AU2002341195A1 - Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives - Google Patents
Substituted 2-pyridine-cyclohexane-1,4-diamine derivativesInfo
- Publication number
- AU2002341195A1 AU2002341195A1 AU2002341195A AU2002341195A AU2002341195A1 AU 2002341195 A1 AU2002341195 A1 AU 2002341195A1 AU 2002341195 A AU2002341195 A AU 2002341195A AU 2002341195 A AU2002341195 A AU 2002341195A AU 2002341195 A1 AU2002341195 A1 AU 2002341195A1
- Authority
- AU
- Australia
- Prior art keywords
- cyclohexane
- pyridine
- substituted
- diamine derivatives
- diamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123163A DE10123163A1 (en) | 2001-05-09 | 2001-05-09 | Substituted cyclohexane-1,4-diamine derivatives |
| DE10123163.6 | 2001-05-09 | ||
| PCT/EP2002/005078 WO2002090330A1 (en) | 2001-05-09 | 2002-05-08 | Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002341195A1 true AU2002341195A1 (en) | 2003-05-01 |
| AU2002341195B2 AU2002341195B2 (en) | 2007-01-04 |
Family
ID=7684562
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002341195A Ceased AU2002341195B2 (en) | 2001-05-09 | 2002-05-08 | Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives |
| AU2002312883A Ceased AU2002312883B2 (en) | 2001-05-09 | 2002-05-08 | Substituted cyclohexane-1,4-diamine derivatives |
| AU2007202033A Ceased AU2007202033B8 (en) | 2001-05-09 | 2007-05-07 | Substituted cyclohexane-1,4-diamine derivatives |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002312883A Ceased AU2002312883B2 (en) | 2001-05-09 | 2002-05-08 | Substituted cyclohexane-1,4-diamine derivatives |
| AU2007202033A Ceased AU2007202033B8 (en) | 2001-05-09 | 2007-05-07 | Substituted cyclohexane-1,4-diamine derivatives |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US6998409B2 (en) |
| EP (3) | EP1385825B1 (en) |
| JP (3) | JP2004533439A (en) |
| KR (2) | KR20040002943A (en) |
| CN (2) | CN1533374B (en) |
| AR (1) | AR035883A1 (en) |
| AT (2) | ATE359260T1 (en) |
| AU (3) | AU2002341195B2 (en) |
| BR (2) | BR0209579A (en) |
| CA (3) | CA2446461C (en) |
| CO (2) | CO5700725A2 (en) |
| CY (2) | CY1106468T1 (en) |
| CZ (2) | CZ20032995A3 (en) |
| DE (3) | DE10123163A1 (en) |
| DK (2) | DK1392641T3 (en) |
| EC (2) | ECSP034831A (en) |
| ES (2) | ES2291486T3 (en) |
| HU (3) | HU228253B1 (en) |
| IL (4) | IL158784A0 (en) |
| MX (3) | MXPA03010201A (en) |
| NO (2) | NO326784B1 (en) |
| NZ (2) | NZ529334A (en) |
| PE (1) | PE20021094A1 (en) |
| PL (3) | PL212887B1 (en) |
| PT (2) | PT1385825E (en) |
| RU (2) | RU2321579C2 (en) |
| SI (2) | SI1385825T1 (en) |
| SK (2) | SK286617B6 (en) |
| WO (3) | WO2002090330A1 (en) |
| ZA (2) | ZA200309522B (en) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10252650A1 (en) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | New 1,4-disubstituted cyclohexylamine derivatives, are opioid receptor like-receptor 1 receptor ligands useful e.g. for treating anxiety, depression, epilepsy, senile dementia, withdrawal symptoms or especially pain |
| DE10252665A1 (en) | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-aminomethyl-1-aryl-cyclohexylamine derivatives |
| EP1560807B1 (en) | 2002-11-12 | 2010-02-10 | Grünenthal GmbH | 4-hydroxymethyl-1-aryl-cyclohexylamine derivatives |
| BR0316397A (en) * | 2002-11-19 | 2005-09-27 | Achillion Pharmaceuticals Inc | Substituted aryl thioureas and related compounds as viral replication inhibitors |
| US7354988B2 (en) | 2003-08-12 | 2008-04-08 | General Electric Company | Electrically conductive compositions and method of manufacture thereof |
| US7026432B2 (en) | 2003-08-12 | 2006-04-11 | General Electric Company | Electrically conductive compositions and method of manufacture thereof |
| US7378409B2 (en) * | 2003-08-21 | 2008-05-27 | Bristol-Myers Squibb Company | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity |
| US7309727B2 (en) | 2003-09-29 | 2007-12-18 | General Electric Company | Conductive thermoplastic compositions, methods of manufacture and articles derived from such compositions |
| DE10360792A1 (en) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclic cyclohexane derivatives |
| DE10360793A1 (en) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclic cyclohexane derivatives |
| DE102004023507A1 (en) * | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Substituted cyclohexylacetic acid derivatives |
| DE102004023522A1 (en) * | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Substituted cyclohexyl-1,4-diamine derivatives |
| DE102004023632A1 (en) | 2004-05-10 | 2005-12-08 | Grünenthal GmbH | Substituted cyclohexylcarboxylic acid derivatives |
| DE102004023506A1 (en) * | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Chain-extended substituted cyclohexyl-1,4-diamine derivatives |
| DE102004023508A1 (en) * | 2004-05-10 | 2005-12-08 | Grünenthal GmbH | Acid derivatives of substituted cyclohexyl-1,4-diamine |
| DE102004023501A1 (en) * | 2004-05-10 | 2005-12-01 | Grünenthal GmbH | Oxo-substituted cyclohexyl-1,4-diamine derivatives |
| DE102004023635A1 (en) | 2004-05-10 | 2006-04-13 | Grünenthal GmbH | Heteroaryl-substituted cyclohexyl-1,4-diamine derivatives |
| TW200600492A (en) * | 2004-05-18 | 2006-01-01 | Achillion Pharmaceuticals Inc | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
| US7462656B2 (en) | 2005-02-15 | 2008-12-09 | Sabic Innovative Plastics Ip B.V. | Electrically conductive compositions and method of manufacture thereof |
| DE102005061428A1 (en) * | 2005-12-22 | 2007-08-16 | Grünenthal GmbH | Substituted cyclohexylmethyl derivatives |
| DE102006033114A1 (en) | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclic azaindole derivatives |
| DE102006033109A1 (en) | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituted heteroaryl derivatives |
| DE102006035787A1 (en) | 2006-07-28 | 2008-03-13 | Tesa Ag | Process for punching non-tacky heat-activatable adhesives at room temperature |
| WO2008089307A2 (en) * | 2007-01-18 | 2008-07-24 | Lexicon Pharmaceuticals, Inc. | Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer |
| CN101784274A (en) * | 2007-06-15 | 2010-07-21 | 米申制药公司 | Methods and compositions for inhibiting edema factor and adenylate cyclase |
| US20090215725A1 (en) * | 2008-02-26 | 2009-08-27 | Grunenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| CN102046596B (en) * | 2008-03-27 | 2013-12-25 | 格吕伦塔尔有限公司 | Substituted cyclohexane diamines |
| AU2009228642B2 (en) | 2008-03-27 | 2013-11-07 | Grunenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| ES2375543T3 (en) | 2008-03-27 | 2012-03-01 | Grünenthal GmbH | DERIVATIVES OF ESPIRO (5.5) UNDECANO. |
| JP5650637B2 (en) | 2008-03-27 | 2015-01-07 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | (Hetero-) aryl-cyclohexane derivatives |
| AU2009228647B2 (en) | 2008-03-27 | 2013-07-04 | Grunenthal Gmbh | Substituted spirocyclic cyclohexane derivatives |
| RU2514192C2 (en) | 2008-03-27 | 2014-04-27 | Грюненталь Гмбх | Hydroxymethyl cyclohexylamines |
| MY153948A (en) | 2008-07-21 | 2015-04-15 | Purdue Pharma Lp | Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof |
| WO2010084160A1 (en) | 2009-01-21 | 2010-07-29 | Oryzon Genomics S.A. | Phenylcyclopropylamine derivatives and their medical use |
| JP5699152B2 (en) | 2009-09-25 | 2015-04-08 | オリゾン・ジェノミックス・ソシエダッド・アノニマOryzon Genomics S.A. | Lysine-specific demethylase-1 inhibitors and uses thereof |
| EP2486002B1 (en) | 2009-10-09 | 2019-03-27 | Oryzon Genomics, S.A. | Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use |
| WO2011106573A2 (en) | 2010-02-24 | 2011-09-01 | Oryzon Genomics, S.A. | Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae |
| WO2011106105A2 (en) | 2010-02-24 | 2011-09-01 | Oryzon Genomics, S.A. | Inhibitors for antiviral use |
| DK2560947T3 (en) | 2010-04-19 | 2016-11-21 | Oryzon Genomics Sa | LYSINE-SPECIFIC demethylase-1 INHIBITORS AND THEIR USE |
| RU2611437C2 (en) | 2010-07-29 | 2017-02-22 | Оризон Дженомикс С.А. | Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use |
| WO2012013727A1 (en) | 2010-07-29 | 2012-02-02 | Oryzon Genomics S.A. | Cyclopropylamine derivatives useful as lsd1 inhibitors |
| US9061966B2 (en) | 2010-10-08 | 2015-06-23 | Oryzon Genomics S.A. | Cyclopropylamine inhibitors of oxidases |
| WO2012072713A2 (en) | 2010-11-30 | 2012-06-07 | Oryzon Genomics, S.A. | Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae |
| EP3981395A1 (en) | 2011-02-08 | 2022-04-13 | Oryzon Genomics, S.A. | Lysine demethylase inhibitors for myeloproliferative disorders |
| EP3736265A1 (en) | 2011-10-20 | 2020-11-11 | Oryzon Genomics, S.A. | (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors |
| IN2014CN03337A (en) | 2011-10-20 | 2015-07-03 | Oryzon Genomics Sa | |
| TWI773657B (en) | 2015-12-18 | 2022-08-11 | 美商亞德利克斯公司 | Substituted 4-phenyl pyridine compounds as non-systemic tgr5 agonists |
| US12084472B2 (en) | 2015-12-18 | 2024-09-10 | Ardelyx, Inc. | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU172460B (en) * | 1975-10-03 | 1978-09-28 | Chinoin Gyogyszer Es Vegyeszet | SPOSOB POLUCHENIA NOVYKH PROIZVODNYKH 5,6-DIGIDRO-3H-PIRIMIDIN-4-ONA |
| US4065573A (en) * | 1976-06-03 | 1977-12-27 | The Upjohn Company | 4-Amino-4-phenylcyclohexanone ketal compositions and process of use |
| US4113866A (en) * | 1977-04-01 | 1978-09-12 | The Upjohn Company | Analgetic compounds, compositions and process of treatment |
| US4447454A (en) * | 1977-04-01 | 1984-05-08 | The Upjohn Company | Analgetic compounds, compositions and process of treatment |
| US5877277A (en) | 1987-09-24 | 1999-03-02 | Biomeasure, Inc. | Octapeptide bombesin analogs |
| US4906655A (en) | 1989-01-24 | 1990-03-06 | Warner-Lambert Company | Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents |
| US5153226A (en) | 1989-08-31 | 1992-10-06 | Warner-Lambert Company | Acat inhibitors for treating hypocholesterolemia |
| EP0524439A1 (en) * | 1991-07-24 | 1993-01-27 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives |
| FR2687147A1 (en) | 1992-02-11 | 1993-08-13 | Union Pharma Scient Appl | NOVEL ALPHA-AMINO N-PYRIDYL BENZENE PROPANAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| US5620955A (en) | 1993-06-18 | 1997-04-15 | Peptide Technologies Corporation | Bombesin receptor antagonists and uses thereof |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
| US5565568A (en) | 1995-04-06 | 1996-10-15 | Eli Lilly And Company | 2-acylaminopropanamides as tachykinin receptor antagonists |
| AU6772996A (en) | 1995-08-21 | 1997-03-12 | Eli Lilly And Company | 2-acylaminopropanamides as growth hormone secretagogues |
| ES2253782T3 (en) | 1996-08-22 | 2006-06-01 | Warner-Lambert Company Llc | NON-PEPTIDIC BOMBESINE RECEIVER ANTAGONISTS. |
| US6423725B1 (en) * | 1998-01-19 | 2002-07-23 | Pfizer Inc | 4-(2-keto-1-benzimidazolinyl)piperidine compounds as ORL1-receptor agonists |
| US20020169101A1 (en) | 1999-05-10 | 2002-11-14 | Gonzalez Maria Isabel | Treatment of sexual dysfunction |
| GB0006289D0 (en) | 2000-03-15 | 2000-05-03 | Smithkline Beecham Plc | New use |
| GB0012240D0 (en) * | 2000-05-19 | 2000-07-12 | Merck Sharp & Dohme | Therapeutic agents |
| US20020028799A1 (en) | 2000-07-06 | 2002-03-07 | Naylor Alasdair Mark | Treatment of male sexual dysfunction |
| US6991916B2 (en) | 2000-07-14 | 2006-01-31 | Pfizer Inc. | Compounds for the treatment of sexual dysfunction |
| DE60135764D1 (en) * | 2000-10-06 | 2008-10-23 | Mitsubishi Tanabe Pharma Corp | NITROGENIC, FIVE-GLASS RING COMPOUNDS |
| AU2002237706A1 (en) | 2000-11-06 | 2002-05-27 | Terry Y. Shibuya | Bioactive surgical suture |
| US20040039198A1 (en) | 2000-11-16 | 2004-02-26 | Bender Paul E. | Compounds |
| GB2369117A (en) | 2000-11-17 | 2002-05-22 | Warner Lambert Co | Bombesin receptor antagonists |
| GB2369118A (en) | 2000-11-17 | 2002-05-22 | Warner Lambert Co | Bombesin receptor antagonists |
| BR0115364A (en) | 2000-11-17 | 2003-09-23 | Warner Lambert Co | Treatment of sexual dysfunction |
| MXPA03003482A (en) | 2000-11-17 | 2004-09-10 | Warner Lambert Co | Treatment of sexual dysfunction. |
| IL155814A0 (en) | 2000-11-17 | 2003-12-23 | Warner Lambert Co | Treatment of sexual dysfunction using bombesin antagonist |
| US20030119714A1 (en) | 2000-12-15 | 2003-06-26 | Naylor Alasdair Mark | Treatment of male sexual dysfunction |
-
2001
- 2001-05-09 DE DE10123163A patent/DE10123163A1/en not_active Withdrawn
-
2002
- 2002-05-08 NZ NZ529334A patent/NZ529334A/en not_active IP Right Cessation
- 2002-05-08 SK SK1378-2003A patent/SK286617B6/en not_active IP Right Cessation
- 2002-05-08 KR KR10-2003-7014530A patent/KR20040002943A/en not_active Ceased
- 2002-05-08 ES ES02750900T patent/ES2291486T3/en not_active Expired - Lifetime
- 2002-05-08 CZ CZ20032995A patent/CZ20032995A3/en unknown
- 2002-05-08 IL IL15878402A patent/IL158784A0/en unknown
- 2002-05-08 RU RU2003134147/04A patent/RU2321579C2/en not_active IP Right Cessation
- 2002-05-08 CA CA2446461A patent/CA2446461C/en not_active Expired - Fee Related
- 2002-05-08 PL PL368851A patent/PL212887B1/en unknown
- 2002-05-08 SI SI200230627T patent/SI1385825T1/en unknown
- 2002-05-08 AU AU2002341195A patent/AU2002341195B2/en not_active Ceased
- 2002-05-08 BR BR0209579-3A patent/BR0209579A/en active Search and Examination
- 2002-05-08 EP EP02750900A patent/EP1385825B1/en not_active Expired - Lifetime
- 2002-05-08 CN CN028137531A patent/CN1533374B/en not_active Expired - Fee Related
- 2002-05-08 HU HU0400888A patent/HU228253B1/en not_active IP Right Cessation
- 2002-05-08 SI SI200230571T patent/SI1392641T1/en unknown
- 2002-05-08 EP EP02738038A patent/EP1392641B1/en not_active Expired - Lifetime
- 2002-05-08 WO PCT/EP2002/005078 patent/WO2002090330A1/en not_active Ceased
- 2002-05-08 JP JP2002587399A patent/JP2004533439A/en active Pending
- 2002-05-08 BR BR0209580-7A patent/BR0209580A/en not_active Application Discontinuation
- 2002-05-08 DE DE50210707T patent/DE50210707D1/en not_active Expired - Lifetime
- 2002-05-08 MX MXPA03010201A patent/MXPA03010201A/en active IP Right Grant
- 2002-05-08 HU HU0400989A patent/HU229288B1/en not_active IP Right Cessation
- 2002-05-08 DK DK02738038T patent/DK1392641T3/en active
- 2002-05-08 MX MXPA03010134A patent/MXPA03010134A/en active IP Right Grant
- 2002-05-08 WO PCT/EP2002/005051 patent/WO2002090317A1/en not_active Ceased
- 2002-05-08 RU RU2003134145/04A patent/RU2287523C2/en not_active IP Right Cessation
- 2002-05-08 DE DE50209929T patent/DE50209929D1/en not_active Expired - Lifetime
- 2002-05-08 IL IL15878202A patent/IL158782A0/en unknown
- 2002-05-08 AT AT02738038T patent/ATE359260T1/en active
- 2002-05-08 AU AU2002312883A patent/AU2002312883B2/en not_active Ceased
- 2002-05-08 JP JP2002587410A patent/JP2004528374A/en active Pending
- 2002-05-08 CZ CZ20033005A patent/CZ20033005A3/en unknown
- 2002-05-08 DK DK02750900T patent/DK1385825T3/en active
- 2002-05-08 AT AT02750900T patent/ATE370120T1/en active
- 2002-05-08 CA CA2446463A patent/CA2446463C/en not_active Expired - Fee Related
- 2002-05-08 PT PT02750900T patent/PT1385825E/en unknown
- 2002-05-08 CN CNB028135571A patent/CN1307158C/en not_active Expired - Fee Related
- 2002-05-08 PL PL366662A patent/PL220595B1/en unknown
- 2002-05-08 NZ NZ529147A patent/NZ529147A/en not_active IP Right Cessation
- 2002-05-08 ES ES02738038T patent/ES2284876T3/en not_active Expired - Lifetime
- 2002-05-08 KR KR1020037014568A patent/KR100895778B1/en not_active Expired - Fee Related
- 2002-05-08 PT PT02738038T patent/PT1392641E/en unknown
- 2002-05-08 SK SK1379-2003A patent/SK287319B6/en not_active IP Right Cessation
- 2002-05-09 JP JP2002586920A patent/JP2005515959A/en not_active Withdrawn
- 2002-05-09 PE PE2002000388A patent/PE20021094A1/en not_active Application Discontinuation
- 2002-05-09 HU HU0400963A patent/HUP0400963A2/en unknown
- 2002-05-09 EP EP02769145A patent/EP1385493A1/en not_active Withdrawn
- 2002-05-09 WO PCT/EP2002/005122 patent/WO2002089783A1/en not_active Ceased
- 2002-05-09 CA CA002446735A patent/CA2446735A1/en not_active Abandoned
- 2002-05-09 PL PL02366631A patent/PL366631A1/en not_active Application Discontinuation
- 2002-05-09 MX MXPA03010195A patent/MXPA03010195A/en unknown
- 2002-05-10 AR ARP020101704A patent/AR035883A1/en unknown
-
2003
- 2003-11-05 NO NO20034931A patent/NO326784B1/en not_active IP Right Cessation
- 2003-11-05 NO NO20034930A patent/NO328600B1/en not_active IP Right Cessation
- 2003-11-06 IL IL158784A patent/IL158784A/en not_active IP Right Cessation
- 2003-11-06 IL IL158782A patent/IL158782A/en not_active IP Right Cessation
- 2003-11-07 CO CO03098857A patent/CO5700725A2/en not_active Application Discontinuation
- 2003-11-07 EC EC2003004831A patent/ECSP034831A/en unknown
- 2003-11-07 CO CO03098846A patent/CO5540300A2/en active IP Right Grant
- 2003-11-07 EC EC2003004830A patent/ECSP034830A/en unknown
- 2003-11-10 US US10/704,200 patent/US6998409B2/en not_active Expired - Fee Related
- 2003-11-10 US US10/704,329 patent/US7276518B2/en not_active Expired - Fee Related
- 2003-11-10 US US10/704,524 patent/US20040229872A1/en not_active Abandoned
- 2003-12-08 ZA ZA2003/09522A patent/ZA200309522B/en unknown
- 2003-12-08 ZA ZA200309521A patent/ZA200309521B/en unknown
-
2007
- 2007-05-07 AU AU2007202033A patent/AU2007202033B8/en not_active Ceased
- 2007-05-10 CY CY20071100630T patent/CY1106468T1/en unknown
- 2007-10-25 CY CY20071101374T patent/CY1108067T1/en unknown
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