[go: up one dir, main page]

AU2002316942A1 - Microstructures and use thereof for the directed evolution of biomolecules - Google Patents

Microstructures and use thereof for the directed evolution of biomolecules

Info

Publication number
AU2002316942A1
AU2002316942A1 AU2002316942A AU2002316942A AU2002316942A1 AU 2002316942 A1 AU2002316942 A1 AU 2002316942A1 AU 2002316942 A AU2002316942 A AU 2002316942A AU 2002316942 A AU2002316942 A AU 2002316942A AU 2002316942 A1 AU2002316942 A1 AU 2002316942A1
Authority
AU
Australia
Prior art keywords
microstructures
biomolecules
directed evolution
evolution
directed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002316942A
Other versions
AU2002316942B2 (en
Inventor
Ulrich Kettling
Andre Koltermann
Markus Rarbach
Jens Stephan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01113331A external-priority patent/EP1262545A1/en
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of AU2002316942A1 publication Critical patent/AU2002316942A1/en
Application granted granted Critical
Publication of AU2002316942B2 publication Critical patent/AU2002316942B2/en
Assigned to BAYER SCHERING PHARMA AKTIENGESELLSCHAFT reassignment BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Request for Assignment Assignors: DIREVO BIOTECH AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002316942A 2001-05-31 2002-05-31 Microstructures and use thereof for the directed evolution of biomolecules Ceased AU2002316942B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01113331.1 2001-05-31
EP01113331A EP1262545A1 (en) 2001-05-31 2001-05-31 Microstructures and the use thereof in the targeted evolution of biomolecules
PCT/EP2002/005971 WO2002097130A2 (en) 2001-05-31 2002-05-31 Microstructures and use thereof for the directed evolution of biomolecules

Publications (2)

Publication Number Publication Date
AU2002316942A1 true AU2002316942A1 (en) 2003-05-08
AU2002316942B2 AU2002316942B2 (en) 2008-02-21

Family

ID=8177600

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002316942A Ceased AU2002316942B2 (en) 2001-05-31 2002-05-31 Microstructures and use thereof for the directed evolution of biomolecules

Country Status (10)

