[go: up one dir, main page]

AU2002315857A1 - Cell proliferation inhibitors containing anti-glypican 3 antibody - Google Patents

Cell proliferation inhibitors containing anti-glypican 3 antibody

Info

Publication number
AU2002315857A1
AU2002315857A1 AU2002315857A AU2002315857A AU2002315857A1 AU 2002315857 A1 AU2002315857 A1 AU 2002315857A1 AU 2002315857 A AU2002315857 A AU 2002315857A AU 2002315857 A AU2002315857 A AU 2002315857A AU 2002315857 A1 AU2002315857 A1 AU 2002315857A1
Authority
AU
Australia
Prior art keywords
glypican
antibody
cell proliferation
containing anti
inhibitors containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002315857A
Other versions
AU2002315857B2 (en
Inventor
Hiroyuki Aburatani
Tetsuo Nakamura
Masayuki Tsuchiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority claimed from PCT/JP2002/006237 external-priority patent/WO2003000883A1/en
Publication of AU2002315857A1 publication Critical patent/AU2002315857A1/en
Assigned to KAISHA, CHUGAI, PERSEUS PROTEOMICS INC. reassignment KAISHA, CHUGAI Request for Assignment Assignors: Aburanti, Hiroyuki, KAISHA, CHUGAI
Assigned to KAISHA, CHUGAI reassignment KAISHA, CHUGAI Request for Assignment Assignors: KAISHA, CHUGAI, PERSEUS PROTEOMICS INC.
Priority to AU2007201255A priority Critical patent/AU2007201255B2/en
Application granted granted Critical
Publication of AU2002315857B2 publication Critical patent/AU2002315857B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

AU2002315857A 2001-06-22 2002-06-21 Cell proliferation inhibitors containing anti-glypican 3 antibody Expired AU2002315857B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2007201255A AU2007201255B2 (en) 2001-06-22 2007-03-22 Cell proliferation inhibitors containing anti-glypican 3 antibody

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001-189443 2001-06-22
JP2001189443 2001-06-22
PCT/JP2002/006237 WO2003000883A1 (en) 2001-06-22 2002-06-21 Cell proliferation inhibitors containing anti-glypican 3 antibody

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2007201255A Division AU2007201255B2 (en) 2001-06-22 2007-03-22 Cell proliferation inhibitors containing anti-glypican 3 antibody

Publications (2)

Publication Number Publication Date
AU2002315857A1 true AU2002315857A1 (en) 2003-06-19
AU2002315857B2 AU2002315857B2 (en) 2007-07-26

Family

ID=19028362

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2002315857A Expired AU2002315857B2 (en) 2001-06-22 2002-06-21 Cell proliferation inhibitors containing anti-glypican 3 antibody
AU2007201255A Expired AU2007201255B2 (en) 2001-06-22 2007-03-22 Cell proliferation inhibitors containing anti-glypican 3 antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2007201255A Expired AU2007201255B2 (en) 2001-06-22 2007-03-22 Cell proliferation inhibitors containing anti-glypican 3 antibody

Country Status (14)

Country Link
US (3) US20040236080A1 (en)
EP (3) EP1411118B1 (en)
JP (7) JP4281869B2 (en)
KR (3) KR100877176B1 (en)
CN (2) CN1314803C (en)
AT (2) ATE407204T1 (en)
AU (2) AU2002315857B2 (en)
CA (1) CA2451493C (en)
CY (1) CY1113854T1 (en)
DE (2) DE60237929D1 (en)
DK (2) DK2208784T3 (en)
ES (3) ES2399028T3 (en)
PT (2) PT2208784E (en)
WO (1) WO2003000883A1 (en)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361336B1 (en) * 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
US20040236080A1 (en) * 2001-06-22 2004-11-25 Hiroyuki Aburatani Cell proliferation inhibitors containing anti-glypican 3 antibody
PT1506406E (en) * 2002-05-23 2009-06-03 Sunnybrook Health Sciences Ct DIAGNOSIS OF HEPATOCELLULAR CARCINOMA
AU2002338020A1 (en) * 2002-09-04 2004-03-29 Chugai Seiyaku Kabushiki Kaisha Antibody against blood-solubilized n-terminal peptide in gpc3
EP1671645A4 (en) * 2003-09-04 2007-07-25 Chugai Pharmaceutical Co Ltd REMEDY AND DETECTION MEDICINE FOR CANCER OF BILARY TRACT CANCER
PT1674111E (en) * 2004-07-09 2010-12-15 Chugai Pharmaceutical Co Ltd Anti-glypican 3 antibody
DK1800693T3 (en) 2004-08-24 2013-10-21 Chugai Pharmaceutical Co Ltd Adjuvant therapy using anti-glypican 3 antibodies
WO2006046751A1 (en) * 2004-10-26 2006-05-04 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody having modified sugar chain
WO2006106905A1 (en) 2005-03-31 2006-10-12 Chugai Seiyaku Kabushiki Kaisha Process for production of polypeptide by regulation of assembly
JPWO2007015529A1 (en) 2005-08-03 2009-02-19 パナソニック株式会社 Base station apparatus, communication terminal apparatus, and multicarrier communication method
US20070087005A1 (en) * 2005-10-14 2007-04-19 Lazar Gregory A Anti-glypican-3 antibody
US7723043B2 (en) * 2006-01-04 2010-05-25 Picobella, Lp Methods for screening for prostate cancer
WO2007114319A1 (en) 2006-03-31 2007-10-11 Chugai Seiyaku Kabushiki Kaisha Method for control of blood kinetics of antibody
US9670269B2 (en) 2006-03-31 2017-06-06 Chugai Seiyaku Kabushiki Kaisha Methods of modifying antibodies for purification of bispecific antibodies
AU2008275985B2 (en) 2007-07-17 2013-09-19 E. R. Squibb & Sons, L.L.C. Monoclonal antibodies against Glypican-3
EP3127921A1 (en) 2007-09-26 2017-02-08 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substition in cdr
CN101874041B (en) 2007-09-26 2013-06-19 中外制药株式会社 Modified antibody constant region
CA2700986A1 (en) 2007-09-28 2009-04-02 Chugai Seiyaku Kabushiki Kaisha Anti-glypican-3 antibody having improved kinetics in plasma
TWI548418B (en) 2007-12-05 2016-09-11 Chugai Pharmaceutical Co Ltd Anti-NR10 / IL-31RA antibody and its use
CL2009000647A1 (en) * 2008-04-04 2010-06-04 Chugai Pharmaceutical Co Ltd Pharmaceutical composition for treating or preventing liver cancer comprising a combination of a chemotherapeutic agent and an anti-glypican 3 antibody; agent for attenuating a side effect comprising said antibody; method of treating or preventing liver cancer of a subject.
EP2708559B1 (en) * 2008-04-11 2018-03-28 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
TWI440469B (en) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
EP3674317B1 (en) 2009-03-19 2024-12-11 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
WO2010107110A1 (en) 2009-03-19 2010-09-23 中外製薬株式会社 Antibody constant region variant
US10150808B2 (en) 2009-09-24 2018-12-11 Chugai Seiyaku Kabushiki Kaisha Modified antibody constant regions
EP2543730B1 (en) 2010-03-04 2018-10-31 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
HRP20180421T1 (en) 2010-11-17 2018-04-20 Chugai Seiyaku Kabushiki Kaisha Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii
TWI654204B (en) 2010-11-30 2019-03-21 中外製藥股份有限公司 Antibody with calcium-dependent antigen binding ability
CA2819530C (en) 2010-11-30 2023-01-10 Chugai Seiyaku Kabushiki Kaisha Cytotoxicity-inducing therapeutic agent
US20120190049A1 (en) * 2010-12-10 2012-07-26 University Of Washington Through Its Center For Commercialization Glypican-3 targeting of liver cancer cells using multifunctional nanoparticles
