AU2002319296A1 - Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processes - Google Patents
Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processesInfo
- Publication number
- AU2002319296A1 AU2002319296A1 AU2002319296A AU2002319296A AU2002319296A1 AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1 AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1
- Authority
- AU
- Australia
- Prior art keywords
- alkoxyphenyl
- treatment
- diseases associated
- regulated processes
- substituted imidazotriazinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- IJYHVZICHKCLMQ-UHFFFAOYSA-N imidazo[4,5-d]triazin-4-one Chemical class O=C1N=NN=C2N=CN=C12 IJYHVZICHKCLMQ-UHFFFAOYSA-N 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10135815A DE10135815A1 (en) | 2001-07-23 | 2001-07-23 | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
| DE10135815.6 | 2001-07-23 | ||
| PCT/EP2002/007959 WO2003011262A2 (en) | 2001-07-23 | 2002-07-17 | Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cgmp regulated processes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002319296A1 true AU2002319296A1 (en) | 2003-05-29 |
| AU2002319296B2 AU2002319296B2 (en) | 2007-08-30 |
Family
ID=7692784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002319296A Ceased AU2002319296B2 (en) | 2001-07-23 | 2002-07-17 | Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cGMP regulated processes |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US6930108B2 (en) |
| EP (2) | EP1733728A3 (en) |
| JP (1) | JP2005504751A (en) |
| KR (1) | KR20040032865A (en) |
| CN (1) | CN1649593A (en) |
| AT (1) | ATE442144T1 (en) |
| AU (1) | AU2002319296B2 (en) |
| BG (1) | BG108533A (en) |
| BR (1) | BR0211359A (en) |
| CA (1) | CA2454414A1 (en) |
| CO (1) | CO5560536A2 (en) |
| CZ (1) | CZ2004128A3 (en) |
| DE (2) | DE10135815A1 (en) |
| EC (1) | ECSP044956A (en) |
| EE (1) | EE200400056A (en) |
| ES (1) | ES2330418T3 (en) |
| HR (1) | HRP20040065A2 (en) |
| HU (1) | HUP0500734A3 (en) |
| IL (1) | IL159840A0 (en) |
| MA (1) | MA26128A1 (en) |
| MX (1) | MXPA04000675A (en) |
| NO (1) | NO20040294L (en) |
| NZ (1) | NZ530703A (en) |
| PL (1) | PL373392A1 (en) |
| RU (1) | RU2321406C9 (en) |
| SK (1) | SK442004A3 (en) |
| UA (1) | UA76997C2 (en) |
| WO (1) | WO2003011262A2 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10135815A1 (en) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
| JP2006219374A (en) * | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Imidazotriazinone derivatives having PDE7 inhibitory action |
| DE102004023069A1 (en) | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | New dosage forms of the PDE 5 inhibitor vardenafil |
| DE102004038328A1 (en) * | 2004-08-06 | 2006-03-16 | Bayer Healthcare Ag | New uses of 2-phenyl-substituted imidazotriazinone derivatives |
| NZ561746A (en) | 2005-04-19 | 2011-09-30 | Nycomed Gmbh | Roflumilast for the treatment of pulmonary hypertension |
| EP2521721B1 (en) | 2009-12-30 | 2014-10-01 | Shanghai Fochon Pharmaceutical Co. Ltd | 3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors |
| AT512084A1 (en) * | 2011-10-20 | 2013-05-15 | Univ Wien Tech | DIAZABICYCLO AND DIAZASPIRO ALKAN DERIVATIVES AS PHOSPHODIESTERASE-5 INHIBITORS |
| EP3082428A4 (en) | 2013-12-09 | 2017-08-02 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
| RU2753056C2 (en) * | 2016-12-16 | 2021-08-11 | Систик Файбросис Фаундейшн | Bicyclic heteroaryl derivatives as cftr stimulators |
| CN113583003A (en) * | 2021-08-05 | 2021-11-02 | 广东西捷药业有限公司 | Vardenafil analogue and synthetic method and application thereof |
| CN113461694A (en) * | 2021-08-05 | 2021-10-01 | 广东西捷药业有限公司 | Vardenafil analogue and synthetic method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791025A (en) | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | HETEROCYCLIC COMPOUNDS |
| GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| DK109578A (en) | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS |
| US4308384A (en) | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
| US4479210A (en) * | 1982-11-19 | 1984-10-23 | U.S. Philips Corporation | Record-disc player |
| GB9013750D0 (en) * | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
| GB9114760D0 (en) * | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
| PH31245A (en) * | 1991-10-30 | 1998-06-18 | Janssen Pharmaceutica Nv | 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives. |
| GB9301192D0 (en) | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
| US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
| US5602110A (en) * | 1994-08-31 | 1997-02-11 | Case Western Reserve University | Method and composition for treating cystic fibrosis |
| US5656629A (en) * | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
| KR100430059B1 (en) * | 1995-04-10 | 2004-09-24 | 후지사와 야꾸힝 고교 가부시키가이샤 | Indole derivatives as cGMP-PDE inhibitors |
| AU722514B2 (en) * | 1995-12-28 | 2000-08-03 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
| CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
| CA2309332C (en) * | 1997-11-12 | 2002-12-03 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| DE19812462A1 (en) * | 1998-03-23 | 1999-09-30 | Bayer Ag | New phosphodiesterase inhibiting 2-phenyl-imidazotriazinone derivatives useful for treating e.g. cardiovascular, cerebrovascular and/or urogenital diseases |
| CN100436418C (en) * | 1997-12-12 | 2008-11-26 | Osi制药公司 | N-benzyl-3-indenylacetamide derivatives for the treatment of tumors |
| US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
| DE19827640A1 (en) | 1998-06-20 | 1999-12-23 | Bayer Ag | New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction |
| IL132406A0 (en) * | 1998-10-21 | 2001-03-19 | Pfizer Prod Inc | Treatment of bph with cgmp elevators |
| US6225315B1 (en) * | 1998-11-30 | 2001-05-01 | Pfizer Inc | Method of treating nitrate-induced tolerance |
| FR2792634B1 (en) * | 1999-04-20 | 2001-06-01 | Synthelabo | 2-ALCOXY-CYCLOBUTENE-3,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
| IL130968A (en) * | 1999-07-15 | 2002-12-01 | Shmuel Simon | Pharmaceutical composition comprising sildenafil or its analogs, useful for the treatment of tinnitus and hearing loss |
| WO2001032170A1 (en) * | 1999-09-13 | 2001-05-10 | Swope David M | Composition and method for decreasing neurologic symptomatology |
| DE19943815A1 (en) * | 1999-09-14 | 2001-03-15 | Merck Patent Gmbh | Use of thienopyrimidines |
| TWI265925B (en) * | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
| CA2323008C (en) | 1999-10-11 | 2005-07-12 | Pfizer Inc. | Pharmaceutically active compounds |
| ATE341329T1 (en) * | 1999-10-12 | 2006-10-15 | Lilly Icos Llc | MEDICINAL PRODUCTS FOR THE TREATMENT OF NEUROPATHIES |
| IL152925A (en) * | 1999-10-21 | 2010-04-15 | Pfizer | Pharmaceutical compositions for treatment of neuropathy comprising an inhibitor of cyclic guanosine 3',5'-monophosphate phosphodiesterase 5 and either gabapentin or pregabalin |
| TWI224966B (en) * | 1999-11-02 | 2004-12-11 | Pfizer | Pharmaceutical composition (I) useful for treating or preventing pulmonary hypertension in a patient |
| GB0008694D0 (en) * | 2000-04-07 | 2000-05-31 | Novartis Ag | Organic compounds |