Country Link
US (2) US20060147909A1 (en)
EP (2) EP1262545A1 (en)
AT (1) ATE401397T1 (en)
AU (1) AU2002316942B2 (en)
CA (1) CA2449020A1 (en)
DE (1) DE50212513D1 (en)
DK (1) DK1390492T3 (en)
ES (1) ES2310207T3 (en)
PT (1) PT1390492E (en)
WO (1) WO2002097130A2 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10533998B2 (en) 2008-07-18 2020-01-14 Bio-Rad Laboratories, Inc. Enzyme quantification
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
DE10322942A1 (en) * 2003-05-19 2004-12-09 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Device for positioning and discharging fluid compartments embedded in the separation medium
JP4698613B2 (en) * 2004-01-26 2011-06-08 プレジデント アンド フェロウズ オブ ハーバード カレッジ Fluid delivery system and method
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
JP4766046B2 (en) * 2005-04-01 2011-09-07 コニカミノルタエムジー株式会社 Micro total analysis system, inspection chip, and inspection method
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2021113A2 (en) 2006-05-11 2009-02-11 Raindance Technologies, Inc. Microfluidic devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP3536396B1 (en) 2006-08-07 2022-03-30 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
WO2010111231A1 (en) 2009-03-23 2010-09-30 Raindance Technologies, Inc. Manipulation of microfluidic droplets
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
CA2789425C (en) 2010-02-12 2020-04-28 Raindance Technologies, Inc. Digital analyte analysis with polymerase error correction
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
EP3412778A1 (en) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Methods for forming mixed droplets
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US20140199764A1 (en) * 2011-05-09 2014-07-17 President And Fellows Of Harvard College Microfluidic module and uses thereof
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
WO2014158367A1 (en) 2013-03-13 2014-10-02 Opko Diagnostics, Llc Mixing of fluids in fluidic systems
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US11193176B2 (en) 2013-12-31 2021-12-07 Bio-Rad Laboratories, Inc. Method for detecting and quantifying latent retroviral RNA species
MX2017007576A (en) 2014-12-12 2018-03-09 Opko Diagnostics Llc Fluidic systems comprising an incubation channel, including fluidic systems formed by molding.
US10260064B2 (en) * 2015-03-26 2019-04-16 The Johns Hopkins University Programmed droplet rupture for directed evolution
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710256B1 (en) * 1993-09-24 1997-08-01 Gilles Billet Dental prosthesis with composite support shell and resin coating, piece of prepreg fabric, method and machine for manufacturing this prosthesis.
AU2793295A (en) * 1994-06-17 1996-01-15 Evotec Biosystems Gmbh Process and device for selectively extracting components from complex mixtures
FI102945B (en) * 1995-02-24 1999-03-31 Stick Tech Oy Prepreg, a process for its preparation, a composite based on the aforementioned prereg and its use
DE19529036A1 (en) * 1995-08-08 1997-03-13 Huels Chemische Werke Ag Biocompatible composite material for use on implants, esp. dental implants
US6130098A (en) * 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6207031B1 (en) * 1997-09-15 2001-03-27 Whitehead Institute For Biomedical Research Methods and apparatus for processing a sample of biomolecular analyte using a microfabricated device
US6641998B2 (en) * 1997-10-10 2003-11-04 Stratagene Methods and kits to enrich for desired nucleic acid sequences
DE60031506T2 (en) * 1999-01-08 2007-08-23 Applera Corp., Foster City FASERMATRIX FOR MEASURING CHEMICALS, AND METHOD FOR THE PRODUCTION AND USE THEREOF
DE19950385A1 (en) * 1999-01-29 2000-08-03 Max Planck Gesellschaft Process for the isolation of apoptosis-inducing DNA sequences and detection system
AU3769000A (en) * 1999-03-22 2000-10-09 Pangene Corporation High-throughput gene cloning and phenotypic screening
SG121902A1 (en) * 2000-01-11 2006-05-26 Maxygen Inc Integrated systems for diversity generation and screening

Similar Documents

Publication Publication Date Title
AU2002316942A1 (en) Microstructures and use thereof for the directed evolution of biomolecules
WO2002097130A3 (en) Microstructures and use thereof for the directed evolution of biomolecules
AU2002364528A1 (en) Bio-implant and method of making the same
EP1423120A4 (en) 2h-phthalazin-1-ones and methods for use thereof
AU2002340167A1 (en) Anti-hla-dr antibodies and the methods of using thereof
AU2002362248A1 (en) Spray member and method for using the same
AU2001256373A1 (en) Syringe and method for the use thereof
AU2002239933A1 (en) Antineoplastic polyalkoxyalkylsiloxanes and methods of use thereof
GB0111218D0 (en) Assays methods and means
AU2002359694A1 (en) Compounds and methods
AU2002312373A1 (en) Structural and cytoskeleton-associated proteins
AU2002341828A1 (en) Enhanced proteins and methods for their use
AU5565401A (en) Materials and methods for the treatment of depression
AU2001276258A1 (en) Ceramic component and the use thereof
AU2002342944A1 (en) Fiberboards and processes for the preparation thereof
AU2002237432A1 (en) Complex element micro-array and methods of use
AU2002320621A1 (en) Structural and cytoskeleton-associated proteins
AU2002250052A1 (en) Drawing and painting system
AU2002343516A1 (en) Structural and cytoskeleton-associated proteins
AU2002330299A1 (en) Antibody and use of the same
AU2002256588A1 (en) Catalase-inactivating compounds and the use thereof
AU2002338089A1 (en) Antibody and use thereof
AU2002315593A1 (en) Integrated electrokinetic devices and methods of manufacture
AU2002333371A1 (en) Novel 4-aminofuropyrimidines and the use thereof
AU2002311066A1 (en) Electrophoresis device and the use thereof