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AU2002319296A1 - Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processes - Google Patents

Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processes

Info

Publication number
AU2002319296A1
AU2002319296A1 AU2002319296A AU2002319296A AU2002319296A1 AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1 AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1
Authority
AU
Australia
Prior art keywords
alkoxyphenyl
treatment
diseases associated
regulated processes
substituted imidazotriazinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002319296A
Other versions
AU2002319296B2 (en
Inventor
Tiemo-Joerg Bandel
Wolfgang Barth
Erwin Bischoff
Helmut Haning
Ulrich Niewohner
Afssaneh Rahbar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10135815A external-priority patent/DE10135815A1/en
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of AU2002319296A1 publication Critical patent/AU2002319296A1/en
Application granted granted Critical
Publication of AU2002319296B2 publication Critical patent/AU2002319296B2/en
Assigned to BAYER SCHERING PHARMA AKTIENGESELLSCHAFT reassignment BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Request for Assignment Assignors: BAYER HEALTHCARE AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002319296A 2001-07-23 2002-07-17 Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cGMP regulated processes Ceased AU2002319296B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10135815A DE10135815A1 (en) 2001-07-23 2001-07-23 Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain
DE10135815.6 2001-07-23
PCT/EP2002/007959 WO2003011262A2 (en) 2001-07-23 2002-07-17 Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cgmp regulated processes

Publications (2)

Publication Number Publication Date
AU2002319296A1 true AU2002319296A1 (en) 2003-05-29
AU2002319296B2 AU2002319296B2 (en) 2007-08-30

Family

ID=7692784

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002319296A Ceased AU2002319296B2 (en) 2001-07-23 2002-07-17 Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cGMP regulated processes

Country Status (28)

Country Link
US (3) US6930108B2 (en)
EP (2) EP1733728A3 (en)
JP (1) JP2005504751A (en)
KR (1) KR20040032865A (en)
CN (1) CN1649593A (en)
AT (1) ATE442144T1 (en)
AU (1) AU2002319296B2 (en)
BG (1) BG108533A (en)
BR (1) BR0211359A (en)
CA (1) CA2454414A1 (en)
CO (1) CO5560536A2 (en)
CZ (1) CZ2004128A3 (en)
DE (2) DE10135815A1 (en)
EC (1) ECSP044956A (en)
EE (1) EE200400056A (en)
ES (1) ES2330418T3 (en)
HR (1) HRP20040065A2 (en)
HU (1) HUP0500734A3 (en)
IL (1) IL159840A0 (en)
MA (1) MA26128A1 (en)
MX (1) MXPA04000675A (en)
NO (1) NO20040294L (en)
NZ (1) NZ530703A (en)
PL (1) PL373392A1 (en)
RU (1) RU2321406C9 (en)
SK (1) SK442004A3 (en)
UA (1) UA76997C2 (en)
WO (1) WO2003011262A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10135815A1 (en) * 2001-07-23 2003-02-06 Bayer Ag Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain
JP2006219374A (en) * 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Imidazotriazinone derivatives having PDE7 inhibitory action
DE102004023069A1 (en) 2004-05-11 2005-12-08 Bayer Healthcare Ag New dosage forms of the PDE 5 inhibitor vardenafil
DE102004038328A1 (en) * 2004-08-06 2006-03-16 Bayer Healthcare Ag New uses of 2-phenyl-substituted imidazotriazinone derivatives
NZ561746A (en) 2005-04-19 2011-09-30 Nycomed Gmbh Roflumilast for the treatment of pulmonary hypertension
EP2521721B1 (en) 2009-12-30 2014-10-01 Shanghai Fochon Pharmaceutical Co. Ltd 3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors
AT512084A1 (en) * 2011-10-20 2013-05-15 Univ Wien Tech DIAZABICYCLO AND DIAZASPIRO ALKAN DERIVATIVES AS PHOSPHODIESTERASE-5 INHIBITORS
EP3082428A4 (en) 2013-12-09 2017-08-02 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
RU2753056C2 (en) * 2016-12-16 2021-08-11 Систик Файбросис Фаундейшн Bicyclic heteroaryl derivatives as cftr stimulators
CN113583003A (en) * 2021-08-05 2021-11-02 广东西捷药业有限公司 Vardenafil analogue and synthetic method and application thereof
CN113461694A (en) * 2021-08-05 2021-10-01 广东西捷药业有限公司 Vardenafil analogue and synthetic method and application thereof

