AU2002302419A1 - Substituted Pyrazolopyrimidines and thiazolopyrimidines used as analgesics - Google Patents

Substituted Pyrazolopyrimidines and thiazolopyrimidines used as analgesics

Info

Publication number: AU2002302419A1
Authority: AU; Australia
Prior art keywords: thiazolopyrimidines; analgesics; substituted pyrazolopyrimidines; pyrazolopyrimidines; substituted
Prior art date: 2001-03-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2002302419A

Other versions

AU2002302419B2 (en

Inventor

Miriam Dissen-De Groote

Martin Fuhr

Matthias Gerlach

Adriaan P Ijzerman

Utz-Peter Jagusch

Corinna Maul

Bernd Sundermann

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Gruenenthal GmbH

Original Assignee

Gruenenthal GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-14

Filing date

2002-03-13

Publication date

2003-03-20

2001-03-14 Priority claimed from DE2001112197 external-priority patent/DE10112197A1/en

2001-10-29 Priority claimed from DE2001153344 external-priority patent/DE10153344A1/en

2002-03-13 Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH

2002-03-13 Priority claimed from PCT/EP2002/002722 external-priority patent/WO2002072585A2/en

2003-03-20 Publication of AU2002302419A1 publication Critical patent/AU2002302419A1/en

2007-01-18 Application granted granted Critical

2007-01-18 Publication of AU2002302419B2 publication Critical patent/AU2002302419B2/en

2022-03-13 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
DE10112197.0		2001-03-14
DE2001112197 DE10112197A1 (en)	2001-03-14	2001-03-14	Medicaments for treating e.g. epilepsy, schizophrenia, neurodegenerative diseases or especially pain, comprising new or known pyrazolo-pyrimidine or thiazolo-pyrimidine compounds
DE10153344.6		2001-10-29
DE2001153344 DE10153344A1 (en)	2001-10-29	2001-10-29	Medicaments for treating e.g. epilepsy, schizophrenia, neurodegenerative diseases or especially pain, comprising new or known pyrazolo-pyrimidine or thiazolo-pyrimidine compounds
PCT/EP2002/002722 WO2002072585A2 (en)	2001-03-14	2002-03-13	Substituted pyrazolopyrimidines and thiazolopyrimidines used as analgesics

Publications (2)

Publication Number	Publication Date
AU2002302419A1 true AU2002302419A1 (en)	2003-03-20
AU2002302419B2 AU2002302419B2 (en)	2007-01-18

Family

ID=26008763

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002302419A Ceased AU2002302419B2 (en)	2001-03-14	2002-03-13	Substituted Pyrazolopyrimidines and thiazolopyrimidines used as analgesics

Country Status (24)

Country	Link
US (1)	US7135568B2 (en)
EP (2)	EP1637533B1 (en)
JP (1)	JP2004527508A (en)
KR (1)	KR20030082982A (en)
CN (1)	CN1318422C (en)
AT (2)	ATE404568T1 (en)
AU (1)	AU2002302419B2 (en)
BR (1)	BR0208244A (en)
CA (1)	CA2440760C (en)
CY (1)	CY1105507T1 (en)
CZ (1)	CZ20032474A3 (en)
DE (2)	DE50212652D1 (en)
DK (1)	DK1368355T3 (en)
ES (2)	ES2263779T3 (en)
HU (1)	HUP0401211A3 (en)
IL (2)	IL157895A0 (en)
MX (1)	MXPA03008291A (en)
NO (1)	NO20034031L (en)
NZ (2)	NZ528639A (en)
PL (1)	PL364388A1 (en)
PT (1)	PT1368355E (en)
RU (1)	RU2003129060A (en)
SK (1)	SK11542003A3 (en)
WO (1)	WO2002072585A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004017908A2 (en) *	2002-08-26	2004-03-04	Takeda Pharmaceutical Company Limited	Calcium receptor modulating compound and use thereof
US7468376B2 (en) *	2003-02-27	2008-12-23	Palau Pharma, S.A.	Pyrazolopyridine derivates
GB0404434D0 (en) *	2004-02-27	2004-03-31	Novartis Ag	Organic compounds
US20080287405A1 (en) *	2004-05-14	2008-11-20	Thannickal Victor J	Compositions and Methods Relating to Protein Kinase Inhibitors
AR050188A1 (en) *	2004-08-03	2006-10-04	Uriach Y Compania S A J	CONDENSED HETEROCICLIC COMPOUNDS USED IN THERAPY AS INHIBITORS OF P38 KINASES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP1736475A1 (en) *	2005-06-21	2006-12-27	Ferrer Internacional, S.A.	Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates
KR100838692B1 (en)	2007-07-11	2008-06-16	한국화학연구원	7- (3 ', 4'-dialkoxyphenyl) -4,5,6,7-tetrahydropyrazolo [1,5-a] pyrimidine compound, preparation method thereof and asthma and chronic obstructive pulmonary disease comprising the same Pharmaceutical compositions for the treatment and prevention of inflammation-related diseases, including arthritis, atopic dermatitis, cancer and brain diseases
RU2374249C1 (en) *	2008-09-17	2009-11-27	Андрей Александрович Иващенко	SUBSTITUTED CYCLOALKANO[e OR d]PYRAZOLO[1,5-a]PYRIMIDINE-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHOD OF PRODUCING SAID COMPOUNDS AND USE
WO2009093210A2 (en) *	2008-01-24	2009-07-30	Alla Chem, Llc	SUBSTITUTED CYCLOALCANO[e AND d] PYRAZOLO [1,5-a]PYRIMIDINES/ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS AND METHODS FOR PRODUCTION AND THE USE THEREOF
WO2009093209A2 (en) *	2008-01-24	2009-07-30	Alla Chem, Llc	2-ALKYLAMINO-3-ARYLSULFONYL-CYCLOALCANO [e OR d] PYRAZOLO [1,5-A]PYRIMIDINES / ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THE PRODUCTION AND THE USE THEREOF
RU2376291C1 (en) *	2008-05-07	2009-12-20	Андрей Александрович Иващенко	SUBSTITUTED 3,5-DIAMINO-4-SULFONYL-PYRAZOLES AND 2-AMINO-3-SULFONYL-PYRAZOLO-[1,5-a]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, METHODS FOR THEIR PRODUCTION AND USE
RU2369600C1 (en) *	2008-01-24	2009-10-10	Андрей Александрович Иващенко	SUBSTITUTED 4-SULPHONYL-PYRAZOLES AND 3-SULPHONYL-PYRAZOLO[1,5-a]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, MEDICINAL AGENT AND METHOD OF OBTAINING THEM
WO2010041983A1 (en) *	2008-10-06	2010-04-15	Алла Хем, Ллс	Substituted 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines, serotonin 5-ht6 receptor antagonists and methods for the production and use thereof
EP2379566A2 (en) *	2008-12-22	2011-10-26	Schering Corporation	Gamma secretase modulators
JO3407B1 (en) *	2012-05-31	2019-10-20	Eisai R&D Man Co Ltd	Tetrahydropyrazolopyrimidines
CN102775412B (en) *	2012-08-21	2013-05-01	四川大学	Sedative and soporific compound, and preparation method and application thereof
CN102977106B (en) *	2012-12-12	2014-12-10	中国药科大学	Kappa opioid agonist with peripheral analgesia effect
ES2687481T3 (en)	2013-03-15	2018-10-25	Chromocell Corporation	Sodium channel modulators for pain treatment
RU2016113156A (en) *	2013-09-10	2017-10-16	Хромоселл Корпорейшн	Sodium Channel Modulators for Pain and Diabetes
US10526323B2 (en)	2015-01-30	2020-01-07	Vanderbilt University	Indazole and azaindazole substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
JP6860559B2 (en)	2015-10-16	2021-04-14	エーザイ・アール・アンド・ディー・マネジメント株式会社	EP4 antagonist
WO2018133835A1 (en) *	2017-01-20	2018-07-26	National Institute Of Biological Sciences, Beijing	Nucleoside analogue regulating mammalian circadian rhythm
US12202832B2 (en)	2017-04-27	2025-01-21	Takeda Pharmaceutical Company Limited	Heterocyclic compounds having a calcium-sensing receptor antagonistic activity
US10919891B2 (en) *	2017-04-27	2021-02-16	Takeda Pharmaceutical Company Limited	Heterocyclic compound
CN113354644B (en) *	2020-03-04	2023-07-04	烟台药物研究所	Pyrazolopyrimidine compound used as DPP-IV inhibitor and application thereof
CN116023382B (en) *	2023-02-22	2025-09-23	北京师范大学	A method for synthesizing chiral tetrahydropyrazolo[1,5-a]pyrimidine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4847256A (en) *	1986-10-16	1989-07-11	American Cyanamid Company	4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines
EP0264773A1 (en)	1986-10-16	1988-04-27	American Cyanamid Company	4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines
NZ233641A (en) *	1989-05-16	1992-07-28	Merrell Dow Pharma	Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions
GB9206266D0 (en) *	1992-03-23	1992-05-06	Merck Sharp & Dohme	Therapeutic agents
FR2717812B1 (en) *	1994-03-28	1996-05-10	Rhone Poulenc Rorer Sa	Indeno [1,2-e] pyrazine-4-ones, their preparation and the drugs containing them.
FR2722786B1 (en) *	1994-07-20	1996-08-23	Rhone Poulenc Rorer Sa	DERIVATIVES OF 4-HYDROXY-3-PHENYL-INDENO (1,2-B) PYRIDINE-2 (1H) - ONE, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
DE4444815A1 (en) *	1994-12-15	1996-06-20	Merck Patent Gmbh	Thienopyridone
JP2003288537A (en)	2000-09-25	2003-10-10	Everyd.Com:Kk	Commodity delivery system and method
DE10112197A1 (en)	2001-03-14	2002-09-19	Gruenenthal Gmbh	Medicaments for treating e.g. epilepsy, schizophrenia, neurodegenerative diseases or especially pain, comprising new or known pyrazolo-pyrimidine or thiazolo-pyrimidine compounds

2002
- 2002-03-13 PT PT02729998T patent/PT1368355E/en unknown
- 2002-03-13 MX MXPA03008291A patent/MXPA03008291A/en active IP Right Grant
- 2002-03-13 CZ CZ20032474A patent/CZ20032474A3/en unknown
- 2002-03-13 DE DE50212652T patent/DE50212652D1/en not_active Expired - Lifetime
- 2002-03-13 AT AT05026811T patent/ATE404568T1/en not_active IP Right Cessation
- 2002-03-13 WO PCT/EP2002/002722 patent/WO2002072585A2/en not_active Ceased
- 2002-03-13 ES ES02729998T patent/ES2263779T3/en not_active Expired - Lifetime
- 2002-03-13 PL PL02364388A patent/PL364388A1/en not_active Application Discontinuation
- 2002-03-13 ES ES05026811T patent/ES2311920T3/en not_active Expired - Lifetime
- 2002-03-13 NZ NZ528639A patent/NZ528639A/en unknown
- 2002-03-13 CA CA2440760A patent/CA2440760C/en not_active Expired - Fee Related
- 2002-03-13 IL IL15789502A patent/IL157895A0/en unknown
- 2002-03-13 RU RU2003129060/04A patent/RU2003129060A/en not_active Application Discontinuation
- 2002-03-13 HU HU0401211A patent/HUP0401211A3/en unknown
- 2002-03-13 NZ NZ540574A patent/NZ540574A/en unknown
- 2002-03-13 SK SK1154-2003A patent/SK11542003A3/en unknown
- 2002-03-13 DK DK02729998T patent/DK1368355T3/en active
- 2002-03-13 KR KR10-2003-7011953A patent/KR20030082982A/en not_active Withdrawn
- 2002-03-13 AU AU2002302419A patent/AU2002302419B2/en not_active Ceased
- 2002-03-13 CN CNB028096886A patent/CN1318422C/en not_active Expired - Fee Related
- 2002-03-13 EP EP05026811A patent/EP1637533B1/en not_active Expired - Lifetime
- 2002-03-13 BR BR0208244-6A patent/BR0208244A/en not_active Application Discontinuation
- 2002-03-13 AT AT02729998T patent/ATE328886T1/en not_active IP Right Cessation
- 2002-03-13 JP JP2002571501A patent/JP2004527508A/en active Pending
- 2002-03-13 DE DE50207103T patent/DE50207103D1/en not_active Expired - Lifetime
- 2002-03-13 EP EP02729998A patent/EP1368355B1/en not_active Expired - Lifetime
2003
- 2003-09-11 NO NO20034031A patent/NO20034031L/en not_active Application Discontinuation
- 2003-09-11 IL IL157895A patent/IL157895A/en not_active IP Right Cessation
- 2003-09-12 US US10/660,794 patent/US7135568B2/en not_active Expired - Fee Related
2006
- 2006-07-05 CY CY20061100930T patent/CY1105507T1/en unknown

Publication	Publication Date	Title
AU2002302419A1 (en)	2003-03-20	Substituted Pyrazolopyrimidines and thiazolopyrimidines used as analgesics
AU2002315389A1 (en)	2003-01-08	Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof
AU2002357119A1 (en)	2003-06-30	Mitocidal compositions and methods
AU2001287898A1 (en)	2002-04-02	Pyrazolopyridines and pyrazolopyridazines as antidiabetics
AUPR510001A0 (en)	2001-06-14	Formulation and method
AU2002315388A1 (en)	2003-01-08	Novel phenylamino-pyrimidines and uses thereof
AU2002219135A1 (en)	2002-06-18	Substituted 2-anilino-benzimidazoles and the use thereof as NHE-inhibitors
AU2002219481A1 (en)	2002-07-24	Combination square
AU2002324450A1 (en)	2003-01-08	Novel pyridopyrimidines and uses thereof
AU2002357748A1 (en)	2003-06-10	Osteopontin-related compositions and methods
AU2002359694A1 (en)	2003-06-30	Compounds and methods
AU2002343489A1 (en)	2003-04-22	Nociceptin-based analgesics
AU2001100347A4 (en)	2002-01-24	IFCS firewatch
AU2002251543A1 (en)	2003-04-17	Novel atisane compound and use thereof
AU2002354083A1 (en)	2003-07-30	Cylinder-lock and flat-key combination
AU2002359869A1 (en)	2003-07-24	Pak5-related compositions and methods
AU2002327340A1 (en)	2003-02-17	3-pyridylether rerivatives and their use as analgesics
AU2002357687A1 (en)	2003-05-12	Pyrazolopyrimidines
SI1368355T1 (en)	2006-12-31	Substituted pyrazolopyrimidines and thiazolopyrimidines
AU2002258949A1 (en)	2002-12-03	Pyridopyrimidine compounds and their uses
AU2002228426A1 (en)	2002-08-28	Neurotonin and use thereof
AU2002247441A1 (en)	2002-10-15	Compounds and methods
AU2002245725A1 (en)	2002-10-15	Compounds and methods
AU2002335011A1 (en)	2003-04-22	Compounds and methods
AU2002254470A1 (en)	2002-10-15	Compounds and methods