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AU2002232521A1 - Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging - Google Patents

Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging

Info

Publication number
AU2002232521A1
AU2002232521A1 AU2002232521A AU3252102A AU2002232521A1 AU 2002232521 A1 AU2002232521 A1 AU 2002232521A1 AU 2002232521 A AU2002232521 A AU 2002232521A AU 3252102 A AU3252102 A AU 3252102A AU 2002232521 A1 AU2002232521 A1 AU 2002232521A1
Authority
AU
Australia
Prior art keywords
aging
compositions
methods
gene activation
identifying agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002232521A
Inventor
John M. Denu
Kirk G. Tanner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon Health and Science University
Original Assignee
Oregon Health and Science University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon Health and Science University filed Critical Oregon Health and Science University
Publication of AU2002232521A1 publication Critical patent/AU2002232521A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2002232521A 2000-11-11 2001-11-13 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging Abandoned AU2002232521A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24782700P 2000-11-11 2000-11-11
US60247827 2000-11-11
PCT/US2001/047159 WO2002038579A1 (en) 2000-11-11 2001-11-13 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging

Publications (1)

Publication Number Publication Date
AU2002232521A1 true AU2002232521A1 (en) 2002-05-21

Family

ID=22936535

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002232521A Abandoned AU2002232521A1 (en) 2000-11-11 2001-11-13 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging

Country Status (3)

Country Link
US (2) US7291606B2 (en)
AU (1) AU2002232521A1 (en)
WO (1) WO2002038579A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003045907A2 (en) 2001-11-21 2003-06-05 Albert Einstein College Of Medecine Of Yeshiva University Sir2 products and activities
ATE465406T1 (en) * 2004-11-15 2010-05-15 Erasmus Mc PREMATURE AGING MICE TO DEMONSTRATE THE ROLE OF DNA DAMAGE IN AGING AND INTERVENTION ON AGE-RELATED PATHOLOGY
JPWO2006070577A1 (en) * 2004-12-28 2008-06-12 独立行政法人海洋研究開発機構 Floating float and how to use it
US7838503B2 (en) * 2005-06-15 2010-11-23 Children's Medical Center Corporation Methods for extending the replicative lifespan of cells
US20110251104A1 (en) * 2010-04-09 2011-10-13 Can Ozbal Compositions and methods for detecting deacetylase activity
WO2012170494A1 (en) 2011-06-06 2012-12-13 Sirtris Pharmaceuticals, Inc. Non-enzymatic synthesis of o-acetyl-adp-ribose and analogues thereof
US11154947B2 (en) 2018-06-28 2021-10-26 Fanuc Corporation Laser processing system
US12441757B2 (en) * 2020-06-22 2025-10-14 Oregon Health & Science University Platform for screening NAD+ binding proteins in a cellular context

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5569650A (en) * 1993-06-11 1996-10-29 Sloan-Kettering Institute For Cancer Research C-nucleoside isosters of analogs thereof and pharmaceutical compositions

Also Published As

Publication number Publication date
US20070255045A1 (en) 2007-11-01
US20040067228A1 (en) 2004-04-08
WO2002038579A1 (en) 2002-05-16
US7291606B2 (en) 2007-11-06
US7521432B2 (en) 2009-04-21

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