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AU2003260291A1 - Proximity-aided synthesis of templated molecules - Google Patents

Proximity-aided synthesis of templated molecules

Info

Publication number
AU2003260291A1
AU2003260291A1 AU2003260291A AU2003260291A AU2003260291A1 AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1 AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1
Authority
AU
Australia
Prior art keywords
proximity
templated molecules
aided synthesis
aided
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003260291A
Other versions
AU2003260291A8 (en
Inventor
Thomas Franch
Thomas Thisted
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuevolution AS
Original Assignee
Nuevolution AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution AS filed Critical Nuevolution AS
Publication of AU2003260291A1 publication Critical patent/AU2003260291A1/en
Publication of AU2003260291A8 publication Critical patent/AU2003260291A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Wind Motors (AREA)
AU2003260291A 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules Abandoned AU2003260291A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40996802P 2002-09-12 2002-09-12
DKPA200201347 2002-09-12
DKPA200201347 2002-09-12
US60/409,968 2002-09-12
PCT/DK2003/000590 WO2004024929A2 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Publications (2)

Publication Number Publication Date
AU2003260291A1 true AU2003260291A1 (en) 2004-04-30
AU2003260291A8 AU2003260291A8 (en) 2004-04-30

Family

ID=31995414

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003260291A Abandoned AU2003260291A1 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Country Status (3)

Country Link
EP (1) EP1539953A2 (en)
AU (1) AU2003260291A1 (en)
WO (1) WO2004024929A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2332896A3 (en) 2001-03-19 2012-09-26 President and Fellows of Harvard College Evolving new molecular function
WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
DE60324778D1 (en) 2002-03-15 2009-01-02 Nuevolution As AN IMPROVED METHOD FOR SYNTHESIS OF MATTRESS-RELATED MOLECULES
EP1539980B1 (en) 2002-08-01 2016-02-17 Nuevolution A/S Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules
CA2495881C (en) 2002-08-19 2014-07-08 The President And Fellows Of Harvard College Evolving new molecular function
CN1720331B (en) * 2002-10-30 2013-01-02 纽韦卢森公司 Method for synthesizing bifunctional complexes
AU2011226815B2 (en) * 2002-10-30 2014-09-25 Nuevolution A/S Enzymatic encoding
AU2003291964A1 (en) 2002-12-19 2004-07-14 Nuevolution A/S Quasirandom structure and function guided synthesis methods
EP1597395A2 (en) 2003-02-21 2005-11-23 Nuevolution A/S Method for producing second-generation library
DE602004019764D1 (en) 2003-03-20 2009-04-16 Nuevolution As LIGATION-RELATED CODING OF SMALL MOLECULES
DK1670939T3 (en) * 2003-09-18 2010-03-01 Nuevolution As Method for obtaining structural information on a coded molecule and method for selecting compounds
BRPI0417830B1 (en) 2003-12-17 2021-02-17 Praecis Pharmaceuticals Inc methods for synthesizing a molecule comprising a functional portion operably linked to a coding oligonucleotide
US7972994B2 (en) 2003-12-17 2011-07-05 Glaxosmithkline Llc Methods for synthesis of encoded libraries
US7704925B2 (en) 2004-03-22 2010-04-27 Nuevolution A/S Ligational encoding using building block oligonucleotides
ATE419344T1 (en) * 2004-11-08 2009-01-15 Vipergen Aps STRUCTURAL NUCLEIC ACID-GUIDED CHEMICAL SYNTHESIS
US8183178B2 (en) 2005-06-17 2012-05-22 President And Fellows Of Harvard College Iterated branching reaction pathways via nucleic acid-mediated chemistry
EP2368868A1 (en) 2005-10-28 2011-09-28 Praecis Pharmaceuticals Inc. Methods for identifying compounds of interest using encoded libraries
DK3018206T3 (en) 2005-12-01 2021-11-15 Nuevolution As ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
DK3211126T3 (en) 2009-02-13 2020-12-21 X Chem Inc METHODS FOR FORMING AND SCREENING DNA-CODED LIBRARIES
EP2558577B1 (en) 2010-04-16 2018-12-12 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
EP3351631B1 (en) 2011-09-07 2020-11-04 X-Chem, Inc. Methods for tagging dna-encoded libraries
DK3392338T3 (en) 2012-07-13 2021-02-01 X Chem Inc DNA-CODED LIBRARIES WITH CODING OLIGONUCLEOTID BINDS WHICH CANNOT BE READ BY POLYMERASES
EP3532613A4 (en) * 2016-10-26 2020-05-06 ModernaTX, Inc. METHODS AND COMPOSITIONS FOR RNA MAPPING
WO2020051452A2 (en) * 2018-09-07 2020-03-12 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Hiv or hcv detection with crispr-cas13a
EP3938507A4 (en) 2019-03-11 2023-02-22 ModernaTX, Inc. Fed-batch in vitro transcription process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
WO2000023458A1 (en) * 1998-10-19 2000-04-27 The Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library chemistry
EP2332896A3 (en) * 2001-03-19 2012-09-26 President and Fellows of Harvard College Evolving new molecular function
DE60324778D1 (en) * 2002-03-15 2009-01-02 Nuevolution As AN IMPROVED METHOD FOR SYNTHESIS OF MATTRESS-RELATED MOLECULES

Also Published As

Publication number Publication date
EP1539953A2 (en) 2005-06-15
WO2004024929A3 (en) 2004-05-06
AU2003260291A8 (en) 2004-04-30
WO2004024929A2 (en) 2004-03-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase