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AU2002222057A1 - Methods and devices for transporting and concentrating an analyte present in a sample - Google Patents

Methods and devices for transporting and concentrating an analyte present in a sample

Info

Publication number
AU2002222057A1
AU2002222057A1 AU2002222057A AU2205702A AU2002222057A1 AU 2002222057 A1 AU2002222057 A1 AU 2002222057A1 AU 2002222057 A AU2002222057 A AU 2002222057A AU 2205702 A AU2205702 A AU 2205702A AU 2002222057 A1 AU2002222057 A1 AU 2002222057A1
Authority
AU
Australia
Prior art keywords
sample
transporting
concentrating
methods
analyte present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002222057A
Inventor
Patrice Caillat
Frederic Ginot
Patrick Pouteau
Pierre Puget
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Biomerieux SA
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA, Commissariat a lEnergie Atomique CEA filed Critical Biomerieux SA
Publication of AU2002222057A1 publication Critical patent/AU2002222057A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The present invention relates to a method of transporting an analyte present in a sample, to a method of concentrating an analyte present in a sample, and to a device for implementing these methods. In the method of transporting an analyte present in a sample of the present invention, a solution A in which the analyte is attached to magnetic particles is prepared from the sample; the solution A is introduced into a first container connected via a bottleneck to a second container; and the analyte attached to the magnetic particles is moved, by means of a magnetic system, from the first container to the second container via the bottleneck, the second container being filled with all or part of the solution A and/or with another solution.
AU2002222057A 2000-11-29 2001-11-27 Methods and devices for transporting and concentrating an analyte present in a sample Abandoned AU2002222057A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0015417 2000-11-29
FR0015417A FR2817343B1 (en) 2000-11-29 2000-11-29 METHOD AND DEVICES FOR TRANSPORTING AND CONCENTRATING AN ANALYTE PRESENT IN A SAMPLE
PCT/FR2001/003743 WO2002043865A1 (en) 2000-11-29 2001-11-27 Methods and devices for transporting and concentrating an analyte present in a sample

Publications (1)

Publication Number Publication Date
AU2002222057A1 true AU2002222057A1 (en) 2002-06-11

Family

ID=8857009

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002222057A Abandoned AU2002222057A1 (en) 2000-11-29 2001-11-27 Methods and devices for transporting and concentrating an analyte present in a sample

Country Status (7)

Country Link
US (1) US7569398B2 (en)
EP (1) EP1343586B1 (en)
AT (1) ATE293494T1 (en)
AU (1) AU2002222057A1 (en)
DE (1) DE60110256T2 (en)
FR (1) FR2817343B1 (en)
WO (1) WO2002043865A1 (en)

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US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US20060186055A1 (en) * 2003-07-16 2006-08-24 Toyo Boseki Kabushiki Kaisha Device for separation of biological components, and method of separation of biological components using the device
DE10354351B3 (en) * 2003-11-20 2005-06-16 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Method and apparatus for improved purification of a substance bound to paramagnetic microparticles
FR2863626B1 (en) * 2003-12-15 2006-08-04 Commissariat Energie Atomique METHOD AND DEVICE FOR DIVIDING A BIOLOGICAL SAMPLE BY MAGNETIC EFFECT
DE102004005193B4 (en) * 2004-02-02 2006-08-24 Medion Diagnostics Gmbh Device for separating individual particles from particle agglutinations
JP2006053090A (en) * 2004-08-13 2006-02-23 Alps Electric Co Ltd Inspection plate and inspection method using it
EP1815252B1 (en) * 2004-11-05 2012-10-10 Imec Method for transport of magnetic particles and devices therefor
US7502625B2 (en) * 2005-01-20 2009-03-10 Skyworks Solutions, Inc. Integrated multi-band transceiver for use in mobile communication device
CA2613094A1 (en) * 2005-07-01 2007-01-11 Promega Corporation Network of buoyant particles for biomolecule purification
DE102005039175A1 (en) * 2005-08-18 2007-02-22 Qiagen Gmbh Apparatus and method for separating magnetic particles from a liquid
WO2007070381A2 (en) * 2005-12-09 2007-06-21 Promega Corporation Nucleic acid purification with a binding matrix
JP5000666B2 (en) 2006-01-25 2012-08-15 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Device for analyzing fluids
WO2008094198A2 (en) * 2006-07-28 2008-08-07 Biosite Incorporated Devices and methods for performing receptor binding assays using magnetic particles
EP1939629A3 (en) * 2006-08-11 2011-03-09 Samsung Electronics Co., Ltd. Centrifugal Force Based Magnet Position Control Device and Disk-Shaped Micro Fluidic System
EP2384432B1 (en) * 2007-06-21 2016-12-28 Gen-Probe Incorporated Instrument and receptacles for performing processes
MX2010002079A (en) * 2007-08-24 2010-08-09 Advanced Liquid Logic Inc Bead manipulations on a droplet actuator.
US20100300978A1 (en) * 2007-09-19 2010-12-02 Agency For Science, Technology And Research Device, system and method for washing and isolating magnetic particles in a continous fluid flow
EP2072133A1 (en) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Multi-compartment device with magnetic particles
WO2009091320A1 (en) * 2008-01-17 2009-07-23 Ge Healthcare Bio-Sciences Ab Method for sample application
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
CN106771219B (en) 2010-06-17 2020-04-07 皇家飞利浦电子股份有限公司 Multi-epitope assay
JP6382699B2 (en) * 2014-11-28 2018-08-29 株式会社東芝 Micro analysis chip
CN105424922B (en) * 2015-12-09 2018-01-19 北京乐普医疗科技有限责任公司 The method of micro-fluidic chip and capture Applications of Cardiac Markers based on magnetic bead coated antibody
WO2018218053A1 (en) * 2017-05-24 2018-11-29 Northwestern University Devices and methods for rapid sample processing and analysis
ES2871925T3 (en) 2019-03-19 2021-11-02 Ace Medical Tech Co Ltd Device for classifying bioparticles using a force generated from light-induced dielectrophoresis and its method of operation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
WO1994026414A1 (en) 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
US5603760A (en) * 1995-09-18 1997-02-18 W. R. Grace & Co.-Conn. Cement admixture capable of inhibiting drying shrinkage and method of using same
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
WO1998010267A1 (en) * 1996-09-04 1998-03-12 Technical University Of Denmark A micro flow system for particle separation and analysis
FR2758884B1 (en) * 1997-01-30 1999-04-02 Bio Merieux METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM
EP2177627B1 (en) * 1999-02-23 2012-05-02 Caliper Life Sciences, Inc. Manipulation of microparticles in microfluidic systems

Also Published As

Publication number Publication date
DE60110256T2 (en) 2006-03-09
EP1343586B1 (en) 2005-04-20
US20040023273A1 (en) 2004-02-05
FR2817343B1 (en) 2003-05-09
ATE293494T1 (en) 2005-05-15
DE60110256D1 (en) 2005-05-25
WO2002043865A1 (en) 2002-06-06
EP1343586A1 (en) 2003-09-17
FR2817343A1 (en) 2002-05-31
US7569398B2 (en) 2009-08-04

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