[go: up one dir, main page]

AU2002218019A1 - Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells - Google Patents

Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells

Info

Publication number
AU2002218019A1
AU2002218019A1 AU2002218019A AU1801902A AU2002218019A1 AU 2002218019 A1 AU2002218019 A1 AU 2002218019A1 AU 2002218019 A AU2002218019 A AU 2002218019A AU 1801902 A AU1801902 A AU 1801902A AU 2002218019 A1 AU2002218019 A1 AU 2002218019A1
Authority
AU
Australia
Prior art keywords
cells
alloreactive
depleting
antigen
isolating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002218019A
Inventor
James G Bender
Mohammad Luqman
Dennis E Van Epps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexell Therapeutics Inc
Original Assignee
Nexell Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexell Therapeutics Inc filed Critical Nexell Therapeutics Inc
Publication of AU2002218019A1 publication Critical patent/AU2002218019A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2002218019A 2000-11-03 2001-10-31 Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells Abandoned AU2002218019A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70633700A 2000-11-03 2000-11-03
US09/706,337 2000-11-03
PCT/US2001/046333 WO2002036748A2 (en) 2000-11-03 2001-10-31 Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells

Publications (1)

Publication Number Publication Date
AU2002218019A1 true AU2002218019A1 (en) 2002-05-15

Family

ID=24837124

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002218019A Abandoned AU2002218019A1 (en) 2000-11-03 2001-10-31 Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells

Country Status (2)

Country Link
AU (1) AU2002218019A1 (en)
WO (1) WO2002036748A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2464606A1 (en) * 2001-10-24 2003-05-01 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Method of modulating the immunoactivity of an immunocompetent graft by progenipoietin
US7048922B2 (en) * 2002-05-29 2006-05-23 Demao Yang Stimulation of hematopoiesis by ex vivo activated immune cells
US7332158B2 (en) 2002-05-29 2008-02-19 Demao Yang Compositions and treatments for myelosuppression by ex vivo activated immune cells
CA2528727A1 (en) * 2003-06-10 2004-12-16 The University Of Melbourne Immunomodulating compositions, uses therefor and processes for their production
AU2008301240B2 (en) 2007-09-20 2014-07-31 St Vincent's Hospital Sydney Limited A method for identifying antigen-specific regulatory T cells
WO2016176193A1 (en) * 2015-04-27 2016-11-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for the selective depletion of alloreactive t lymphocytes from donor stem cell or lymphocyte grafts to prevent graft-versus-host disease
CN109666640B (en) * 2019-01-14 2020-06-16 武汉睿健医药科技有限公司 A method for pure culture of natural killer cells in vitro
WO2021163472A1 (en) * 2020-02-14 2021-08-19 The General Hospital Corporation Monitoring viability of organs for transplantation
WO2023006982A1 (en) * 2021-07-29 2023-02-02 Transimmune Ag Methods for selectively reducing immunogenicity in a transplant

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520563A (en) * 1997-07-21 2003-07-08 シーラス コーポレイション Methods for treating leukocytes, leukocyte compositions and methods of using the same
EP0996636B1 (en) * 1997-07-23 2005-01-26 Rijksuniversiteit te Leiden The ha-1 antigen
ATE428769T1 (en) * 1997-10-27 2009-05-15 Univ Rockefeller METHOD AND COMPOSITION FOR PRODUCING MATURE DENDRITIC CELLS
ATE406178T1 (en) * 1997-11-12 2008-09-15 Univ Pennsylvania PREVENTION OF IMMUNOREACTIVITY THROUGH DEPUPPERATION OR INHIBITION OF ANTIGEN-PRESENTING CELLS
JP2004510950A (en) * 1998-06-30 2004-04-08 ザ　ロックフェラー　ユニバーシティ Methods and Agents for Detection and Modulation of Cellular Immunity to Immunoimmune Antigens
WO2001030369A1 (en) * 1999-10-22 2001-05-03 Biotransplant, Inc. Process for inducing immunological tolerance for xenogeneic transplants

Also Published As

Publication number Publication date
WO2002036748A2 (en) 2002-05-10
WO2002036748A3 (en) 2003-10-02

Similar Documents

Publication Publication Date Title
AU1803601A (en) Methods and compositions for the introduction of molecules into cells
AU2002319780A1 (en) Alternative compositions and methods for the culture of stem cells
AU9582398A (en) Methods and devices for the long-term culture of hematopoietic progenitor cells
AU9231998A (en) Antigen presenting mesenchymal stem cells
AU2002303343A1 (en) Methods and reagents for cell transplantation
AU2002340167A1 (en) Anti-hla-dr antibodies and the methods of using thereof
AU2003211005A1 (en) Compositions comprising reproductive cell media and methods for using such compositions
AU2002325758A1 (en) Cultured stromal cells and uses thereof
AU6505299A (en) Methods for generating antigen-reactive t cells (in vitro)
AU2001280149A1 (en) Stem cell culture medium and culture method by using the same
AU3873200A (en) Mammalian cytokines; related reagents and methods
AU2000243137A1 (en) Methods for isolation, quantification, characterization and modulation of antigen-specific t cells
AU2002350489A1 (en) Method for separating bacterial cells and cell components
AU2003280687A1 (en) Composition for culturing multipotent stem cells and utilization of the same
AU9508998A (en) Methods and compositions for binding hematopoietic stem cells
AU2002218019A1 (en) Methods for depleting and isolating alloreactive and antigen-reactive t cells from hematopoietic donor cells
AU2003209297A1 (en) Methods and compositions for preserving the viability of photoreceptor cells
AU2995500A (en) Assessing immunological state of transplant recipients
AU2002248051A1 (en) Stabilized biocatalysts and methods of bioconversion using the same
AU2001275897A1 (en) Improvement of cell culture performance
AU2003299914A1 (en) Isolation and identification of cross-reactive t cells
AU7995600A (en) Compositions and methods for the incorporation of chemical substances into cells
WO2003004616A3 (en) Dendritic cell isolation methods
AU2003260815A1 (en) Method for the rapid assessment of the presence and viability of bacterial cells and use thereof________________________
AU3964799A (en) Compositions and methods for the characterization and transplantation of mammalian retinal stem cells