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AU2002212835A1 - Phosphorylation modifications of apoptin - Google Patents

Phosphorylation modifications of apoptin

Info

Publication number
AU2002212835A1
AU2002212835A1 AU2002212835A AU1283502A AU2002212835A1 AU 2002212835 A1 AU2002212835 A1 AU 2002212835A1 AU 2002212835 A AU2002212835 A AU 2002212835A AU 1283502 A AU1283502 A AU 1283502A AU 2002212835 A1 AU2002212835 A1 AU 2002212835A1
Authority
AU
Australia
Prior art keywords
apoptin
phosphorylation modifications
phosphorylation
modifications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002212835A
Inventor
Peter Donner
Dominik Mumberg
Mathieu Hubertus Maria Noteborn
Jennifer Leigh Rohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leadd BV
Original Assignee
Leadd BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leadd BV filed Critical Leadd BV
Publication of AU2002212835A1 publication Critical patent/AU2002212835A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2002212835A 2000-10-20 2001-10-19 Phosphorylation modifications of apoptin Abandoned AU2002212835A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24239700P 2000-10-20 2000-10-20
EP00203652.3 2000-10-20
EP00203652A EP1199363A1 (en) 2000-10-20 2000-10-20 Phosphorylation modifications of apoptin
US60/242,397 2000-10-20
PCT/NL2001/000771 WO2002032954A2 (en) 2000-10-20 2001-10-19 Phosphorylation modifications of apoptin

Publications (1)

Publication Number Publication Date
AU2002212835A1 true AU2002212835A1 (en) 2002-04-29

Family

ID=8172157

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002212835A Abandoned AU2002212835A1 (en) 2000-10-20 2001-10-19 Phosphorylation modifications of apoptin

Country Status (4)

Country Link
US (2) US7319034B2 (en)
EP (2) EP1199363A1 (en)
AU (1) AU2002212835A1 (en)
WO (1) WO2002032954A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003089467A1 (en) * 2002-04-19 2003-10-30 Leadd B.V. Fragments of apoptin
AU2003228132A1 (en) * 2002-04-19 2003-11-03 Leadd B.V. Aberrant-specific pathways
WO2007121576A1 (en) * 2006-04-21 2007-11-01 University Of Manitoba Methods of inducing apoptosis of cancerous cells using apoptin derivatives
US20070292401A1 (en) * 2006-06-20 2007-12-20 Harmon Alexander M Soft tissue repair and regeneration using stem cell products
US9403880B2 (en) 2010-11-26 2016-08-02 Institut Pasteur Identification of a human gyrovirus and applications
RU2541777C1 (en) * 2013-09-03 2015-02-20 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") RECOMBINANT PLASMID DNA pcDNA4-Apo-2NLS2 CARRYING SYNTHETIC GENE OF APOPTIN PROTEIN INDUCING p53-INDEPENDENT PROGRAMMED TUMOUR CELL DEATH
GB202013466D0 (en) * 2020-08-27 2020-10-14 Inst De Medicina Molecular Joaeo Lobo Antunes Genetic construct
CN114181322A (en) * 2021-12-13 2022-03-15 厦门医学院 A polypeptide that inhibits the proliferation of lung cancer cells
WO2025154104A1 (en) * 2024-01-20 2025-07-24 Ur Advanced Therapeutics Private Limited Non-cell penetrating, metacyclic synthetic peptides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9301272A (en) * 1993-07-20 1995-02-16 Aesculaap Bv Chicken Anemia Virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or coding sequences of that virus.
NL9002008A (en) * 1990-09-12 1992-04-01 Stichting Centr Diergeneeskund RECOMBINANT DNA AND RNA AND PRODUCTS DERIVED THEREFROM.
US5789567A (en) * 1994-07-06 1998-08-04 Cornell Research Foundation, Inc. Chicken infectious anemia virus vaccine
NZ309171A (en) * 1995-06-07 2000-04-28 Leadd Bv use of apoptin as an antitumour agent which specifically kills tumour and not normal cells
US6218103B1 (en) * 1997-04-16 2001-04-17 Arch Development Corporation Herpes simplex virus US3 and ICP4 as inhibitors of apoptosis
WO1998046740A1 (en) 1997-04-17 1998-10-22 Antivirals, Inc. Method of treating restenosis by antisense targeting of cmv
RU2214598C2 (en) 1997-08-12 2003-10-20 Леадд Б.В. Determination of transforming ability of agents
EP0927757A1 (en) 1997-12-03 1999-07-07 Leadd B.V. Methods and means for inducing apoptosis by interfering with Bip-like proteins

Also Published As

Publication number Publication date
US20100279947A1 (en) 2010-11-04
WO2002032954A3 (en) 2003-10-16
US20030199009A1 (en) 2003-10-23
WO2002032954A2 (en) 2002-04-25
US7319034B2 (en) 2008-01-15
EP1199363A1 (en) 2002-04-24
EP1373514A2 (en) 2004-01-02

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