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AU2003269871A1 - Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients - Google Patents

Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients

Info

Publication number
AU2003269871A1
AU2003269871A1 AU2003269871A AU2003269871A AU2003269871A1 AU 2003269871 A1 AU2003269871 A1 AU 2003269871A1 AU 2003269871 A AU2003269871 A AU 2003269871A AU 2003269871 A AU2003269871 A AU 2003269871A AU 2003269871 A1 AU2003269871 A1 AU 2003269871A1
Authority
AU
Australia
Prior art keywords
analogs
acetylphytosphingosine
phytosphingosine
dimethyl
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003269871A
Inventor
Young-Soo Han
Jie-Young Song
Yeon-Sook Yun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Atomic Energy Research Institute KAERI
Original Assignee
Korea Atomic Energy Research Institute KAERI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Atomic Energy Research Institute KAERI filed Critical Korea Atomic Energy Research Institute KAERI
Publication of AU2003269871A1 publication Critical patent/AU2003269871A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D331/00Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/02Three-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2003269871A 2002-05-20 2003-03-03 Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients Abandoned AU2003269871A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2002-0027739A KR100459484B1 (en) 2002-05-20 2002-05-20 Radiosensitizer composition containing N-acetylphytosphingosine and dimethylphytosphingosine as the active ingredients
KR10-2002-0027739 2002-05-20
PCT/KR2003/000406 WO2003097631A1 (en) 2002-05-20 2003-03-03 Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients

Publications (1)

Publication Number Publication Date
AU2003269871A1 true AU2003269871A1 (en) 2003-12-02

Family

ID=27726406

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003269871A Abandoned AU2003269871A1 (en) 2002-05-20 2003-03-03 Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients

Country Status (3)

Country Link
KR (1) KR100459484B1 (en)
AU (1) AU2003269871A1 (en)
WO (1) WO2003097631A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100532579B1 (en) * 2002-08-14 2005-12-19 주식회사 바이오씨에스 A pharmaceutical composition comprising phytospingosine derivatives for preventing and treating keratosis or skin cancer
US20060166934A1 (en) * 2002-08-14 2006-07-27 Tae-Yoon Kim Composition comprising phytosphingosine derivatives for apoptosis induction
KR100736145B1 (en) * 2004-06-01 2007-07-06 주식회사 두산 Monomethylpytosphingosine-polyethylene glycol and anticancer composition containing same
KR100823146B1 (en) * 2006-12-28 2008-04-22 재단법인 한국원자력의학원 Novel Phytosphingosine Derivatives and Radiotherapy Enhancers Using the Same
KR101342851B1 (en) 2011-12-07 2013-12-17 가톨릭대학교 산학협력단 Novel phytosphingosine derivatives and composition for preventing and treating inflammatory skin diseases, autoimmune diseases and hyperkeratotic disorders
KR102299509B1 (en) * 2015-03-31 2021-09-07 (주)아모레퍼시픽 Phytosphingosine Derivatives and Composition Comprising Thereof
WO2022158993A1 (en) * 2021-01-25 2022-07-28 Carbocode S.A. Method for the production of d-erythro-sphingosine and analogs thereof
KR102704414B1 (en) 2021-10-12 2024-09-09 한국원자력의학원 Composition for Enhancing Efficacy of Radiotherapy of Cancer Comprising Butyrate as Active Ingredient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583160A (en) * 1989-02-03 1996-12-10 The Biomembrane Institute Methylsphingosine used to treat apoptosis
CA2007507C (en) * 1989-02-03 1998-05-19 Yasuyuki Igarashi Sphingosine and n-methyl-sphingosine as inhibitor of cell growth
DE4025316A1 (en) * 1990-08-09 1992-02-13 Basf Ag New 3,4-epoxy:sphingosine derivs. - for use in tumour and immune therapy and to influence circulation, also as intermediates for ceramide(s) and glycosphingolipid(s)
JPH11269190A (en) * 1998-03-19 1999-10-05 Nissin Food Prod Co Ltd Compound having immunomodulative activity
US7820718B1 (en) * 1999-04-07 2010-10-26 Roger Williams Hospital Combinations of ceramide and chemotherapeutic agents for inducing cell death and uses thereof in treating cancer
KR100371491B1 (en) * 1999-07-27 2003-02-07 주식회사 두산 Cream Composition For Skin Care
KR100457113B1 (en) * 2001-12-27 2004-11-16 한국원자력연구소 Radiosensitizer containing ceramides or derivatives thereof and dimethylsphingosine as the active ingredient

Also Published As

Publication number Publication date
KR20020042606A (en) 2002-06-05
KR100459484B1 (en) 2004-12-03
WO2003097631A1 (en) 2003-11-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase