AU2002211874A1 - Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors - Google Patents

Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors

Info

Publication number: AU2002211874A1
Authority: AU; Australia
Prior art keywords: polyaza; aza; hiv integrase; integrase inhibitors; carboxamides useful
Prior art date: 2000-10-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002211874A

Inventor

Neville J Anthony

Jennifer J. Bennett

Melissa Egbertson

Mark Embrey

Thorsten E Fisher

Timothy W. Funk

Robert P Gomez

James P. Guare

Samson M. Jolly

Michelle S. Kuo

H. Marie Langford

Jeffrey Y. Melamed

Debra S. Perlow

Lekhanh Tran

John S. Wai

Steven D. Young

Linghang Zhuang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-10-09

Publication date

2002-04-22

2001-10-09 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

2002-04-22 Publication of AU2002211874A1 publication Critical patent/AU2002211874A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AU2002211874A 2000-10-12 2001-10-09 Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors Abandoned AU2002211874A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US23970700P	2000-10-12	2000-10-12
US60/239,707		2000-10-12
US28165601P	2001-04-05	2001-04-05
US60/281,656		2001-04-05
PCT/US2001/042564 WO2002030931A2 (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors

Publications (1)

Publication Number	Publication Date
AU2002211874A1 true AU2002211874A1 (en)	2002-04-22

Family

ID=26932782

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AU1152702A Pending AU1152702A (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
AU2002211874A Abandoned AU2002211874A1 (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
AU2002211527A Ceased AU2002211527B2 (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU1152702A Pending AU1152702A (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2002211527A Ceased AU2002211527B2 (en)	2000-10-12	2001-10-09	Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors

Country Status (26)

Country	Link
US (2)	US6921759B2 (en)
EP (1)	EP1326865B1 (en)
JP (1)	JP4252797B2 (en)
KR (1)	KR20030036922A (en)
CN (1)	CN1469878A (en)
AR (1)	AR033845A1 (en)
AT (1)	ATE430745T1 (en)
AU (3)	AU1152702A (en)
BG (1)	BG107677A (en)
BR (1)	BR0114610A (en)
CA (1)	CA2425440C (en)
CZ (1)	CZ20031028A3 (en)
DE (1)	DE60138635D1 (en)
EA (1)	EA200300449A1 (en)
EE (1)	EE200300145A (en)
HU (1)	HUP0302367A2 (en)
IL (1)	IL155089A0 (en)
IS (1)	IS6760A (en)
MX (1)	MXPA03003263A (en)
NO (1)	NO20031672L (en)
NZ (1)	NZ525088A (en)
PE (1)	PE20020509A1 (en)
PL (1)	PL360944A1 (en)
SK (1)	SK4322003A3 (en)
WO (2)	WO2002030931A2 (en)
YU (1)	YU27903A (en)

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WO2003016309A1 (en)	2001-08-17	2003-02-27	Merck & Co., Inc.	Process for preparing 5-sulfonamido-8-hydroxy-1, 6-naphthyridine-7-carboxamides
AR036256A1 (en) *	2001-08-17	2004-08-25	Merck & Co Inc	SODIUM SALT OF AN HIV INTEGRAS INHIBITOR, PROCESSES FOR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT
EP1441735B1 (en)	2001-10-26	2006-02-22	Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A.	N-substituted hydroxypyrimidinone carboxamide inhibitors of hiv integrase
JP4351053B2 (en)	2001-10-26	2009-10-28	イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー	Dihydroxypyrimidine carboxamide HIV integrase inhibitor
EP1499391A2 (en) *	2002-04-10	2005-01-26	Merck & Co., Inc.	Pharmaceutical compositions containing an hiv integrase inhibitor and a nonionic surfactant

