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AU2003241346A1 - Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer - Google Patents

Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer

Info

Publication number
AU2003241346A1
AU2003241346A1 AU2003241346A AU2003241346A AU2003241346A1 AU 2003241346 A1 AU2003241346 A1 AU 2003241346A1 AU 2003241346 A AU2003241346 A AU 2003241346A AU 2003241346 A AU2003241346 A AU 2003241346A AU 2003241346 A1 AU2003241346 A1 AU 2003241346A1
Authority
AU
Australia
Prior art keywords
pentamidine
methods
same
therapeutic compositions
treat cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003241346A
Other versions
AU2003241346A8 (en
Inventor
Taolin Yi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cleveland Clinic Foundation
Original Assignee
Cleveland Clinic Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/238,007 external-priority patent/US7416723B2/en
Priority claimed from US10/354,357 external-priority patent/US20030161893A1/en
Application filed by Cleveland Clinic Foundation filed Critical Cleveland Clinic Foundation
Publication of AU2003241346A1 publication Critical patent/AU2003241346A1/en
Publication of AU2003241346A8 publication Critical patent/AU2003241346A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • G01N33/575—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003241346A 2002-05-01 2003-05-01 Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer Abandoned AU2003241346A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US37678902P 2002-05-01 2002-05-01
US60/376,789 2002-05-01
US10/238,007 US7416723B2 (en) 2001-09-07 2002-09-09 Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases
US10/238,007 2002-09-09
US10/354,357 US20030161893A1 (en) 2001-09-07 2003-01-30 PTPase inhibitors and methods of using the same
US10/354,357 2003-01-30
US46073503P 2003-04-04 2003-04-04
US60/460,735 2003-04-04
PCT/US2003/013744 WO2003092616A2 (en) 2002-05-01 2003-05-01 Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer

Publications (2)

Publication Number Publication Date
AU2003241346A1 true AU2003241346A1 (en) 2003-11-17
AU2003241346A8 AU2003241346A8 (en) 2003-11-17

Family

ID=29408046

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003241346A Abandoned AU2003241346A1 (en) 2002-05-01 2003-05-01 Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer

Country Status (2)

Country Link
AU (1) AU2003241346A1 (en)
WO (1) WO2003092616A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5693850B2 (en) 2007-02-06 2015-04-01 リクスト・バイオテクノロジー，インコーポレイテッド Oxabicycloheptane and oxabicycloheptene, their production and use
WO2010147612A1 (en) 2009-06-18 2010-12-23 Lixte Biotechnology, Inc. Methods of modulating cell regulation by inhibiting p53
US8058268B2 (en) 2008-08-01 2011-11-15 Lixte Biotechnology, Inc. Neuroprotective agents for the prevention and treatment of neurodegenerative diseases
US8227473B2 (en) 2008-08-01 2012-07-24 Lixte Biotechnology, Inc. Oxabicycloheptanes and oxabicycloheptenes, their preparation and use
CA2758856A1 (en) * 2009-05-01 2010-11-04 Oncozyme Pharma Inc. Pentamidine combinations for treating cancer
EP2934501A4 (en) * 2012-12-21 2016-06-01 Verlyx Pharma Inc Uses and methods for the treatment of liver diseases or conditions
CN105209036B (en) 2013-04-09 2018-10-26 莱克斯特生物技术公司 The preparation of oxa-bicyclo heptane and oxabicyclo heptene
CA3046515A1 (en) 2016-12-08 2018-06-14 Lixte Biotechnology, Inc. Oxabicycloheptanes for modulation of immune response
WO2023144830A1 (en) 2022-01-30 2023-08-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Zika m protein blockers as anti-zika virus agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988007855A1 (en) * 1987-04-09 1988-10-20 Fisons Plc Pharmaceutical compositions containing pentamidine
US6020179A (en) * 1996-10-03 2000-02-01 Incyte Pharmaceuticals, Inc. Nucleic acids encoding human tyrosine phosphatases
US6258582B1 (en) * 1998-09-30 2001-07-10 Millennium Pharmaceuticals, Inc. CSAPTP nucleic acid molecules and uses therefor
US6569853B1 (en) * 2000-11-06 2003-05-27 Combinatorx, Incorporated Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
US6693125B2 (en) * 2001-01-24 2004-02-17 Combinatorx Incorporated Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders

Also Published As

Publication number Publication date
WO2003092616A2 (en) 2003-11-13
AU2003241346A8 (en) 2003-11-17
WO2003092616A3 (en) 2004-07-01

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase