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AU2002217866A1 - Geldanamycin derivatives useful for the treatment of cancer - Google Patents

Geldanamycin derivatives useful for the treatment of cancer

Info

Publication number
AU2002217866A1
AU2002217866A1 AU2002217866A AU1786602A AU2002217866A1 AU 2002217866 A1 AU2002217866 A1 AU 2002217866A1 AU 2002217866 A AU2002217866 A AU 2002217866A AU 1786602 A AU1786602 A AU 1786602A AU 2002217866 A1 AU2002217866 A1 AU 2002217866A1
Authority
AU
Australia
Prior art keywords
cancer
treatment
derivatives useful
geldanamycin derivatives
geldanamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002217866A
Inventor
Jennifer A. Isaacs
Leonard M. Neckers
Christopher Nicchitta
Meredith F. Rosser
Edward A. Sausville
Kenneth M. Snader
B. Roa Vishnuvajjala
Wanping Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of AU2002217866A1 publication Critical patent/AU2002217866A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002217866A 2000-11-06 2001-11-06 Geldanamycin derivatives useful for the treatment of cancer Abandoned AU2002217866A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US24625800P 2000-11-06 2000-11-06
US60246258 2000-11-06
US27902001P 2001-03-27 2001-03-27
US60279020 2001-03-27
US28001601P 2001-03-30 2001-03-30
US60280016 2001-03-30
PCT/US2001/044172 WO2002036574A1 (en) 2000-11-06 2001-11-06 Geldanamycin derivatives useful for the treatment of cancer

Publications (1)

Publication Number Publication Date
AU2002217866A1 true AU2002217866A1 (en) 2002-05-15

Family

ID=27399909

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002217866A Abandoned AU2002217866A1 (en) 2000-11-06 2001-11-06 Geldanamycin derivatives useful for the treatment of cancer

Country Status (2)

Country Link
AU (1) AU2002217866A1 (en)
WO (1) WO2002036574A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872715B2 (en) 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
GB2384428A (en) * 2002-01-29 2003-07-30 Thromb X Nv Inhibitors of HIF
CA2525385A1 (en) 2003-05-12 2004-11-25 The Children's Hospital Of Philadelphia Grp94-based compositions and methods of use thereof
US20050020534A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites
US7241754B2 (en) 2003-06-13 2007-07-10 Kosan Biosciences, Inc. 2-Desmethyl ansamycin compounds
US6875863B1 (en) 2003-11-12 2005-04-05 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6855705B1 (en) 2003-11-12 2005-02-15 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6887993B1 (en) 2003-11-12 2005-05-03 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6870049B1 (en) 2003-11-12 2005-03-22 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US20050148496A1 (en) * 2003-11-26 2005-07-07 Entelos, Inc. Treatment of rheumatoid arthritis with hypoxia inducible factor-1alpha antagonists
US7259156B2 (en) 2004-05-20 2007-08-21 Kosan Biosciences Incorporated Geldanamycin compounds and method of use
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
US8466140B2 (en) 2007-09-10 2013-06-18 University Of Massachusetts Mitochondria-targeted anti-tumor agents
ES2325724B1 (en) 2008-03-11 2010-05-31 FUNDACION DE LA COMUNIDAD VALENCIANA "CENTRO DE INVESTIGACIONES PRINCIPE FELIPE" PHARMACEUTICAL COMPOSITION TO INHIBIT THE INDUCABLE TRANSCRIPTION FACTOR BY HYPOXIA. MODULATORS OF PATHOLOGICAL PROCESSES OF ANGIOGENESIS, ONCOGENESIS, INFLAMMATION, APOPTOSIS AND CELL THERAPY.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0706516A1 (en) * 1993-06-29 1996-04-17 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
AU2986800A (en) * 1999-02-08 2000-08-25 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods of inhibiting the hgf-met-upa-plasmin network

Also Published As

Publication number Publication date
WO2002036574A1 (en) 2002-05-10

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