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AU2002311322A1 - Processing Method of Lactonization in the Preparation of Statins - Google Patents

Processing Method of Lactonization in the Preparation of Statins

Info

Publication number
AU2002311322A1
AU2002311322A1 AU2002311322A AU2002311322A AU2002311322A1 AU 2002311322 A1 AU2002311322 A1 AU 2002311322A1 AU 2002311322 A AU2002311322 A AU 2002311322A AU 2002311322 A AU2002311322 A AU 2002311322A AU 2002311322 A1 AU2002311322 A1 AU 2002311322A1
Authority
AU
Australia
Prior art keywords
lactonization
statins
preparation
processing method
processing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002311322A
Other versions
AU2002311322B2 (en
AU2002311322B8 (en
Inventor
Hong-Suk Cho
Kwang-Do Choi
Jin-Wan Kim
Kwang-Hyeg Lee
Sang-Ho Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HK Inno N Corp
Original Assignee
CJ Healthcare Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2001-0075991A external-priority patent/KR100423892B1/en
Application filed by CJ Healthcare Corp filed Critical CJ Healthcare Corp
Publication of AU2002311322A1 publication Critical patent/AU2002311322A1/en
Publication of AU2002311322B2 publication Critical patent/AU2002311322B2/en
Application granted granted Critical
Publication of AU2002311322B8 publication Critical patent/AU2002311322B8/en
Assigned to CJ HEALTHCARE CORPORATION reassignment CJ HEALTHCARE CORPORATION Request for Assignment Assignors: CJ CORP.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002311322A 2001-12-03 2002-12-02 Processing Method of Lactonization in the Preparation of Statins Ceased AU2002311322B8 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2001-0075991A KR100423892B1 (en) 2001-12-03 2001-12-03 A new process of lactonization in the preparation of statins
KP2001-0075991 2001-12-03

Publications (3)

Publication Number Publication Date
AU2002311322A1 true AU2002311322A1 (en) 2003-06-12
AU2002311322B2 AU2002311322B2 (en) 2005-06-30
AU2002311322B8 AU2002311322B8 (en) 2005-10-27

Family

ID=36129249

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002311322A Ceased AU2002311322B8 (en) 2001-12-03 2002-12-02 Processing Method of Lactonization in the Preparation of Statins

Country Status (12)

Country Link
US (1) US6906204B2 (en)
EP (1) EP1316552B1 (en)
JP (1) JP3802481B2 (en)
KR (1) KR100423892B1 (en)
CN (1) CN1197854C (en)
AT (1) ATE318264T1 (en)
AU (1) AU2002311322B8 (en)
BR (1) BR0204943A (en)
CA (1) CA2413235C (en)
DE (1) DE60209289T2 (en)
MX (1) MXPA02011967A (en)
WO (1) WO2003048149A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100502834B1 (en) * 2002-03-25 2005-07-20 보령제약 주식회사 The preparation method of simvastatin by improved process of lactonization and its purification process
ATE414071T1 (en) * 2004-03-30 2008-11-15 Lupin Ltd IMPROVED METHOD FOR PRODUCING 4-HYDROXYPYRAN-2-ONE DERIVATIVES
EP2597092A1 (en) 2011-11-24 2013-05-29 Sterling Biotech Limited A process for purification of lovastatin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053000C (en) * 1990-10-15 1995-08-29 Michael J. Conder Biosynthetic production of 6(r)-[2-(8(s)-hydroxy-2(s), 6(r)-dimethyl-1,2,6,7,8,8a(r)-hexahydronaphthyl)-ethyl]-4 (r)-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-one triol acid by enzymatic hydrolysis of lovastatin acid using an enzyme derived from__lonostachys compactiuscula
NZ245713A (en) * 1992-02-10 1994-12-22 Novopharm Ltd Production of the antibiotic lovastatin from genetically engineered aspergillus strains
PT971913E (en) 1997-01-28 2003-08-29 Plus Chemicals Bv PROCESS FOR THE PRODUCTION OF SEMI-SYNTHETIC STATINES THROUGH NEW INTERMEDIARIES
IN186879B (en) * 1997-10-28 2001-12-01 Ranbaxy Lab Ltd
IN186880B (en) * 1997-10-28 2001-12-01 Ranbaxy Lab Ltd
US6380401B1 (en) 1999-10-27 2002-04-30 Merck & Co., Inc. Lactonization process
JP2004520445A (en) * 2001-05-18 2004-07-08 オーロビンド ファーマ リミテッド A lactonization method for producing simvastatin

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