AU2002311322A1 - Processing Method of Lactonization in the Preparation of Statins - Google Patents
Processing Method of Lactonization in the Preparation of StatinsInfo
- Publication number
- AU2002311322A1 AU2002311322A1 AU2002311322A AU2002311322A AU2002311322A1 AU 2002311322 A1 AU2002311322 A1 AU 2002311322A1 AU 2002311322 A AU2002311322 A AU 2002311322A AU 2002311322 A AU2002311322 A AU 2002311322A AU 2002311322 A1 AU2002311322 A1 AU 2002311322A1
- Authority
- AU
- Australia
- Prior art keywords
- lactonization
- statins
- preparation
- processing method
- processing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- 238000007273 lactonization reaction Methods 0.000 title 1
- 238000003672 processing method Methods 0.000 title 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2001-0075991A KR100423892B1 (en) | 2001-12-03 | 2001-12-03 | A new process of lactonization in the preparation of statins |
| KP2001-0075991 | 2001-12-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2002311322A1 true AU2002311322A1 (en) | 2003-06-12 |
| AU2002311322B2 AU2002311322B2 (en) | 2005-06-30 |
| AU2002311322B8 AU2002311322B8 (en) | 2005-10-27 |
Family
ID=36129249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002311322A Ceased AU2002311322B8 (en) | 2001-12-03 | 2002-12-02 | Processing Method of Lactonization in the Preparation of Statins |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6906204B2 (en) |
| EP (1) | EP1316552B1 (en) |
| JP (1) | JP3802481B2 (en) |
| KR (1) | KR100423892B1 (en) |
| CN (1) | CN1197854C (en) |
| AT (1) | ATE318264T1 (en) |
| AU (1) | AU2002311322B8 (en) |
| BR (1) | BR0204943A (en) |
| CA (1) | CA2413235C (en) |
| DE (1) | DE60209289T2 (en) |
| MX (1) | MXPA02011967A (en) |
| WO (1) | WO2003048149A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100502834B1 (en) * | 2002-03-25 | 2005-07-20 | 보령제약 주식회사 | The preparation method of simvastatin by improved process of lactonization and its purification process |
| ATE414071T1 (en) * | 2004-03-30 | 2008-11-15 | Lupin Ltd | IMPROVED METHOD FOR PRODUCING 4-HYDROXYPYRAN-2-ONE DERIVATIVES |
| EP2597092A1 (en) | 2011-11-24 | 2013-05-29 | Sterling Biotech Limited | A process for purification of lovastatin |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2053000C (en) * | 1990-10-15 | 1995-08-29 | Michael J. Conder | Biosynthetic production of 6(r)-[2-(8(s)-hydroxy-2(s), 6(r)-dimethyl-1,2,6,7,8,8a(r)-hexahydronaphthyl)-ethyl]-4 (r)-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-one triol acid by enzymatic hydrolysis of lovastatin acid using an enzyme derived from__lonostachys compactiuscula |
| NZ245713A (en) * | 1992-02-10 | 1994-12-22 | Novopharm Ltd | Production of the antibiotic lovastatin from genetically engineered aspergillus strains |
| PT971913E (en) | 1997-01-28 | 2003-08-29 | Plus Chemicals Bv | PROCESS FOR THE PRODUCTION OF SEMI-SYNTHETIC STATINES THROUGH NEW INTERMEDIARIES |
| IN186879B (en) * | 1997-10-28 | 2001-12-01 | Ranbaxy Lab Ltd | |
| IN186880B (en) * | 1997-10-28 | 2001-12-01 | Ranbaxy Lab Ltd | |
| US6380401B1 (en) | 1999-10-27 | 2002-04-30 | Merck & Co., Inc. | Lactonization process |
| JP2004520445A (en) * | 2001-05-18 | 2004-07-08 | オーロビンド ファーマ リミテッド | A lactonization method for producing simvastatin |
-
2001
- 2001-12-03 KR KR10-2001-0075991A patent/KR100423892B1/en not_active Expired - Fee Related
-
2002
- 2002-11-11 WO PCT/KR2002/002095 patent/WO2003048149A1/en not_active Ceased
- 2002-11-14 US US10/295,300 patent/US6906204B2/en not_active Expired - Fee Related
- 2002-11-29 CA CA002413235A patent/CA2413235C/en not_active Expired - Fee Related
- 2002-11-29 CN CNB021530378A patent/CN1197854C/en not_active Expired - Fee Related
- 2002-12-02 JP JP2002350255A patent/JP3802481B2/en not_active Expired - Fee Related
- 2002-12-02 BR BR0204943-0A patent/BR0204943A/en active Search and Examination
- 2002-12-02 MX MXPA02011967A patent/MXPA02011967A/en active IP Right Grant
- 2002-12-02 AU AU2002311322A patent/AU2002311322B8/en not_active Ceased
- 2002-12-03 AT AT02026916T patent/ATE318264T1/en not_active IP Right Cessation
- 2002-12-03 DE DE60209289T patent/DE60209289T2/en not_active Expired - Lifetime
- 2002-12-03 EP EP02026916A patent/EP1316552B1/en not_active Expired - Lifetime
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