WO2012115241A1 (en) 2011-02-25 2012-08-30 中外製薬株式会社 Fcγriib-specific fc antibody
EP3825325A3 (en) 2011-03-30 2021-10-13 Chugai Seiyaku Kabushiki Kaisha Retention of antigen-binding molecules in blood plasma and method for modifying immunogenicity
KR20200096692A (en) 2011-09-30 2020-08-12 추가이 세이야쿠 가부시키가이샤 Antigen-binding molecule for promoting elimination of antigens
CN104093424A (en) 2011-09-30 2014-10-08 中外制药株式会社 Antigen-binding molecules that induce an immune response against a target antigen
TW201817744A (en) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 Therapeutic antigen-binding molecule having an FcRn binding domain that promotes antigen clearance
WO2013047748A1 (en) 2011-09-30 2013-04-04 中外製薬株式会社 Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
US20150299313A1 (en) 2011-10-05 2015-10-22 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule for promoting clearance from plasma of antigen comprising suger chain receptor-binding domain
JP6138108B2 (en) 2012-02-24 2017-05-31 中外製薬株式会社 Antigen-binding molecule that promotes disappearance of antigen via FcγRIIB
CN104487457B (en) 2012-05-30 2018-01-26 中外制药株式会社 target tissue specific antigen binding molecule
CN104520331B (en) 2012-06-01 2018-09-07 美国政府(由卫生和人类服务部的部长所代表) High-affinity monoclonal antibody to Glypican 3 and use thereof
TWI693073B (en) 2012-12-21 2020-05-11 日商中外製藥股份有限公司 Therapeutic agent for GPC3 target is the effective therapeutic agent for GPC3 target administered to patients
EP3557260B1 (en) 2012-12-21 2022-05-18 Chugai Seiyaku Kabushiki Kaisha Gpc3-targeting drug which is administered to patient responsive to gpc3-targeting drug therapy
RU2730594C2 (en) 2013-09-27 2020-08-24 Чугаи Сейяку Кабусики Кайся Method of producing a polypeptide heteromultiters
BR112016012094A2 (en) 2013-12-04 2017-09-26 Chugai Pharmaceutical Co Ltd antigen binding molecules, whose antigen binding activity varies according to the concentration of compounds and libraries of said molecules
KR102409014B1 (en) 2014-05-08 2022-06-14 추가이 세이야쿠 가부시키가이샤 Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
US9926377B2 (en) * 2014-05-22 2018-03-27 Genentech, Inc. Anti-GPC3 antibodies and immunoconjugates
MA40764A (en) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd THERAPEUTIC AGENT INDUCING CYTOTOXICITY
CN104829704B (en) * 2014-12-15 2016-08-17 河北省科学院生物研究所 A kind of glypican GPC3 protein fragments and application thereof and the hybridoma cell strain of preparation
CA2963760A1 (en) 2014-12-19 2016-06-23 Yoshinao Ruike Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
ES2899894T3 (en) 2014-12-19 2022-03-15 Chugai Pharmaceutical Co Ltd Anti-C5 antibodies and methods of use
AU2015376851B2 (en) * 2015-01-16 2020-07-09 Minomic International Ltd. Glypican epitopes and uses thereof
MX2017008978A (en) 2015-02-05 2017-10-25 Chugai Pharmaceutical Co Ltd Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof.
ES2967627T3 (en) 2015-02-27 2024-05-03 Chugai Pharmaceutical Co Ltd Composition to treat diseases related to IL-6
WO2016159213A1 (en) 2015-04-01 2016-10-06 中外製薬株式会社 Method for producing polypeptide hetero-oligomer
WO2017002934A1 (en) 2015-07-01 2017-01-05 中外製薬株式会社 Gpc3-targeted therapeutic agent administered to patient in whom gpc3-targetd therapeutic ag
IL257324B (en) * 2015-08-03 2022-08-01 Carsgen Therapeutics Ltd Antibody against glypican-3 and application thereof
KR101796688B1 (en) 2015-10-29 2017-12-01 재단법인 목암생명과학연구소 Novel Antibody Against Glypican 3, and Pharmaceuitical Composition Comprising the Same
LT3373968T (en) * 2015-11-09 2024-07-10 The Children's Hospital Of Philadelphia Glypican 2 as a cancer marker and therapeutic target
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
SG11201803989WA (en) 2015-12-28 2018-06-28 Chugai Pharmaceutical Co Ltd Method for promoting efficiency of purification of fc region-containing polypeptide
AU2017233658B2 (en) 2016-03-14 2023-09-21 Chugai Seiyaku Kabushiki Kaisha Cell injury inducing therapeutic drug for use in cancer therapy
TW202248213A (en) 2016-03-15 2022-12-16 日商中外製藥股份有限公司 Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
