AU2002216650A1 - Triazine derivatives as lpaat-b inhibitors and uses thereof - Google Patents

Triazine derivatives as lpaat-b inhibitors and uses thereof

Info

Publication number: AU2002216650A1
Authority: AU; Australia
Prior art keywords: lpaat; inhibitors; triazine derivatives; triazine; derivatives
Prior art date: 2000-10-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002216650A

Inventor

Lynn Bonham

Robert E. Finney

David M. Hollenback

J. Peter Klein

David W Leung

Scott A. Shaffer

Norina M. Tang

Thayer H. White

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-31

Filing date

2001-10-30

Publication date

2002-05-15

2001-10-30 Application filed by Individual filed Critical Individual

2002-05-15 Publication of AU2002216650A1 publication Critical patent/AU2002216650A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/50—Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/56—Preparation of melamine
- C07D251/58—Preparation of melamine from cyanamide, dicyanamide or calcium cyanamide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU2002216650A 2000-10-31 2001-10-30 Triazine derivatives as lpaat-b inhibitors and uses thereof Abandoned AU2002216650A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US24419500P	2000-10-31	2000-10-31
US60/244,195		2000-10-31
PCT/US2001/042837 WO2002036578A2 (en)	2000-10-31	2001-10-30	Triazine derivatives as lpaat-b inhibitors and uses thereof

Publications (1)

Publication Number	Publication Date
AU2002216650A1 true AU2002216650A1 (en)	2002-05-15

Family

ID=22921747

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002216650A Abandoned AU2002216650A1 (en)	2000-10-31	2001-10-30	Triazine derivatives as lpaat-b inhibitors and uses thereof

Country Status (3)

Country	Link
US (6)	US20020103195A1 (en)
AU (1)	AU2002216650A1 (en)
WO (1)	WO2002036578A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002036578A2 (en) *	2000-10-31	2002-05-10	Lynn Bonham	Triazine derivatives as lpaat-b inhibitors and uses thereof
PL369600A1 (en) *	2001-09-21	2005-05-02	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
EP1441683A4 (en) *	2001-10-12	2005-10-26	Univ New York	TRISUBSTITUTED TRIAZINE COMPOUNDS WITH ANTI-TUBULIN ACTIVITY, METHODS OF MAKING AND USING SAME
US7291616B2 (en)	2001-10-31	2007-11-06	Cell Therapeutics, Inc.	Aryl triazines as LPAAT-β inhibitors and uses thereof
US7419984B2 (en)	2002-10-17	2008-09-02	Cell Therapeutics, Inc.	Pyrimidines and uses thereof
CL2004000303A1 (en)	2003-02-20	2005-04-08	Tibotec Pharm Ltd	COMPOUNDS DERIVED FROM PYRIMIDINS AND TRIAZINES; PREPARATION PROCESS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO INHIBIT HIV REPLICATION.
RU2233837C1 (en) *	2003-03-31	2004-08-10	Кубанский государственный аграрный университет	2-chloro-4,5-bis-(nonyloxycarbonylamino)-1,3,5-triazine as semifinished product in synthesis of surfactant
RU2248972C2 (en) *	2003-03-31	2005-03-27	Кубанский государственный аграрный университет	2-diphenylamino-4,6-bis-(nonyloxycarbonylmethylthio)-1,3,5-triazine as antioxidant
RU2235093C1 (en) *	2003-03-31	2004-08-27	Кубанский государственный аграрный университет	4,6-bis-(nonyloxycarbonylmethylamino)-1,3,5-triazine 2- trimethylammonium chloride as surface-active substance
US6875781B2 (en)	2003-04-04	2005-04-05	Cell Therapeutics, Inc.	Pyridines and uses thereof
US7459472B2 (en)	2003-08-08	2008-12-02	Transtech Pharma, Inc.	Aryl and heteroaryl compounds, compositions, and methods of use
US20050148600A1 (en) *	2003-09-02	2005-07-07	Cell Therapeutics, Inc.	Methods for the treatment of obesity
US7592451B2 (en) *	2005-06-23	2009-09-22	New York University	Treatment for diabetes and obesity as well as method of screening compounds useful for such treatments
US20100323344A1 (en) *	2009-06-18	2010-12-23	Ferguson Monique R	Detection of hepatitis C virus RNA
CA2762434C (en) *	2011-12-16	2019-01-15	Her Majesty The Queen In Right Of Canada As Represented By The Minister Of National Defence	Molecular glasses with functionalizable groups

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670542B1 (en) *	1966-11-24	1971-07-01	Degussa	Substituted 2-anilino-4-morpholino-6-piperazino-s-triazines
ZA71598B (en) *	1970-02-06	1971-10-27	Gulf Research Development Co	Liquid formulations of triazine and thiolcarbamate herbicides and method of preparation
DE2311237A1 (en) *	1973-03-07	1974-09-12	Degussa	SUBSTITUTED S-TRIAZINE DERIVATIVES
CS197620B1 (en) *	1977-08-01	1980-05-30	Jan Kralovic	Agent for enhancement of root yield and sugar content of sugar beet
DE3202085A1 (en) *	1982-01-23	1983-08-04	Chemische Werke Hüls AG, 4370 Marl	USE OF CHLORINE-S-TRIAZINES SUBSTITUTED WITH ONE OR TWO CYCLOHEXYLAMINO GROUPS WITH AT LEAST 3 UNIQUE SUBSTITUTES OR WITH CYCLOPENTYLAMINO GROUPS AS A SELECTIVE AGAINST WEEDERS
DE3222147A1 (en) *	1982-06-11	1983-12-15	Chemische Werke Hüls AG, 4370 Marl	USE OF SUBSTITUTED THIOMETHYLCYCLOALKYLAMINO-S-TRIAZINE, IF ANY, AS A SELECTIVE AGENT AGAINST WEEDS AND POLLUTERS
JPH01261307A (en) *	1988-04-13	1989-10-18	Nippon Kayaku Co Ltd	Flowering promoter comprising triazine derivative
EP0438803B1 (en)	1990-01-26	1997-03-12	Immunomedics, Inc.	Vaccines against cancer and infectious diseases
DE4223890A1 (en) *	1992-02-19	1993-08-26	Merck Patent Gmbh	TRIAZINE DERIVATIVES
US5525606A (en) *	1994-08-01	1996-06-11	The United States Of America As Represented By The Department Of Health And Human Services	Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
US5702717A (en)	1995-10-25	1997-12-30	Macromed, Inc.	Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
US6136964A (en) *	1996-03-19	2000-10-24	Cell Therapeutics, Inc.	Mammalian lysophosphatidic acid acyltransferase
JPH11158073A (en) *	1997-09-26	1999-06-15	Takeda Chem Ind Ltd	Adenosine a3 antagonist
DE19753157A1 (en)	1997-11-29	1999-06-02	Celanese Gmbh	Process for the production of saturated alcohols
US6150362A (en)	1997-12-12	2000-11-21	Henkin; Jack	Triazine angiogenesis inhibitors
US5888793A (en) *	1998-02-25	1999-03-30	Incyte Pharmaceuticals, Inc.	Human lysophosphatidic acid acyltransferase
WO2000043372A1 (en) *	1999-01-22	2000-07-27	Elan Pharmaceuticals, Inc.	Acyl derivatives which treat vla-4 related disorders
AU2735201A (en) *	1999-12-28	2001-07-09	Pharmacopeia, Inc.	Pyrimidine and triazine kinase inhibitors
US20020065270A1 (en) *	1999-12-28	2002-05-30	Moriarty Kevin Joseph	N-heterocyclic inhibitors of TNF-alpha expression
WO2002036578A2 (en) *	2000-10-31	2002-05-10	Lynn Bonham	Triazine derivatives as lpaat-b inhibitors and uses thereof

2001
- 2001-10-30 WO PCT/US2001/042837 patent/WO2002036578A2/en not_active Ceased
- 2001-10-30 AU AU2002216650A patent/AU2002216650A1/en not_active Abandoned
- 2001-10-31 US US09/984,888 patent/US20020103195A1/en not_active Abandoned
2002
- 2002-09-06 US US10/236,084 patent/US20030100557A1/en not_active Abandoned
2003
- 2003-11-13 US US10/712,900 patent/US7064125B2/en not_active Expired - Fee Related
2005
- 2005-09-12 US US11/224,340 patent/US7199238B2/en not_active Expired - Fee Related
2006
- 2006-11-16 US US11/601,513 patent/US7608620B2/en not_active Expired - Fee Related
2009
- 2009-09-29 US US12/569,639 patent/US20100189726A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2002036578A9 (en)	2004-04-22
US20020103195A1 (en)	2002-08-01
US20030100557A1 (en)	2003-05-29
WO2002036578A2 (en)	2002-05-10
US20070072856A1 (en)	2007-03-29
WO2002036578A3 (en)	2003-04-03
US20100189726A1 (en)	2010-07-29
US20040162288A1 (en)	2004-08-19
US7064125B2 (en)	2006-06-20
US7608620B2 (en)	2009-10-27
US20060035896A1 (en)	2006-02-16
US7199238B2 (en)	2007-04-03

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