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791025A (en) 1971-11-19 1973-05-07 Allen & Hanburys Ltd HETEROCYCLIC COMPOUNDS
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DK109578A (en) 1977-03-25 1978-09-26 Allen & Hanburys Ltd PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS
US4308384A (en) 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
US4479210A (en) * 1982-11-19 1984-10-23 U.S. Philips Corporation Record-disc player
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9114760D0 (en) * 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
GB9301192D0 (en) 1993-06-09 1993-06-09 Trott Francis W Flower shaped mechanised table
US6143746A (en) * 1994-01-21 2000-11-07 Icos Corporation Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
US5602110A (en) * 1994-08-31 1997-02-11 Case Western Reserve University Method and composition for treating cystic fibrosis
US5656629A (en) * 1995-03-10 1997-08-12 Sanofi Winthrop, Inc. 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof
KR100430059B1 (en) * 1995-04-10 2004-09-24 후지사와 야꾸힝 고교 가부시키가이샤 Indole derivatives as cGMP-PDE inhibitors
AU722514B2 (en) * 1995-12-28 2000-08-03 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole derivatives
CA2238283C (en) * 1997-05-30 2002-08-20 Cell Pathways, Inc. Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions
CA2309332C (en) * 1997-11-12 2002-12-03 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
DE19812462A1 (en) * 1998-03-23 1999-09-30 Bayer Ag New phosphodiesterase inhibiting 2-phenyl-imidazotriazinone derivatives useful for treating e.g. cardiovascular, cerebrovascular and/or urogenital diseases
CN100436418C (en) * 1997-12-12 2008-11-26 Osi制药公司 N-benzyl-3-indenylacetamide derivatives for the treatment of tumors
US6087368A (en) * 1998-06-08 2000-07-11 Bristol-Myers Squibb Company Quinazolinone inhibitors of cGMP phosphodiesterase
DE19827640A1 (en) 1998-06-20 1999-12-23 Bayer Ag New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction
IL132406A0 (en) * 1998-10-21 2001-03-19 Pfizer Prod Inc Treatment of bph with cgmp elevators
US6225315B1 (en) * 1998-11-30 2001-05-01 Pfizer Inc Method of treating nitrate-induced tolerance
FR2792634B1 (en) * 1999-04-20 2001-06-01 Synthelabo 2-ALCOXY-CYCLOBUTENE-3,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
IL130968A (en) * 1999-07-15 2002-12-01 Shmuel Simon Pharmaceutical composition comprising sildenafil or its analogs, useful for the treatment of tinnitus and hearing loss
WO2001032170A1 (en) * 1999-09-13 2001-05-10 Swope David M Composition and method for decreasing neurologic symptomatology
DE19943815A1 (en) * 1999-09-14 2001-03-15 Merck Patent Gmbh Use of thienopyrimidines
TWI265925B (en) * 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
CA2323008C (en) 1999-10-11 2005-07-12 Pfizer Inc. Pharmaceutically active compounds
ATE341329T1 (en) * 1999-10-12 2006-10-15 Lilly Icos Llc MEDICINAL PRODUCTS FOR THE TREATMENT OF NEUROPATHIES
IL152925A (en) * 1999-10-21 2010-04-15 Pfizer Pharmaceutical compositions for treatment of neuropathy comprising an inhibitor of cyclic guanosine 3',5'-monophosphate phosphodiesterase 5 and either gabapentin or pregabalin
TWI224966B (en) * 1999-11-02 2004-12-11 Pfizer Pharmaceutical composition (I) useful for treating or preventing pulmonary hypertension in a patient
GB0008694D0 (en) * 2000-04-07 2000-05-31 Novartis Ag Organic compounds
CA2407031A1 (en) * 2000-04-19 2001-10-25 Lilly Icos Llc Use of cyclic gmp-specific phosphodiesterase inhibitors for treatment of parkinson's disease
EP1365806A2 (en) * 2000-04-19 2003-12-03 Johns Hopkins University Use of no acttivators for treatment and prevention of gastrointestinal disorders
CN1446084A (en) * 2000-08-11 2003-10-01 辉瑞大药厂 Treatment of insulin resistance syndrome
JP2004507514A (en) * 2000-08-30 2004-03-11 リリー アイコス リミテッド ライアビリティ カンパニー Migraine treatment
GB0025782D0 (en) * 2000-10-20 2000-12-06 Pfizer Ltd Use of inhibitors
EP1355651A2 (en) * 2001-02-02 2003-10-29 Pfizer Limited Treatment of diabetes mellitus using vardenafil
DE10107639A1 (en) * 2001-02-15 2002-08-22 Bayer Ag 2-alkoxyphenyl substituted imidazotriazinones
WO2002089808A1 (en) * 2001-05-09 2002-11-14 Bayer Healthcare Ag Novel use of 2-phenyl-substituted imidazotriazinones
DE10135815A1 (en) * 2001-07-23 2003-02-06 Bayer Ag Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain
GB0129274D0 (en) * 2001-12-06 2002-01-23 Pfizer Ltd Novel kit
JP2005527510A (en) * 2002-03-06 2005-09-15 セレジー ファーマシューティカルズ インコーポレーティッド Formulations and methods for using nitric oxide mimetics in the treatment of cancer

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