MA44780A (en) 2016-04-28 2019-03-06 Chugai Pharmaceutical Co Ltd PREPARATION CONTAINING AN ANTIBODY
TWI831965B (en) 2016-08-05 2024-02-11 日商中外製藥股份有限公司 Compositions for the treatment or prevention of IL-8 related diseases
WO2018038046A1 (en) 2016-08-22 2018-03-01 中外製薬株式会社 Gene-modified non-human animal expressing human gpc3 polypeptide
IL266827B2 (en) 2016-11-28 2025-04-01 Chugai Pharmaceutical Co Ltd Ligand-binding molecule having adjustable ligand-binding activity, fusion protein thereof with a ligand, pharmaceutical compositions comprising them, and method of producing them
EP3620531A4 (en) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry METHOD FOR PREDICTING AND EVALUATING A THERAPEUTIC EFFECT IN DISEASES ASSOCIATED WITH IL-6 AND NEUTROPHILS
WO2019059411A1 (en) 2017-09-20 2019-03-28 Chugai Seiyaku Kabushiki Kaisha Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
MA50534A (en) 2017-11-01 2020-09-09 Chugai Pharmaceutical Co Ltd ANTIBODY VARIANT AND ISOFORM WITH REDUCED BIOLOGICAL ACTIVITY
TWI880235B (en) 2017-11-28 2025-04-11 日商中外製藥股份有限公司 Ligand-binding molecules capable of regulating ligand binding activity
AR114112A1 (en) 2018-02-15 2020-07-22 Seattle Genetics Inc GLIPICAN 3 ANTIBODIES AND CONJUGATES THEREOF
JPWO2019230868A1 (en) 2018-05-30 2021-06-24 中外製薬株式会社 Single domain antibody-containing ligand-binding molecule
MX2020013977A (en) 2018-06-22 2021-06-15 Kite Pharma Inc TRANSMEMBRANE CHIMERIC PROTEINS AND THEIR USES.
AU2019354395A1 (en) 2018-10-01 2021-05-06 Adicet Therapeutics, Inc. Compositions and methods regarding engineered and non-engineered γδ -T cells for treatment of solid tumors
KR20210080460A (en) 2018-10-23 2021-06-30 드래곤플라이 쎄라퓨틱스, 인크. Heterodimeric Fc-fused protein
WO2020189748A1 (en) 2019-03-19 2020-09-24 中外製薬株式会社 Antigen-binding molecule containing antigen-binding domain of which binding activity to antigen is changed depending on mta, and library for obtaining said antigen-binding domain
BR112021023735A2 (en) 2019-06-05 2022-01-04 Chugai Pharmaceutical Co Ltd Antibody cleavage site binding molecule
JP7716979B2 (en) 2019-06-05 2025-08-01 中外製薬株式会社 Protease substrates and polypeptides containing protease cleavage sequences
KR20220034792A (en) 2019-06-21 2022-03-18 카이트 파마 인코포레이티드 TGF-β receptors and methods of use thereof
AU2021260960A1 (en) 2020-04-22 2022-11-24 Dragonfly Therapeutics, Inc. Formulation, dosage regimen, and manufacturing process for heterodimeric Fc-fused proteins
AU2021317974A1 (en) 2020-07-31 2023-03-16 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical Composition comprising Cell Expressing Chimeric Receptor
JP2024537323A (en) * 2021-10-15 2024-10-10 コンセプト トゥー メディシン バイオテック カンパニー, リミテッド Anti-glypican 3 antibody
CN121358779A (en) 2023-06-16 2026-01-16 信立泰(成都)生物技术有限公司 Anti-GPC 3 antibody or antigen binding fragment and application thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04228089A (en) 1990-05-15 1992-08-18 Kanegafuchi Chem Ind Co Ltd Agent for treatment and prevention of hypercalcemia
AU7949394A (en) * 1993-11-19 1995-06-06 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human medulloblastomatous cell
ATE390933T1 (en) 1995-04-27 2008-04-15 Amgen Fremont Inc HUMAN ANTIBODIES AGAINST IL-8 DERIVED FROM IMMUNIZED XENOMICES
JP3587664B2 (en) 1996-10-04 2004-11-10 中外製薬株式会社 Reshaped human anti-HM1.24 antibody
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
JP4228089B2 (en) 1997-03-11 2009-02-25 株式会社ニコン Overcurrent detection mechanism and electronic flash device using the same
US7361336B1 (en) * 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
AU750453B2 (en) 1997-10-03 2002-07-18 Chugai Seiyaku Kabushiki Kaisha Natural human antibody
JP3445153B2 (en) 1998-06-04 2003-09-08 富士通株式会社 Device and method for temporary use of telephone numbers
CA2382587A1 (en) * 1999-08-23 2001-03-01 Chugai Seiyaku Kabushiki Kaisha Hm1.24 antigen expression potentiators
US20040236080A1 (en) 2001-06-22 2004-11-25 Hiroyuki Aburatani Cell proliferation inhibitors containing anti-glypican 3 antibody

