AU2003269486A1 - An improved process for the preparation of pure nisoldipine - Google Patents
An improved process for the preparation of pure nisoldipineInfo
- Publication number
- AU2003269486A1 AU2003269486A1 AU2003269486A AU2003269486A AU2003269486A1 AU 2003269486 A1 AU2003269486 A1 AU 2003269486A1 AU 2003269486 A AU2003269486 A AU 2003269486A AU 2003269486 A AU2003269486 A AU 2003269486A AU 2003269486 A1 AU2003269486 A1 AU 2003269486A1
- Authority
- AU
- Australia
- Prior art keywords
- nisoldipine
- pure
- preparation
- improved process
- improved
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- VKQFCGNPDRICFG-UHFFFAOYSA-N methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1C1=CC=CC=C1[N+]([O-])=O VKQFCGNPDRICFG-UHFFFAOYSA-N 0.000 title 1
- 229960000227 nisoldipine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2003/000309 WO2005023768A1 (en) | 2003-09-11 | 2003-09-11 | An improved process for the preparation of pure nisoldipine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003269486A1 true AU2003269486A1 (en) | 2005-03-29 |
Family
ID=34259924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003269486A Abandoned AU2003269486A1 (en) | 2003-09-11 | 2003-09-11 | An improved process for the preparation of pure nisoldipine |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003269486A1 (en) |
| WO (1) | WO2005023768A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102491940B (en) * | 2011-11-28 | 2013-03-06 | 海南美兰史克制药有限公司 | Nisoldipine compound and novel preparation method thereof |
| CN102976949B (en) * | 2012-12-07 | 2015-01-07 | 青岛黄海制药有限责任公司 | Preparation method of methyl 2-nitrobenzal acetoacetate |
| CN116425635A (en) * | 2020-03-24 | 2023-07-14 | 合肥立方制药股份有限公司 | A kind of method using combination catalyst to synthesize nifedipine intermediate |
| CN118771988A (en) * | 2024-06-12 | 2024-10-15 | 陕西西岳制药(扶风)有限公司 | A method for synthesizing nifedipine intermediate 2-(3-nitrobenzylidene)-methyl acetoacetate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4600778A (en) * | 1983-04-05 | 1986-07-15 | Bayer Aktiengesellschaft | Process for the preparation of 1,4-dihydropyridinedicarboxylic esters |
| ATE234286T1 (en) * | 1993-12-10 | 2003-03-15 | Bayer Ag | PHENYL-SUBSTITUTED 1,4-DIHYDROPYRIDINES WITH CEREBRAL ACTIVITY |
| JPH1175189A (en) * | 1997-08-27 | 1999-03-16 | Mitsubishi Electric Corp | Image coding method |
-
2003
- 2003-09-11 WO PCT/IN2003/000309 patent/WO2005023768A1/en not_active Ceased
- 2003-09-11 AU AU2003269486A patent/AU2003269486A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005023768A1 (en) | 2005-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |