[go: up one dir, main page]

AU2002217929A1 - Modulation of gene expression using insulator binding proteins - Google Patents

Modulation of gene expression using insulator binding proteins

Info

Publication number
AU2002217929A1
AU2002217929A1 AU2002217929A AU1792902A AU2002217929A1 AU 2002217929 A1 AU2002217929 A1 AU 2002217929A1 AU 2002217929 A AU2002217929 A AU 2002217929A AU 1792902 A AU1792902 A AU 1792902A AU 2002217929 A1 AU2002217929 A1 AU 2002217929A1
Authority
AU
Australia
Prior art keywords
modulation
gene expression
binding proteins
insulator binding
insulator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002217929A
Inventor
Alan P. Wolffe (Deceased)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sangamo Therapeutics Inc
Original Assignee
Sangamo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sangamo Biosciences Inc filed Critical Sangamo Biosciences Inc
Publication of AU2002217929A1 publication Critical patent/AU2002217929A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/822—Reducing position variability, e.g. by the use of scaffold attachment region/matrix attachment region (SAR/MAR); Use of SAR/MAR to regulate gene expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2002217929A 2000-11-28 2001-11-28 Modulation of gene expression using insulator binding proteins Abandoned AU2002217929A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25367800P 2000-11-28 2000-11-28
US60/253,678 2000-11-28
PCT/US2001/044654 WO2002044376A2 (en) 2000-11-28 2001-11-28 Modulation of gene expression using insulator binding proteins

Publications (1)

Publication Number Publication Date
AU2002217929A1 true AU2002217929A1 (en) 2002-06-11

Family

ID=22961253

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002217929A Abandoned AU2002217929A1 (en) 2000-11-28 2001-11-28 Modulation of gene expression using insulator binding proteins

Country Status (3)

Country Link
US (2) US20030232781A1 (en)
AU (1) AU2002217929A1 (en)
WO (1) WO2002044376A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7261882B2 (en) * 2003-06-23 2007-08-28 Reagents Of The University Of Colorado Methods for treating neuropathic pain by administering IL-10 polypeptides
WO2005028630A2 (en) 2003-09-19 2005-03-31 Sangamo Biosciences, Inc. Engineered zinc finger proteins for regulation of gene expression
WO2005120582A2 (en) * 2004-06-07 2005-12-22 California Institute Of Technology Compositions and methods for inhibiting expression of hypoxia-inducible genes
KR20070060115A (en) 2004-09-16 2007-06-12 상가모 바이오사이언스 인코포레이티드 Compositions and Methods for Protein Production
KR100984602B1 (en) * 2004-11-18 2010-09-30 고쿠리츠다이가쿠호진 히로시마다이가쿠 Method and kit for expressing protein under regulation of the expression from related sequence formed by gene amplication and transformant
ES2696824T3 (en) * 2005-05-31 2019-01-18 Univ Colorado Regents Methods to supply genes
US8563314B2 (en) 2007-09-27 2013-10-22 Sangamo Biosciences, Inc. Methods and compositions for modulating PD1
CA2749965C (en) 2009-02-04 2018-09-11 Sangamo Biosciences, Inc. Methods and compositions for treating neuropathies
JP5932632B2 (en) 2009-03-20 2016-06-15 サンガモ バイオサイエンシーズ， インコーポレイテッド Modification of CXCR4 using modified zinc finger protein
EP2461819A4 (en) 2009-07-28 2013-07-31 Sangamo Biosciences Inc Methods and compositions for treating trinucleotide repeat disorders
AU2011256838B2 (en) 2010-05-17 2014-10-09 Sangamo Therapeutics, Inc. Novel DNA-binding proteins and uses thereof
CN108285491B (en) 2012-02-29 2021-08-10 桑格摩生物科学股份有限公司 Methods and compositions for treating huntington's disease
EP2906684B8 (en) 2012-10-10 2020-09-02 Sangamo Therapeutics, Inc. T cell modifying compounds and uses thereof
HUE046944T2 (en) 2013-07-18 2020-03-30 Xalud Therapeutics Inc A preparation for the treatment of inflammatory joint disease
SG10201913948PA (en) 2016-08-24 2020-03-30 Sangamo Therapeutics Inc Engineered target specific nucleases
US11401512B2 (en) 2018-02-08 2022-08-02 Sangamo Therapeutics, Inc. Engineered target specific nucleases
US11421007B2 (en) 2018-04-18 2022-08-23 Sangamo Therapeutics, Inc. Zinc finger protein compositions for modulation of huntingtin (Htt)
CN113015741A (en) 2018-09-18 2021-06-22 桑格摩生物治疗股份有限公司 Programmed cell death 1(PD1) specific nucleases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610053A (en) * 1993-04-07 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services DNA sequence which acts as a chromatin insulator element to protect expressed genes from cis-acting regulatory sequences in mammalian cells
US6919204B2 (en) * 2000-09-29 2005-07-19 Sangamo Biosciences, Inc. Modulation of gene expression using localization domains

Also Published As

Publication number Publication date
US20090181455A1 (en) 2009-07-16
WO2002044376A2 (en) 2002-06-06
WO2002044376A3 (en) 2003-05-30
WO2002044376A8 (en) 2003-02-13
WO2002044376A9 (en) 2002-10-03
US20030232781A1 (en) 2003-12-18

Similar Documents

Publication Publication Date Title
AU2002217929A1 (en) Modulation of gene expression using insulator binding proteins
AU4065000A (en) Antisense modulation of p38 mitogen activated protein kinase expression
AU2001270797A1 (en) Nucleic acid binding polypeptides
AU2002355551A1 (en) Antisense modulation of cholesteryl ester transfer protein expression
AU1221201A (en) Antisense modulation of y-box binding protein 1 expression
AU2002343356A1 (en) Antisense modulation of protein kinase r expression
AU2001266225A1 (en) Decondensation of dna
AU2001285302A1 (en) Antisense modulation of ubiquitin protein ligase expression
AU2002228805A1 (en) Antisense modulation of damage-specific dna binding protein 2, p48 expression
AU2743400A (en) Nucleic-acid binding proteins
AU2190801A (en) Binding protein
AU2000275763A1 (en) Expression of functional eukaryotic proteins
AU2002220215A1 (en) Novel proteins and nucleic acids encoding same
AU2001242625A1 (en) Gene sequence
AU2002213431A1 (en) Modulation of gene expression using localization domains
AU2001274566A1 (en) Novel protein and dna thereof
AU2002362800A1 (en) Modulation of the expression of genes dependent on stat-1
AU2001239756A1 (en) Novel proteins and nucleic acids encoding same
AU6911300A (en) Isomerase proteins
AU1320600A (en) Human rna binding proteins
AU2002346056A1 (en) Viral proteins capable of binding lar
AU2001259240A1 (en) Novel stmst protein and nucleic acid mocecules and uses therefor
AU2002249818A1 (en) Novel proteins and nucleic acids encoding same
AU2002248697A1 (en) Novel rgs9 protein binding interactions and methods of use thereof
AU2001286091A1 (en) Methods for identifying modulators of protein interactions