Similar Documents

Publication Publication Date Title
AU2002315857A1 (en) Cell proliferation inhibitors containing anti-glypican 3 antibody
AU2001258771A1 (en) -secretase inhibitors
AU2002256895A1 (en) Anti-TRAIL-R antibodies
AU5170900A (en) Cell proliferation inhibitors
AU2002366160A1 (en) Zinc-alkaline battery containing lambda-mn02
AU2002365649A1 (en) Anti-dota antibody
AU2576501A (en) Protein kinase inhibitors
AU2002232034A1 (en) Substrate linked directed evolution (slide)
AU2002359464A1 (en) Angiopioetin related factors
AU3235100A (en) Prothease inhibitors
AU2002365354A1 (en) Case and case holder
AU2002222628A1 (en) Keratinocyte proliferation inhibitors
AU2002352778A1 (en) High-density cell microarrays for parallel functional determinations
AU2002310629A1 (en) Sample well plate
AU2001233965A1 (en) Novel cd23 inhibitors
AU2001290241A1 (en) Tumor cell proliferation inhibitors
AU2002255634A1 (en) Peptide deformylase inhibitors
AU2002349485A1 (en) Cell migration inhibitor
AU2001253386A1 (en) Haplotypes of the impdh2 gene
AU2002344411A1 (en) Cell proliferation inhibitor
AU2002233669A1 (en) Casoase 3 inhibitors
AU2002237186A1 (en) Cell proliferation factor fwa267
AU2002237184A1 (en) Cell proliferation factor fwap10576
AU2002232410A1 (en) Inverted container tape
AUPR506501A0 (en) T cell subset