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AU2002341195A1 - Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives - Google Patents

Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives

Info

Publication number
AU2002341195A1
AU2002341195A1 AU2002341195A AU2002341195A AU2002341195A1 AU 2002341195 A1 AU2002341195 A1 AU 2002341195A1 AU 2002341195 A AU2002341195 A AU 2002341195A AU 2002341195 A AU2002341195 A AU 2002341195A AU 2002341195 A1 AU2002341195 A1 AU 2002341195A1
Authority
AU
Australia
Prior art keywords
cyclohexane
pyridine
substituted
diamine derivatives
diamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002341195A
Other versions
AU2002341195B2 (en
Inventor
Helmut Buschmann
Barbara Heller
Corinna Maul
Bernd Sundermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10123163A external-priority patent/DE10123163A1/en
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2002341195A1 publication Critical patent/AU2002341195A1/en
Application granted granted Critical
Publication of AU2002341195B2 publication Critical patent/AU2002341195B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002341195A 2001-05-09 2002-05-08 Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives Ceased AU2002341195B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10123163A DE10123163A1 (en) 2001-05-09 2001-05-09 Substituted cyclohexane-1,4-diamine derivatives
DE10123163.6 2001-05-09
PCT/EP2002/005078 WO2002090330A1 (en) 2001-05-09 2002-05-08 Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives

Publications (2)

Publication Number Publication Date
AU2002341195A1 true AU2002341195A1 (en) 2003-05-01
AU2002341195B2 AU2002341195B2 (en) 2007-01-04

Family

ID=7684562

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2002341195A Ceased AU2002341195B2 (en) 2001-05-09 2002-05-08 Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives
AU2002312883A Ceased AU2002312883B2 (en) 2001-05-09 2002-05-08 Substituted cyclohexane-1,4-diamine derivatives
AU2007202033A Ceased AU2007202033B8 (en) 2001-05-09 2007-05-07 Substituted cyclohexane-1,4-diamine derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2002312883A Ceased AU2002312883B2 (en) 2001-05-09 2002-05-08 Substituted cyclohexane-1,4-diamine derivatives
AU2007202033A Ceased AU2007202033B8 (en) 2001-05-09 2007-05-07 Substituted cyclohexane-1,4-diamine derivatives

Country Status (30)

