberc-Porekar
Maja Kenig
Viktor Menart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lek Pharmaceuticals dd
Original Assignee
Lek Pharmaceuticals dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals dd filed Critical Lek Pharmaceuticals dd
Publication of AU2003283947A8 publication Critical patent/AU2003283947A8/en
Publication of AU2003283947A1 publication Critical patent/AU2003283947A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003283947A 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids Abandoned AU2003283947A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SIP-200200279 2002-11-22
SI200200279A SI21373A (en) 2002-11-22 2002-11-22 Method of modulating biological activity of proteins
PCT/SI2003/000041 WO2004048409A2 (en) 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Publications (2)

Publication Number Publication Date
AU2003283947A8 AU2003283947A8 (en) 2004-06-18
AU2003283947A1 true AU2003283947A1 (en) 2004-06-18

Family

ID=32391126

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003283947A Abandoned AU2003283947A1 (en) 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Country Status (3)

Country Link
AU (1) AU2003283947A1 (en)
SI (1) SI21373A (en)
WO (1) WO2004048409A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7318925B2 (en) 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
US7288253B2 (en) 2003-08-08 2007-10-30 Amgen Fremont, Inc. Antibodies directed to parathyroid hormone (PTH) and uses thereof
EP1598075A1 (en) * 2004-05-21 2005-11-23 LEK Pharmaceuticals d.d. Process for the isolation and / or purification of proteins
TWI667253B (en) * 2016-12-30 2019-08-01 博晟生醫股份有限公司 Recombinant polypeptides and nucleic acid molecules, compositions, and methods of making and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677063A (en) * 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
ATE234918T1 (en) * 1995-08-04 2003-04-15 Lek Tovarna Farmacevtskih MONOCLONAL ANTIBODIES AGAINST SOLUBLE TNF-ALPHA RECEPTORS P55 AND P75 AS WELL AS AGAINST TNF-ALPHA AND ITS ANALOGUES

Also Published As

Publication number Publication date
WO2004048409A3 (en) 2004-09-16
AU2003283947A8 (en) 2004-06-18
WO2004048409A2 (en) 2004-06-10
SI21373A (en) 2004-06-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase