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AU2002228912A1 - Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity - Google Patents

Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity

Info

Publication number
AU2002228912A1
AU2002228912A1 AU2002228912A AU2891202A AU2002228912A1 AU 2002228912 A1 AU2002228912 A1 AU 2002228912A1 AU 2002228912 A AU2002228912 A AU 2002228912A AU 2891202 A AU2891202 A AU 2891202A AU 2002228912 A1 AU2002228912 A1 AU 2002228912A1
Authority
AU
Australia
Prior art keywords
region
kinase activity
short peptides
selectively modulate
protein kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002228912A
Inventor
Shmuel Ben-Sasson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Boston Childrens Hospital
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Boston Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem, Boston Childrens Hospital filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of AU2002228912A1 publication Critical patent/AU2002228912A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2002228912A 2000-12-11 2001-12-11 Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity Abandoned AU2002228912A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/734,520 US20020115173A1 (en) 2000-12-11 2000-12-11 Short peptides from the 'A-region' of protein kinases which selectively modulate protein kinase activity
US09/734,520 2000-12-11
PCT/US2001/047443 WO2002048336A2 (en) 2000-12-11 2001-12-11 Short peptides from the 'a-region' of protein kinases which selectively modulate protein kinase activity

Publications (1)

Publication Number Publication Date
AU2002228912A1 true AU2002228912A1 (en) 2002-06-24

Family

ID=24952020

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002228912A Abandoned AU2002228912A1 (en) 2000-12-11 2001-12-11 Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity

Country Status (3)

Country Link
US (2) US20020115173A1 (en)
AU (1) AU2002228912A1 (en)
WO (1) WO2002048336A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
US20030219846A1 (en) * 2002-02-28 2003-11-27 Pfizer Inc. Assay for activity of the ActRIIB kinase
EP1995256A1 (en) 2003-07-30 2008-11-26 University of Pittsburgh of the Commonwealth System of Higher Education EPHA2 T-cell epitope agonists and uses therefor
RS53109B (en) 2003-07-30 2014-06-30 Rigel Pharmaceuticals Inc. 2,4 PIRIMIDINDIAMINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES
US7485297B2 (en) * 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody
US7871610B2 (en) * 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
CA2535171A1 (en) * 2003-08-12 2005-03-03 Dyax Corp. Tie1-binding ligands
JP4654418B2 (en) * 2004-03-31 2011-03-23 独立行政法人産業技術総合研究所 Epithelial cell growth promoter
US8158586B2 (en) 2005-04-11 2012-04-17 Pharmagap Inc. Inhibitors of protein kinases and uses thereof
CN105348203B (en) 2005-06-08 2018-09-18 里格尔药品股份有限公司 Inhibit the composition and method of JAK approach
US20070203161A1 (en) * 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
US8962643B2 (en) * 2006-02-24 2015-02-24 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
US20080213253A1 (en) * 2007-01-12 2008-09-04 Dyax Corp. Combination therapy for the treatment of cancer
HRP20170317T1 (en) 2008-02-15 2017-04-21 Rigel Pharmaceuticals, Inc. Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
AU2009244897B2 (en) 2008-04-16 2014-11-13 Alexion Pharmaceuticals, Inc. 2, 6-diamino- pyrimidin- 5-yl-carboxamides as syk or JAK kinases inhibitors
WO2009131687A2 (en) 2008-04-22 2009-10-29 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
EP2635557A2 (en) 2010-11-01 2013-09-11 Portola Pharmaceuticals, Inc. Nicotinamides as jak kinase modulators
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
CA2821515A1 (en) 2010-12-01 2012-06-07 Alder Biopharmaceuticals, Inc. Anti-ngf compositions and use thereof
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9029502B2 (en) 2010-12-20 2015-05-12 The Regents Of The University Of Michigan Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
US8877760B2 (en) 2011-11-23 2014-11-04 Portola Pharmaceuticals, Inc. Substituted pyrazine-2-carboxamide kinase inhibitors
EP2903970A4 (en) 2012-10-08 2016-11-30 Portola Pharm Inc Substituted pyrimidinyl kinase inhibitors
WO2021127185A1 (en) 2019-12-17 2021-06-24 The Board Of Regents Of The University Of Texas System Novel ddr1 antibodies and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174993B1 (en) * 1997-05-21 2001-01-16 The Children's Medical Center Corp. Short peptides which selectively modulate the activity of serine/threonine kinases
US6723694B1 (en) * 1997-05-21 2004-04-20 The Children's Medical Center Corp. Short peptides which selectively modulate intracellular signalling
WO2000018895A1 (en) * 1998-09-25 2000-04-06 The Children's Medical Center Corporation Short peptides which selectively modulate the activity of protein kinases
GB9902696D0 (en) * 1999-02-09 1999-03-31 Medical Res Council Screening methods

Also Published As

Publication number Publication date
US20020115173A1 (en) 2002-08-22
WO2002048336A3 (en) 2003-03-13
US20020137141A1 (en) 2002-09-26
WO2002048336A2 (en) 2002-06-20

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