Country Link
US (3) US6998409B2 (en)
EP (3) EP1385825B1 (en)
JP (3) JP2004533439A (en)
KR (2) KR20040002943A (en)
CN (2) CN1533374B (en)
AR (1) AR035883A1 (en)
AT (2) ATE359260T1 (en)
AU (3) AU2002341195B2 (en)
BR (2) BR0209579A (en)
CA (3) CA2446461C (en)
CO (2) CO5700725A2 (en)
CY (2) CY1106468T1 (en)
CZ (2) CZ20032995A3 (en)
DE (3) DE10123163A1 (en)
DK (2) DK1392641T3 (en)
EC (2) ECSP034831A (en)
ES (2) ES2291486T3 (en)
HU (3) HU228253B1 (en)
IL (4) IL158784A0 (en)
MX (3) MXPA03010201A (en)
NO (2) NO326784B1 (en)
NZ (2) NZ529334A (en)
PE (1) PE20021094A1 (en)
PL (3) PL212887B1 (en)
PT (2) PT1385825E (en)
RU (2) RU2321579C2 (en)
SI (2) SI1385825T1 (en)
SK (2) SK286617B6 (en)
WO (3) WO2002090330A1 (en)
ZA (2) ZA200309522B (en)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10252650A1 (en) * 2002-11-11 2004-05-27 Grünenthal GmbH New 1,4-disubstituted cyclohexylamine derivatives, are opioid receptor like-receptor 1 receptor ligands useful e.g. for treating anxiety, depression, epilepsy, senile dementia, withdrawal symptoms or especially pain
DE10252665A1 (en) 2002-11-11 2004-06-03 Grünenthal GmbH 4-aminomethyl-1-aryl-cyclohexylamine derivatives
EP1560807B1 (en) 2002-11-12 2010-02-10 Grünenthal GmbH 4-hydroxymethyl-1-aryl-cyclohexylamine derivatives
BR0316397A (en) * 2002-11-19 2005-09-27 Achillion Pharmaceuticals Inc Substituted aryl thioureas and related compounds as viral replication inhibitors
US7354988B2 (en) 2003-08-12 2008-04-08 General Electric Company Electrically conductive compositions and method of manufacture thereof
US7026432B2 (en) 2003-08-12 2006-04-11 General Electric Company Electrically conductive compositions and method of manufacture thereof
US7378409B2 (en) * 2003-08-21 2008-05-27 Bristol-Myers Squibb Company Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
US7309727B2 (en) 2003-09-29 2007-12-18 General Electric Company Conductive thermoplastic compositions, methods of manufacture and articles derived from such compositions
DE10360792A1 (en) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclic cyclohexane derivatives
DE10360793A1 (en) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclic cyclohexane derivatives
DE102004023507A1 (en) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituted cyclohexylacetic acid derivatives
DE102004023522A1 (en) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituted cyclohexyl-1,4-diamine derivatives
DE102004023632A1 (en) 2004-05-10 2005-12-08 Grünenthal GmbH Substituted cyclohexylcarboxylic acid derivatives
DE102004023506A1 (en) * 2004-05-10 2005-12-01 Grünenthal GmbH Chain-extended substituted cyclohexyl-1,4-diamine derivatives
DE102004023508A1 (en) * 2004-05-10 2005-12-08 Grünenthal GmbH Acid derivatives of substituted cyclohexyl-1,4-diamine
DE102004023501A1 (en) * 2004-05-10 2005-12-01 Grünenthal GmbH Oxo-substituted cyclohexyl-1,4-diamine derivatives
DE102004023635A1 (en) 2004-05-10 2006-04-13 Grünenthal GmbH Heteroaryl-substituted cyclohexyl-1,4-diamine derivatives
TW200600492A (en) * 2004-05-18 2006-01-01 Achillion Pharmaceuticals Inc Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
US7462656B2 (en) 2005-02-15 2008-12-09 Sabic Innovative Plastics Ip B.V. Electrically conductive compositions and method of manufacture thereof
DE102005061428A1 (en) * 2005-12-22 2007-08-16 Grünenthal GmbH Substituted cyclohexylmethyl derivatives
DE102006033114A1 (en) 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclic azaindole derivatives
DE102006033109A1 (en) 2006-07-18 2008-01-31 Grünenthal GmbH Substituted heteroaryl derivatives
DE102006035787A1 (en) 2006-07-28 2008-03-13 Tesa Ag Process for punching non-tacky heat-activatable adhesives at room temperature
WO2008089307A2 (en) * 2007-01-18 2008-07-24 Lexicon Pharmaceuticals, Inc. Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer
CN101784274A (en) * 2007-06-15 2010-07-21 米申制药公司 Methods and compositions for inhibiting edema factor and adenylate cyclase
US20090215725A1 (en) * 2008-02-26 2009-08-27 Grunenthal Gmbh Substituted 4-aminocyclohexane derivatives
CN102046596B (en) * 2008-03-27 2013-12-25 格吕伦塔尔有限公司 Substituted cyclohexane diamines
AU2009228642B2 (en) 2008-03-27 2013-11-07 Grunenthal Gmbh Substituted 4-aminocyclohexane derivatives
ES2375543T3 (en) 2008-03-27 2012-03-01 Grünenthal GmbH DERIVATIVES OF ESPIRO (5.5) UNDECANO.
JP5650637B2 (en) 2008-03-27 2015-01-07 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング (Hetero-) aryl-cyclohexane derivatives
AU2009228647B2 (en) 2008-03-27 2013-07-04 Grunenthal Gmbh Substituted spirocyclic cyclohexane derivatives
RU2514192C2 (en) 2008-03-27 2014-04-27 Грюненталь Гмбх Hydroxymethyl cyclohexylamines
MY153948A (en) 2008-07-21 2015-04-15 Purdue Pharma Lp Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof
WO2010084160A1 (en) 2009-01-21 2010-07-29 Oryzon Genomics S.A. Phenylcyclopropylamine derivatives and their medical use
JP5699152B2 (en) 2009-09-25 2015-04-08 オリゾン・ジェノミックス・ソシエダッド・アノニマOryzon Genomics S.A. Lysine-specific demethylase-1 inhibitors and uses thereof
EP2486002B1 (en) 2009-10-09 2019-03-27 Oryzon Genomics, S.A. Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
WO2011106573A2 (en) 2010-02-24 2011-09-01 Oryzon Genomics, S.A. Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
WO2011106105A2 (en) 2010-02-24 2011-09-01 Oryzon Genomics, S.A. Inhibitors for antiviral use
DK2560947T3 (en) 2010-04-19 2016-11-21 Oryzon Genomics Sa LYSINE-SPECIFIC demethylase-1 INHIBITORS AND THEIR USE
RU2611437C2 (en) 2010-07-29 2017-02-22 Оризон Дженомикс С.А. Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use
WO2012013727A1 (en) 2010-07-29 2012-02-02 Oryzon Genomics S.A. Cyclopropylamine derivatives useful as lsd1 inhibitors
US9061966B2 (en) 2010-10-08 2015-06-23 Oryzon Genomics S.A. Cyclopropylamine inhibitors of oxidases
WO2012072713A2 (en) 2010-11-30 2012-06-07 Oryzon Genomics, S.A. Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
EP3981395A1 (en) 2011-02-08 2022-04-13 Oryzon Genomics, S.A. Lysine demethylase inhibitors for myeloproliferative disorders
EP3736265A1 (en) 2011-10-20 2020-11-11 Oryzon Genomics, S.A. (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors
IN2014CN03337A (en) 2011-10-20 2015-07-03 Oryzon Genomics Sa
TWI773657B (en) 2015-12-18 2022-08-11 美商亞德利克斯公司 Substituted 4-phenyl pyridine compounds as non-systemic tgr5 agonists
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172460B (en) * 1975-10-03 1978-09-28 Chinoin Gyogyszer Es Vegyeszet SPOSOB POLUCHENIA NOVYKH PROIZVODNYKH 5,6-DIGIDRO-3H-PIRIMIDIN-4-ONA
US4065573A (en) * 1976-06-03 1977-12-27 The Upjohn Company 4-Amino-4-phenylcyclohexanone ketal compositions and process of use
US4113866A (en) * 1977-04-01 1978-09-12 The Upjohn Company Analgetic compounds, compositions and process of treatment
US4447454A (en) * 1977-04-01 1984-05-08 The Upjohn Company Analgetic compounds, compositions and process of treatment
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US4906655A (en) 1989-01-24 1990-03-06 Warner-Lambert Company Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents
US5153226A (en) 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
EP0524439A1 (en) * 1991-07-24 1993-01-27 F.Hoffmann-La Roche & Co. Aktiengesellschaft Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives
FR2687147A1 (en) 1992-02-11 1993-08-13 Union Pharma Scient Appl NOVEL ALPHA-AMINO N-PYRIDYL BENZENE PROPANAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
US5620955A (en) 1993-06-18 1997-04-15 Peptide Technologies Corporation Bombesin receptor antagonists and uses thereof
GB9411099D0 (en) * 1994-06-03 1994-07-27 Wyeth John & Brother Ltd Piperazine derivatives
US5565568A (en) 1995-04-06 1996-10-15 Eli Lilly And Company 2-acylaminopropanamides as tachykinin receptor antagonists
AU6772996A (en) 1995-08-21 1997-03-12 Eli Lilly And Company 2-acylaminopropanamides as growth hormone secretagogues
ES2253782T3 (en) 1996-08-22 2006-06-01 Warner-Lambert Company Llc NON-PEPTIDIC BOMBESINE RECEIVER ANTAGONISTS.
US6423725B1 (en) * 1998-01-19 2002-07-23 Pfizer Inc 4-(2-keto-1-benzimidazolinyl)piperidine compounds as ORL1-receptor agonists
US20020169101A1 (en) 1999-05-10 2002-11-14 Gonzalez Maria Isabel Treatment of sexual dysfunction
GB0006289D0 (en) 2000-03-15 2000-05-03 Smithkline Beecham Plc New use
GB0012240D0 (en) * 2000-05-19 2000-07-12 Merck Sharp & Dohme Therapeutic agents
US20020028799A1 (en) 2000-07-06 2002-03-07 Naylor Alasdair Mark Treatment of male sexual dysfunction
US6991916B2 (en) 2000-07-14 2006-01-31 Pfizer Inc. Compounds for the treatment of sexual dysfunction
DE60135764D1 (en) * 2000-10-06 2008-10-23 Mitsubishi Tanabe Pharma Corp NITROGENIC, FIVE-GLASS RING COMPOUNDS
AU2002237706A1 (en) 2000-11-06 2002-05-27 Terry Y. Shibuya Bioactive surgical suture
US20040039198A1 (en) 2000-11-16 2004-02-26 Bender Paul E. Compounds
GB2369117A (en) 2000-11-17 2002-05-22 Warner Lambert Co Bombesin receptor antagonists
GB2369118A (en) 2000-11-17 2002-05-22 Warner Lambert Co Bombesin receptor antagonists
BR0115364A (en) 2000-11-17 2003-09-23 Warner Lambert Co Treatment of sexual dysfunction
MXPA03003482A (en) 2000-11-17 2004-09-10 Warner Lambert Co Treatment of sexual dysfunction.
IL155814A0 (en) 2000-11-17 2003-12-23 Warner Lambert Co Treatment of sexual dysfunction using bombesin antagonist
US20030119714A1 (en) 2000-12-15 2003-06-26 Naylor Alasdair Mark Treatment of male sexual dysfunction

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