| CA2407031A1 (en) * | 2000-04-19 | 2001-10-25 | Lilly Icos Llc | Use of cyclic gmp-specific phosphodiesterase inhibitors for treatment of parkinson's disease |
| EP1365806A2 (en) * | 2000-04-19 | 2003-12-03 | Johns Hopkins University | Use of no acttivators for treatment and prevention of gastrointestinal disorders |
| CN1446084A (en) * | 2000-08-11 | 2003-10-01 | 辉瑞大药厂 | Treatment of insulin resistance syndrome |
| JP2004507514A (en) * | 2000-08-30 | 2004-03-11 | リリー アイコス リミテッド ライアビリティ カンパニー | Migraine treatment |
| GB0025782D0 (en) * | 2000-10-20 | 2000-12-06 | Pfizer Ltd | Use of inhibitors |
| EP1355651A2 (en) * | 2001-02-02 | 2003-10-29 | Pfizer Limited | Treatment of diabetes mellitus using vardenafil |
| DE10107639A1 (en) * | 2001-02-15 | 2002-08-22 | Bayer Ag | 2-alkoxyphenyl substituted imidazotriazinones |
| WO2002089808A1 (en) * | 2001-05-09 | 2002-11-14 | Bayer Healthcare Ag | Novel use of 2-phenyl-substituted imidazotriazinones |
| DE10135815A1 (en) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
| GB0129274D0 (en) * | 2001-12-06 | 2002-01-23 | Pfizer Ltd | Novel kit |
| JP2005527510A (en) * | 2002-03-06 | 2005-09-15 | セレジー ファーマシューティカルズ インコーポレーティッド | Formulations and methods for using nitric oxide mimetics in the treatment of cancer |
-
2001
- 2001-07-23 DE DE10135815A patent/DE10135815A1/en not_active Withdrawn
-
2002
- 2002-07-17 JP JP2003516493A patent/JP2005504751A/en active Pending
- 2002-07-17 ES ES02748858T patent/ES2330418T3/en not_active Expired - Lifetime
- 2002-07-17 RU RU2004105265/15A patent/RU2321406C9/en not_active IP Right Cessation
- 2002-07-17 EP EP06017257A patent/EP1733728A3/en not_active Withdrawn
- 2002-07-17 CN CNA028144759A patent/CN1649593A/en active Pending
- 2002-07-17 UA UA2004021279A patent/UA76997C2/en unknown
- 2002-07-17 MX MXPA04000675A patent/MXPA04000675A/en active IP Right Grant
- 2002-07-17 HU HU0500734A patent/HUP0500734A3/en unknown
- 2002-07-17 EE EEP200400056A patent/EE200400056A/en unknown
- 2002-07-17 CZ CZ2004128A patent/CZ2004128A3/en unknown
- 2002-07-17 US US10/483,462 patent/US6930108B2/en not_active Expired - Fee Related
- 2002-07-17 WO PCT/EP2002/007959 patent/WO2003011262A2/en not_active Ceased
- 2002-07-17 KR KR10-2004-7001050A patent/KR20040032865A/en not_active Ceased
- 2002-07-17 BR BR0211359-7A patent/BR0211359A/en not_active IP Right Cessation
- 2002-07-17 PL PL02373392A patent/PL373392A1/en not_active Application Discontinuation
- 2002-07-17 IL IL15984002A patent/IL159840A0/en unknown
- 2002-07-17 CA CA002454414A patent/CA2454414A1/en not_active Abandoned
- 2002-07-17 EP EP02748858A patent/EP1474150B1/en not_active Expired - Lifetime
- 2002-07-17 NZ NZ530703A patent/NZ530703A/en unknown
- 2002-07-17 AT AT02748858T patent/ATE442144T1/en not_active IP Right Cessation
- 2002-07-17 SK SK44-2004A patent/SK442004A3/en not_active Application Discontinuation
- 2002-07-17 DE DE50213840T patent/DE50213840D1/en not_active Expired - Fee Related
- 2002-07-17 AU AU2002319296A patent/AU2002319296B2/en not_active Ceased
- 2002-07-17 HR HRP20040065 patent/HRP20040065A2/en not_active Application Discontinuation
-
2004
- 2004-01-14 BG BG108533A patent/BG108533A/en unknown
- 2004-01-19 EC EC2004004956A patent/ECSP044956A/en unknown
- 2004-01-22 NO NO20040294A patent/NO20040294L/en not_active Application Discontinuation
- 2004-01-22 MA MA27497A patent/MA26128A1/en unknown
- 2004-02-23 CO CO04015666A patent/CO5560536A2/en not_active Application Discontinuation
-
2005
- 2005-06-17 US US11/156,082 patent/US7276504B2/en not_active Expired - Fee Related
-
2007
- 2007-10-01 US US11/906,382 patent/US20080085897A1/en not_active Abandoned
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