AU2002365038A1 - Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics - Google Patents

Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics

Info

Publication number: AU2002365038A1
Authority: AU; Australia
Prior art keywords: antibiotics; inhibitors; alpha; identification; methods
Prior art date: 2001-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002365038A

Other versions

AU2002365038A8 (en

Inventor

Kiichi Adachi

Blaise Darveaux

Todd Dezwaan

Sheryl Frank

Lisbeth Hamer

Ryan Heiniger

Sze-Chung Lo

Sanjoy Mahanty

Maria Victoria Montenegro-Chamorro

Huaquin Pan

Jeffrey Shuster

Amy Skalchunes

Matthew Tanzer

Rex Tarpey

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cogenics Icoria Inc

Original Assignee

Paradigm Genetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-09

Filing date

2002-11-12

Publication date

2003-06-10

2001-11-09 Priority claimed from US10/011,200 external-priority patent/US6632631B1/en

2001-11-09 Priority claimed from US10/011,146 external-priority patent/US6723529B2/en

2002-11-12 Application filed by Paradigm Genetics Inc filed Critical Paradigm Genetics Inc

2003-06-10 Publication of AU2002365038A8 publication Critical patent/AU2002365038A8/en

2003-06-10 Publication of AU2002365038A1 publication Critical patent/AU2002365038A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01031—L-Aminoadipate-semialdehyde dehydrogenase (1.2.1.31), i.e. alpha-aminoadipate reductase

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Enzymes And Modification Thereof (AREA)

AU2002365038A 2001-11-09 2002-11-12 Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics Abandoned AU2002365038A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US10/011,200 US6632631B1 (en)	2001-11-09	2001-11-09	Methods for the identification of inhibitors of homocitrate synthase as antibiotics
US10/011,200		2001-11-09
US10/011,146 US6723529B2 (en)	2001-11-09	2001-11-09	Methods for the identification of inhibitors of α-aminoadipate reductase as antibiotics
US10/011,146		2001-11-09
PCT/US2002/036508 WO2003046130A2 (en)	2001-11-09	2002-11-12	Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics

Publications (2)

Publication Number	Publication Date
AU2002365038A8 AU2002365038A8 (en)	2003-06-10
AU2002365038A1 true AU2002365038A1 (en)	2003-06-10

Family

ID=26682060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002365038A Abandoned AU2002365038A1 (en)	2001-11-09	2002-11-12	Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics

Country Status (5)

Country	Link
EP (1)	EP1481080A4 (en)
JP (1)	JP2005510230A (en)
AU (1)	AU2002365038A1 (en)
CA (1)	CA2469772A1 (en)
WO (1)	WO2003046130A2 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6455248B1 (en) *	1996-05-20	2002-09-24	Miami University	Reagents and kits for detecting fungal pathogens in a biological sample

2002
- 2002-11-12 JP JP2003547565A patent/JP2005510230A/en active Pending
- 2002-11-12 CA CA002469772A patent/CA2469772A1/en not_active Abandoned
- 2002-11-12 EP EP02803979A patent/EP1481080A4/en not_active Withdrawn
- 2002-11-12 AU AU2002365038A patent/AU2002365038A1/en not_active Abandoned
- 2002-11-12 WO PCT/US2002/036508 patent/WO2003046130A2/en not_active Ceased

Also Published As

Publication number	Publication date
EP1481080A2 (en)	2004-12-01
WO2003046130A2 (en)	2003-06-05
AU2002365038A8 (en)	2003-06-10
CA2469772A1 (en)	2003-06-05
EP1481080A4 (en)	2006-02-22
WO2003046130A3 (en)	2004-09-16
JP2005510230A (en)	2005-04-21

Publication	Publication Date	Title
AU2002256418A1 (en)	2002-11-11	Inhibitors of bace
AU2002335090A1 (en)	2003-04-22	Methods and apparatuses for identification
PL359820A1 (en)	2004-09-06	Hmg-coa reductase inhibitors and method
AU2003259749A1 (en)	2004-02-25	3-pyrrolyl-pyridopyrazoles and 3-pyrrolyl-indazoles as novel kinase inhibitors
AU2002256085A1 (en)	2002-10-21	Quinoline inhibitors of hyak1 and hyak3 kinases
AU2001288360A1 (en)	2002-03-04	Genomics-assisted rapid identification of targets
AU2002337913A1 (en)	2003-04-28	Glycosulfopeptide inhibitors and methods of use thereof
AU2002219900A1 (en)	2002-06-11	Minimal identification of features
AU2002306734A1 (en)	2002-10-03	Inhibitors of plasmepsins
AU2002225465A1 (en)	2003-06-30	Method for determination of aluminum
AU2002214038A1 (en)	2002-05-15	Inhibitors of transglutaminases
AU2002303712A1 (en)	2002-11-25	Novel telomerase inhibitors and uses therefor
AUPR262801A0 (en)	2001-02-15	Method of blasting
AU2002365038A1 (en)	2003-06-10	Methods for the identification of inhibitors of alpha-aminoadipate reductase and homocitrate synthase as antibiotics
AU2002305868A1 (en)	2002-12-23	Inhibitors of reggamma
AU2003290258A1 (en)	2004-06-30	Method for identification and/or authentication of articles
AU2003299792A1 (en)	2004-09-28	Methods for the identification of inhibitors of pyrroline-5-carboxylate reductase as antibiotics
AU2002258749A1 (en)	2002-10-08	Inhibitors of glycosaminoglycans
AU2003290635A1 (en)	2004-06-03	Methods for the identification of trehalose-6-phosphate synthase as antibiotics
AU2002360614A1 (en)	2003-06-30	Methods of inhibiting fertility
HK1051044A (en)	2003-07-18	Hmg-coa reductase inhibitors and method
AU2002328906A1 (en)	2003-03-03	Inhibitors of polyq-aggregation
HK1080147A (en)	2006-04-21	Identification of kinase inhibitors
WO2002057987A8 (en)	2002-09-19	System and method for association of object sets
AU2001241889A1 (en)	2002-09-19	Method of identifying inhibitors of cdc25

Legal Events

Date	Code	Title	Description
2004-07-29	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase