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AU2002238947A1 - Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient - Google Patents

Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient

Info

Publication number
AU2002238947A1
AU2002238947A1 AU2002238947A AU2002238947A AU2002238947A1 AU 2002238947 A1 AU2002238947 A1 AU 2002238947A1 AU 2002238947 A AU2002238947 A AU 2002238947A AU 2002238947 A AU2002238947 A AU 2002238947A AU 2002238947 A1 AU2002238947 A1 AU 2002238947A1
Authority
AU
Australia
Prior art keywords
triazaspiro
same
active ingredient
drugs containing
undecane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002238947A
Other versions
AU2002238947B2 (en
Inventor
Hiromu Habashita
Shin-Ichi Hamano
Shiro Shibayama
Yoshikazu Takaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority claimed from PCT/JP2002/002554 external-priority patent/WO2002074770A1/en
Publication of AU2002238947A1 publication Critical patent/AU2002238947A1/en
Application granted granted Critical
Publication of AU2002238947B2 publication Critical patent/AU2002238947B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002238947A 2001-03-19 2002-03-18 Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient Ceased AU2002238947B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2001079610 2001-03-19
JP2001-79610 2001-03-19
JP2001-160251 2001-05-29
JP2001160251 2001-05-29
PCT/JP2002/002554 WO2002074770A1 (en) 2001-03-19 2002-03-18 Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient

Publications (2)

Publication Number Publication Date
AU2002238947A1 true AU2002238947A1 (en) 2003-03-27
AU2002238947B2 AU2002238947B2 (en) 2007-10-18

Family

ID=26611613

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002238947A Ceased AU2002238947B2 (en) 2001-03-19 2002-03-18 Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient

Country Status (23)

Country Link
US (2) US7053090B2 (en)
EP (2) EP1378510B1 (en)
JP (1) JP3558079B2 (en)
KR (1) KR100714154B1 (en)
CN (1) CN1291988C (en)
AT (1) ATE328884T1 (en)
AU (1) AU2002238947B2 (en)
BR (1) BR0208167A (en)
CA (1) CA2440264A1 (en)
CZ (1) CZ20032531A3 (en)
DE (1) DE60212110T2 (en)
DK (1) DK1378510T3 (en)
ES (1) ES2266452T3 (en)
HU (1) HUP0400229A2 (en)
IL (1) IL157819A0 (en)
MX (1) MXPA03008529A (en)
NO (1) NO20034148L (en)
NZ (1) NZ528249A (en)
PL (1) PL364427A1 (en)
PT (1) PT1378510E (en)
RU (1) RU2269528C2 (en)
TW (1) TWI254047B (en)
WO (1) WO2002074770A1 (en)

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KR20030093248A (en) * 2001-03-19 2003-12-06 오노 야꾸힝 고교 가부시키가이샤 Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient
PL376154A1 (en) * 2002-09-18 2005-12-27 Ono Pharmaceutical Co, Ltd. Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
US7361758B2 (en) * 2002-09-18 2008-04-22 Ono Pharmaceutical Co., Ltd. Crystals of triazaspiro[5.5]undecane derivative
JP2006514646A (en) 2002-12-13 2006-05-11 スミスクライン ビーチャム コーポレーション Cyclohexyl compounds as CCR5 antagonists
DE60322423D1 (en) * 2002-12-13 2008-09-04 Smithkline Beecham Corp PYRROLIDIN AND AZETIDIN COMPOUNDS ALSCCR5 ANTAGONISTS
JPWO2004054616A1 (en) * 2002-12-13 2006-04-20 小野薬品工業株式会社 Antagonists and agonists that bind to strong binding sites of chemokine receptors
WO2004080966A1 (en) 2003-03-14 2004-09-23 Ono Pharmaceutical Co., Ltd. Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
WO2004092169A1 (en) * 2003-04-18 2004-10-28 Ono Pharmaceutical Co., Ltd. Spiropiperidine compound and medicinal use thereof
JPWO2004094424A1 (en) * 2003-04-21 2006-07-13 小野薬品工業株式会社 Nitrogen-containing heterocyclic compounds and uses thereof
JPWO2004098638A1 (en) * 2003-05-06 2006-07-13 小野薬品工業株式会社 Effector cell function inhibitor
EP1790639B1 (en) 2004-08-27 2014-03-26 Ono Pharmaceutical Co., Ltd. Spirocyclic compounds and their use as cxcr4-antagonists
PE20090123A1 (en) 2004-09-13 2009-03-10 Ono Pharmaceutical Co A HETEROCYCLIC DERIVATIVE CONTAINING NITROGEN AND A DRUG CONTAINING THE SAME AS THE ACTIVE INGREDIENT
JP5272408B2 (en) 2005-02-25 2013-08-28 小野薬品工業株式会社 Nitrogen-containing heterocyclic compound and pharmaceutical use thereof
EP1874755A4 (en) 2005-04-20 2010-04-28 Merck Sharp & Dohme BENZOTHIOPHENE DERIVATIVES OF HYDROXAMIC ACID
CA2605110A1 (en) 2005-04-20 2006-11-02 Merck & Co., Inc. Benzothiophene derivatives
JP2008536924A (en) 2005-04-20 2008-09-11 メルク エンド カムパニー インコーポレーテッド Carbamate, urea, amide and sulfonamide substituted derivatives of benzothiophene hydroxamic acid
WO2006129679A1 (en) 2005-05-31 2006-12-07 Ono Pharmaceutical Co., Ltd. Spiropiperidine compound and medicinal use thereof
EP1896395B1 (en) 2005-06-24 2015-07-15 Merck Sharp & Dohme Corp. Modified malonate derivatives
ES2407115T3 (en) 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compound containing a basic group and its use
AR057579A1 (en) * 2005-11-23 2007-12-05 Merck & Co Inc SPIROCICLICAL COMPOUNDS AS INHIBITORS OF ACETYLASE HISTONE (HDAC)
AU2007221207A1 (en) 2006-02-28 2007-09-07 Merck Sharp & Dohme Corp. Inhibitors of histone deacetylase
CA2644368A1 (en) 2006-03-10 2007-09-20 Ono Pharmaceutical Co., Ltd. Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
AU2007243519A1 (en) 2006-04-26 2007-11-08 Merck Sharp & Dohme Corp. Disubstituted aniline compounds
EP2042503B1 (en) 2006-05-16 2013-01-30 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
US8119652B2 (en) 2006-05-18 2012-02-21 Merck Sharp & Dohme Corp. Aryl-fused spirocyclic compounds
US7981874B2 (en) 2006-07-20 2011-07-19 Merck Sharp & Dohme Corp. Phosphorus derivatives as histone deacetylase inhibitors
RU2320660C1 (en) * 2007-01-31 2008-03-27 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" 1-AROYLOXY-4-HYDROXY-3-OXO-1,2,3,4,4a,5,6,7,8,8a-DECAHYDROQUINOXALIN-2-SPIRO(1-o-HYDROXYPHENYL-4,5-DIOXO-2,3,4,5-TETRAHYDROPYRROLES) AND METHOD FOR THEIR PREPARING
EP3103791B1 (en) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
WO2009005638A2 (en) 2007-06-27 2009-01-08 Merck & Co., Inc. Pyridyl and pyrimidinyl derivatives as histone deacetylase inhibitors
WO2010009196A1 (en) * 2008-07-15 2010-01-21 Temple University Of The Commonwealth System Of Higher Education Synthesis of bis-peptides oligomers comprising at least one n-substituted diketopiperazine as structural moiety
RU2387651C1 (en) * 2008-12-18 2010-04-27 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" Ethyl 1'-benzyl-3,3-dimetnyl-1,2'-dioxo-5'-phenyl-1'2,2',3,4,10-hexahydro-1h-spiro[acridine-9,3'-pyrrol]-4'-carboxylates and synthesis method thereof
RU2455284C1 (en) * 2011-03-15 2012-07-10 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" Method of producing 5-aryl-2-methyl-1,3-dioxo-2-azaspiro[5,5] undecane-4-carbonitriles and agent exhibiting analgesic activity
KR102030127B1 (en) * 2019-01-10 2019-10-08 주식회사 보타닉센스 Composition including undecane or undecanal as active ingredients for anti-allergy, improvement of atopic dermatitis, or skin regeneration
TW202110844A (en) * 2019-06-04 2021-03-16 日商第一三共股份有限公司 Dispiro-diketopiperazine compounds
RU2752079C1 (en) * 2020-12-01 2021-07-22 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (e)-(6-(2-hydroxyphenyl)-2-iminio-4,7,8-trioxo-1,3-diphenyl-1,3,6-triazaspiro[4.4]nonan-9-ylidene)(4-methoxyphenyl)methanoate with antimicrobial activity and its preparation method
CN119139317B (en) * 2024-11-19 2025-03-28 中国科学院杭州医学研究所 Application of compound in preparation of medicines for treating allergic rhinitis

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AT349470B (en) * 1975-02-28 1979-04-10 Yoshitomi Pharmaceutical PROCESS FOR THE PREPARATION OF NEW 4,4-DIPHENYLCYCLOHEXYLPIPERIDINE DERIVATIVES AND THEIR PHARMACEUTICAL ACID ADDITION SALTS
CA2233204A1 (en) * 1995-09-29 1997-04-03 Joseph A. Jakubowski Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation
WO1998025605A1 (en) * 1996-12-13 1998-06-18 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
WO1998031364A1 (en) * 1997-01-21 1998-07-23 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
US6288083B1 (en) * 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
RU2265021C2 (en) * 1999-12-03 2005-11-27 Оно Фармасьютикал Ко., Лтд. Derivatives of triazaspiro[5,5]undecane (variants), pharmaceutical composition and method for control of chemokine/chemokine receptor
TWI224597B (en) * 1999-12-03 2004-12-01 Ono Pharmaceutical Co Triazaspiro[5.5]undecane derivatives and a medicine containing the derivatives as an active ingredient
KR20030093248A (en) 2001-03-19 2003-12-06 오노 야꾸힝 고교 가부시키가이샤 Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient

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