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AU2002788A - Specific excretion-secretion antigens of toxoplasma gondii, their expression products, processes for obtaining them and their diagnostic and prophylactic uses - Google Patents

Specific excretion-secretion antigens of toxoplasma gondii, their expression products, processes for obtaining them and their diagnostic and prophylactic uses

Info

Publication number
AU2002788A
AU2002788A AU20027/88A AU2002788A AU2002788A AU 2002788 A AU2002788 A AU 2002788A AU 20027/88 A AU20027/88 A AU 20027/88A AU 2002788 A AU2002788 A AU 2002788A AU 2002788 A AU2002788 A AU 2002788A
Authority
AU
Australia
Prior art keywords
antigens
toxoplasma gondii
diagnostic
obtaining
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU20027/88A
Other versions
AU625171B2 (en
Inventor
Andre Capron
Marie-France Cesbron
Francoise Darcy
Raymond Pierce
Pierre-Richard Ridel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM, Institut Pasteur filed Critical Institut Pasteur de Lille
Publication of AU2002788A publication Critical patent/AU2002788A/en
Application granted granted Critical
Publication of AU625171B2 publication Critical patent/AU625171B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/45—Toxoplasma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Toxoplasma gondii (TG) antigens consisting of excretion-secretion (ES) antigens common to the tachyzoites and the bradyzoites of TG, and translation products of mRNA of tachyzoites carrying the epitopes recognised by the abovementioned ES antigens. Polyclonal and monoclonal antibodies capable of conferring significant protection against toxoplasmosis, in the form of vaccines in particular. Therapeutic composition for the treatment of toxoplasmosis, the active constituents of which are the abovementioned ES antigens. Products for the diagnosis of toxoplasmosis, the active constituents of which are the abovementioned ES antigens.
AU20027/88A 1987-07-31 1988-07-26 Specific excretion-secretion antigens of toxoplasma gondii, their expression products, processes for obtaining them and their diagnostic and prophylactic uses Ceased AU625171B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8710891 1987-07-31
FR8710891A FR2618680B1 (en) 1987-07-31 1987-07-31 TOXOPLASMA GONDII SPECIFIC EXCRETION-SECRETION ANTIGENS, THEIR EXPRESSION PRODUCTS, THE PROCESS FOR OBTAINING SAME AND THEIR DIAGNOSTIC AND PROPHYLACTIC APPLICATIONS

Publications (2)

Publication Number Publication Date
AU2002788A true AU2002788A (en) 1989-02-02
AU625171B2 AU625171B2 (en) 1992-07-02

Family

ID=9353771

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20027/88A Ceased AU625171B2 (en) 1987-07-31 1988-07-26 Specific excretion-secretion antigens of toxoplasma gondii, their expression products, processes for obtaining them and their diagnostic and prophylactic uses

Country Status (10)

Country Link
EP (1) EP0301961B1 (en)
JP (1) JPH01131125A (en)
KR (1) KR890001588A (en)
AT (1) ATE96675T1 (en)
AU (1) AU625171B2 (en)
DE (1) DE3885365T2 (en)
DK (1) DK171259B1 (en)
ES (1) ES2061705T3 (en)
FR (1) FR2618680B1 (en)
PT (1) PT88157B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002624A1 (en) * 1990-08-10 1992-02-20 The Flinders University Of South Australia Cloning and expression of toxoplasma antigens and use of recombinant antigens
AU628052B2 (en) * 1988-05-13 1992-09-10 Sumitomo Pharmaceuticals Company, Limited Proteins having anti-tumour activity
US5859196A (en) * 1988-03-09 1999-01-12 Trustees Of The Leland Stanford Junior University P30 peptides of Toxoplasma gondii

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940598A1 (en) * 1989-12-08 1991-06-13 Behringwerke Ag TOXOPLASMA GONDII-ANTIGENE, THEIR PRODUCTION AND USE
JPH02261382A (en) * 1989-04-03 1990-10-24 Mochida Pharmaceut Co Ltd Novel dna sequence originated from toxoplasma and protein coded therewith
US5215917A (en) * 1989-11-03 1993-06-01 Research Institute Of Palo Alto Medical Foundation Nucleotide sequence encoding the Toxoplasma gondii P22 gene
GB9027728D0 (en) * 1990-12-20 1991-02-13 Smithkline Beecham Biolog Novel protein
ZA958366B (en) * 1994-10-06 1996-04-24 Akzo Nobel Nv New toxoplasma gondii antigens
FR2842813B1 (en) 2002-07-26 2007-06-01 Bio Veto Tests Bvt ANTI-ANTIGENIC ISOTYPE ANTIBODIES FOR EXCRETION SECRETION OF PROMASTIGOTES OR AMASTIGOTS OF Leishmania sp
PT1856159E (en) 2005-03-08 2010-06-22 Sigma Tau Ind Farmaceuti Chimeric recombinant antigens of toxoplasma gondii
KR100818779B1 (en) * 2007-05-22 2008-04-02 에이취디알 주식회사 Trichomonas vaginalis diagnostic kit
MY197339A (en) * 2010-07-07 2023-06-13 Univ Sains Malaysia Uses of biological compounds from toxoplasma sp and related compounds
CN115287257B (en) * 2022-09-29 2022-12-13 广东医科大学附属医院 An osteogenic induced differentiation culture medium based on toxoplasma exocrine protein preparation method and osteogenic induced differentiation method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2518407A1 (en) * 1981-12-17 1983-06-24 Merieux Inst NOVEL ANTIGEN FOR THE RESEARCH OF TOXOPLASMIC IMMUNITY AND ITS PREPARATION METHOD
FR2564731B1 (en) * 1984-05-28 1986-10-10 Ambroise Thomas Pierre NOVEL TOXOPLASMIC EXO-ANTIGENIC FRACTIONS, THEIR PREPARATION PROCESS AND THEIR APPLICATION TO THE RESEARCH OF TOXOPLASMIC IMMUNITY IN MAN BY SKIN TESTS
JP2759457B2 (en) * 1988-05-13 1998-05-28 住友製薬株式会社 Antitumor protein

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859196A (en) * 1988-03-09 1999-01-12 Trustees Of The Leland Stanford Junior University P30 peptides of Toxoplasma gondii
AU628052B2 (en) * 1988-05-13 1992-09-10 Sumitomo Pharmaceuticals Company, Limited Proteins having anti-tumour activity
WO1992002624A1 (en) * 1990-08-10 1992-02-20 The Flinders University Of South Australia Cloning and expression of toxoplasma antigens and use of recombinant antigens

Also Published As

Publication number Publication date
EP0301961B1 (en) 1993-11-03
DK171259B1 (en) 1996-08-12
FR2618680B1 (en) 1990-05-11
PT88157B (en) 1995-03-01
EP0301961A1 (en) 1989-02-01
ATE96675T1 (en) 1993-11-15
JPH01131125A (en) 1989-05-24
FR2618680A1 (en) 1989-02-03
AU625171B2 (en) 1992-07-02
DE3885365T2 (en) 1994-05-05
ES2061705T3 (en) 1994-12-16
DK424988D0 (en) 1988-07-29
DE3885365D1 (en) 1993-12-09
KR890001588A (en) 1989-03-27
PT88157A (en) 1989-06-30
DK424988A (en) 1989-02-01

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired