AU2003269871A1 - Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients - Google Patents
Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredientsInfo
- Publication number
- AU2003269871A1 AU2003269871A1 AU2003269871A AU2003269871A AU2003269871A1 AU 2003269871 A1 AU2003269871 A1 AU 2003269871A1 AU 2003269871 A AU2003269871 A AU 2003269871A AU 2003269871 A AU2003269871 A AU 2003269871A AU 2003269871 A1 AU2003269871 A1 AU 2003269871A1
- Authority
- AU
- Australia
- Prior art keywords
- analogs
- acetylphytosphingosine
- phytosphingosine
- dimethyl
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000004480 active ingredient Substances 0.000 title 1
- SZUJJDLBXJCDNT-ZCNNSNEGSA-N n-[(2s,3s,4r)-1,3,4-trihydroxyoctadecan-2-yl]acetamide Chemical class CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(C)=O SZUJJDLBXJCDNT-ZCNNSNEGSA-N 0.000 title 1
- 239000002534 radiation-sensitizing agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
- C07D331/02—Three-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2002-0027739A KR100459484B1 (en) | 2002-05-20 | 2002-05-20 | Radiosensitizer composition containing N-acetylphytosphingosine and dimethylphytosphingosine as the active ingredients |
| KR10-2002-0027739 | 2002-05-20 | ||
| PCT/KR2003/000406 WO2003097631A1 (en) | 2002-05-20 | 2003-03-03 | Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003269871A1 true AU2003269871A1 (en) | 2003-12-02 |
Family
ID=27726406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003269871A Abandoned AU2003269871A1 (en) | 2002-05-20 | 2003-03-03 | Radiosensitizer composition containing n-acetylphytosphingosine analogs and n,n-dimethyl-phytosphingosine analogs as the active ingredients |
Country Status (3)
| Country | Link |
|---|---|
| KR (1) | KR100459484B1 (en) |
| AU (1) | AU2003269871A1 (en) |
| WO (1) | WO2003097631A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100532579B1 (en) * | 2002-08-14 | 2005-12-19 | 주식회사 바이오씨에스 | A pharmaceutical composition comprising phytospingosine derivatives for preventing and treating keratosis or skin cancer |
| US20060166934A1 (en) * | 2002-08-14 | 2006-07-27 | Tae-Yoon Kim | Composition comprising phytosphingosine derivatives for apoptosis induction |
| KR100736145B1 (en) * | 2004-06-01 | 2007-07-06 | 주식회사 두산 | Monomethylpytosphingosine-polyethylene glycol and anticancer composition containing same |
| KR100823146B1 (en) * | 2006-12-28 | 2008-04-22 | 재단법인 한국원자력의학원 | Novel Phytosphingosine Derivatives and Radiotherapy Enhancers Using the Same |
| KR101342851B1 (en) | 2011-12-07 | 2013-12-17 | 가톨릭대학교 산학협력단 | Novel phytosphingosine derivatives and composition for preventing and treating inflammatory skin diseases, autoimmune diseases and hyperkeratotic disorders |
| KR102299509B1 (en) * | 2015-03-31 | 2021-09-07 | (주)아모레퍼시픽 | Phytosphingosine Derivatives and Composition Comprising Thereof |
| WO2022158993A1 (en) * | 2021-01-25 | 2022-07-28 | Carbocode S.A. | Method for the production of d-erythro-sphingosine and analogs thereof |
| KR102704414B1 (en) | 2021-10-12 | 2024-09-09 | 한국원자력의학원 | Composition for Enhancing Efficacy of Radiotherapy of Cancer Comprising Butyrate as Active Ingredient |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583160A (en) * | 1989-02-03 | 1996-12-10 | The Biomembrane Institute | Methylsphingosine used to treat apoptosis |
| CA2007507C (en) * | 1989-02-03 | 1998-05-19 | Yasuyuki Igarashi | Sphingosine and n-methyl-sphingosine as inhibitor of cell growth |
| DE4025316A1 (en) * | 1990-08-09 | 1992-02-13 | Basf Ag | New 3,4-epoxy:sphingosine derivs. - for use in tumour and immune therapy and to influence circulation, also as intermediates for ceramide(s) and glycosphingolipid(s) |
| JPH11269190A (en) * | 1998-03-19 | 1999-10-05 | Nissin Food Prod Co Ltd | Compound having immunomodulative activity |
| US7820718B1 (en) * | 1999-04-07 | 2010-10-26 | Roger Williams Hospital | Combinations of ceramide and chemotherapeutic agents for inducing cell death and uses thereof in treating cancer |
| KR100371491B1 (en) * | 1999-07-27 | 2003-02-07 | 주식회사 두산 | Cream Composition For Skin Care |
| KR100457113B1 (en) * | 2001-12-27 | 2004-11-16 | 한국원자력연구소 | Radiosensitizer containing ceramides or derivatives thereof and dimethylsphingosine as the active ingredient |
-
2002
- 2002-05-20 KR KR10-2002-0027739A patent/KR100459484B1/en not_active Expired - Lifetime
-
2003
- 2003-03-03 AU AU2003269871A patent/AU2003269871A1/en not_active Abandoned
- 2003-03-03 WO PCT/KR2003/000406 patent/WO2003097631A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020042606A (en) | 2002-06-05 |
| KR100459484B1 (en) | 2004-12-03 |
| WO2003097631A1 (en) | 2003-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |