AU2002221755A1 - Nucleotide and polypeptide sequence of human lysosomal acid lipase - Google Patents
Nucleotide and polypeptide sequence of human lysosomal acid lipaseInfo
- Publication number
- AU2002221755A1 AU2002221755A1 AU2002221755A AU2175502A AU2002221755A1 AU 2002221755 A1 AU2002221755 A1 AU 2002221755A1 AU 2002221755 A AU2002221755 A AU 2002221755A AU 2175502 A AU2175502 A AU 2175502A AU 2002221755 A1 AU2002221755 A1 AU 2002221755A1
- Authority
- AU
- Australia
- Prior art keywords
- nucleotide
- polypeptide sequence
- acid lipase
- lysosomal acid
- human lysosomal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101001004953 Homo sapiens Lysosomal acid lipase/cholesteryl ester hydrolase Proteins 0.000 title 1
- 102000048394 human LIPA Human genes 0.000 title 1
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 229920001184 polypeptide Chemical group 0.000 title 1
- 108090000765 processed proteins & peptides Chemical group 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24421500P | 2000-10-31 | 2000-10-31 | |
| US60/244,215 | 2000-10-31 | ||
| US25140100P | 2000-12-06 | 2000-12-06 | |
| US60/251,401 | 2000-12-06 | ||
| PCT/EP2001/012382 WO2002036754A2 (en) | 2000-10-31 | 2001-10-26 | Nucleotide and polypeptide sequence of human lysosomal acid lipase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002221755A1 true AU2002221755A1 (en) | 2002-05-15 |
Family
ID=26936395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002221755A Abandoned AU2002221755A1 (en) | 2000-10-31 | 2001-10-26 | Nucleotide and polypeptide sequence of human lysosomal acid lipase |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20040038365A1 (en) |
| AU (1) | AU2002221755A1 (en) |
| WO (1) | WO2002036754A2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040048249A1 (en) * | 2000-01-21 | 2004-03-11 | Tang Y. Tom | Novel nucleic acids and secreted polypeptides |
| BR0108077A (en) | 2000-02-04 | 2002-10-22 | Children S Hospital Res Founda | Process for reducing atherosclerotic plaques in a mammal, method for treating atherosclerosis in a mammal, composition, methods for providing biologically active lipid hydrolyzing protein or polypeptide or mixture thereof, for cells of a mammal having biologically hydrolyzing lipid protein or polypeptide active, to provide biologically active lysosomal acid lipase to cells of a mammal having biologically active lysosomal acid lipase deficiency, to provide biologically active lysosomal acid lipase to cells of a mammal with atherosclerosis, to treat wolman's disease in a mammal , for treatment of cholesterol ester storage disease in a mammal, and for treatment of atherosclerosis in a mammal |
| WO2002016597A2 (en) * | 2000-08-23 | 2002-02-28 | Incyte Genomics, Inc. | Lipid metabolism enzymes |
| US6867030B2 (en) * | 2001-03-29 | 2005-03-15 | Applera Corporation | Isolated human lipase proteins, nucleic acid molecules encoding human lipase proteins, and uses thereof |
| US20090297496A1 (en) * | 2005-09-08 | 2009-12-03 | Childrens Hospital Medical Center | Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases |
| HUE033217T2 (en) | 2010-04-23 | 2017-11-28 | Alexion Pharma Inc | Lysosomal storage disease enzyme |
| ME02062B (en) | 2010-09-09 | 2015-05-20 | Synageva Biopharma Corp | Use of lysosomal acid lipase for treating lysosomal acid lipase deficiency in patients |
| WO2012112677A2 (en) * | 2011-02-15 | 2012-08-23 | Children's Hospital Medical Center | Methods for treating lysosomal acid lipase deficiency |
| EP2675472A4 (en) | 2011-02-15 | 2014-09-17 | Synageva Biopharma Corp | Methods for treating lysosomal acid lipase deficiency |
| WO2014000058A1 (en) * | 2012-06-29 | 2014-01-03 | Garvan Institute Of Medical Research | Method of treating glucose metabolism disorders |
| KR102541256B1 (en) * | 2015-11-30 | 2023-06-12 | (주)아모레퍼시픽 | A melanoma preventing or treating agent through LIPA inhibition, and screening method thereof |
| US10857209B2 (en) | 2016-02-12 | 2020-12-08 | Indiana University Research And Technology Corporation | Lysosomal acid lipase and PPAR gamma ligands as immune therapies for cancer treatment |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0108077A (en) * | 2000-02-04 | 2002-10-22 | Children S Hospital Res Founda | Process for reducing atherosclerotic plaques in a mammal, method for treating atherosclerosis in a mammal, composition, methods for providing biologically active lipid hydrolyzing protein or polypeptide or mixture thereof, for cells of a mammal having biologically hydrolyzing lipid protein or polypeptide active, to provide biologically active lysosomal acid lipase to cells of a mammal having biologically active lysosomal acid lipase deficiency, to provide biologically active lysosomal acid lipase to cells of a mammal with atherosclerosis, to treat wolman's disease in a mammal , for treatment of cholesterol ester storage disease in a mammal, and for treatment of atherosclerosis in a mammal |
| US20040048269A1 (en) * | 2001-08-22 | 2004-03-11 | Griffin Jennifer A | Lipid metabolism enzymes |
-
2001
- 2001-10-26 AU AU2002221755A patent/AU2002221755A1/en not_active Abandoned
- 2001-10-26 WO PCT/EP2001/012382 patent/WO2002036754A2/en not_active Ceased
- 2001-10-26 US US10/415,093 patent/US20040038365A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040038365A1 (en) | 2004-02-26 |
| WO2002036754A3 (en) | 2002-10-17 |
| WO2002036754A2 (en) | 2002-05-10 |
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