2001
- 2001-10-09 SK SK432-2003A patent/SK4322003A3/en unknown
- 2001-10-09 CN CNA018172970A patent/CN1469878A/en active Pending
- 2001-10-09 EE EEP200300145A patent/EE200300145A/en unknown
- 2001-10-09 CZ CZ20031028A patent/CZ20031028A3/en unknown
- 2001-10-09 WO PCT/US2001/042564 patent/WO2002030931A2/en not_active Ceased
- 2001-10-09 BR BR0114610-6A patent/BR0114610A/en not_active IP Right Cessation
- 2001-10-09 IL IL15508901A patent/IL155089A0/en unknown
- 2001-10-09 MX MXPA03003263A patent/MXPA03003263A/en unknown
- 2001-10-09 AU AU1152702A patent/AU1152702A/en active Pending
- 2001-10-09 KR KR10-2003-7005140A patent/KR20030036922A/en not_active Withdrawn
- 2001-10-09 EA EA200300449A patent/EA200300449A1/en unknown
- 2001-10-09 HU HU0302367A patent/HUP0302367A2/en unknown
- 2001-10-09 YU YU27903A patent/YU27903A/en unknown
- 2001-10-09 WO PCT/US2001/031456 patent/WO2002030930A2/en not_active Ceased
- 2001-10-09 JP JP2002534317A patent/JP4252797B2/en not_active Expired - Fee Related
- 2001-10-09 AU AU2002211874A patent/AU2002211874A1/en not_active Abandoned
- 2001-10-09 DE DE60138635T patent/DE60138635D1/en not_active Expired - Lifetime
- 2001-10-09 NZ NZ525088A patent/NZ525088A/en unknown
- 2001-10-09 AT AT01979582T patent/ATE430745T1/en not_active IP Right Cessation
- 2001-10-09 CA CA2425440A patent/CA2425440C/en not_active Expired - Fee Related
- 2001-10-09 PL PL01360944A patent/PL360944A1/en not_active Application Discontinuation
- 2001-10-09 EP EP01979582A patent/EP1326865B1/en not_active Expired - Lifetime
- 2001-10-09 AU AU2002211527A patent/AU2002211527B2/en not_active Ceased
- 2001-10-10 US US09/973,853 patent/US6921759B2/en not_active Expired - Fee Related
- 2001-10-11 PE PE2001001008A patent/PE20020509A1/en not_active Application Discontinuation
- 2001-10-11 AR ARP010104777A patent/AR033845A1/en not_active Application Discontinuation
2003
- 2003-03-26 BG BG107677A patent/BG107677A/en unknown
- 2003-03-27 IS IS6760A patent/IS6760A/en unknown
- 2003-04-11 NO NO20031672A patent/NO20031672L/en not_active Application Discontinuation
2005
- 2005-02-11 US US11/056,412 patent/US20050176718A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL155089A0 (en)	2003-10-31
BR0114610A (en)	2005-12-13
EA200300449A1 (en)	2003-10-30
JP4252797B2 (en)	2009-04-08
WO2002030930A2 (en)	2002-04-18
DE60138635D1 (en)	2009-06-18
CA2425440A1 (en)	2002-04-18
US20050176718A1 (en)	2005-08-11
IS6760A (en)	2003-03-27
US6921759B2 (en)	2005-07-26
CN1469878A (en)	2004-01-21
AU2002211527B2 (en)	2006-08-24
PE20020509A1 (en)	2002-06-20
PL360944A1 (en)	2004-09-20
EP1326865A2 (en)	2003-07-16
NO20031672D0 (en)	2003-04-11
BG107677A (en)	2003-11-28
WO2002030931A3 (en)	2002-10-24
CZ20031028A3 (en)	2003-08-13
SK4322003A3 (en)	2003-09-11
MXPA03003263A (en)	2003-06-06
ATE430745T1 (en)	2009-05-15
EP1326865B1 (en)	2009-05-06
EE200300145A (en)	2003-06-16
NZ525088A (en)	2004-11-26
AU1152702A (en)	2002-04-22
WO2002030930A3 (en)	2002-08-29
JP2004511483A (en)	2004-04-15
HUP0302367A2 (en)	2003-11-28
WO2002030931A2 (en)	2002-04-18
KR20030036922A (en)	2003-05-09
NO20031672L (en)	2003-06-05
CA2425440C (en)	2010-04-13
AR033845A1 (en)	2004-01-07
YU27903A (en)	2006-05-25
US20030055071A1 (en)	2003-03-20

Publication	Publication Date	Title
AU2002211874A1 (en)	2002-04-22	Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
AU2003248872A1 (en)	2004-01-23	Hiv integrase inhibitors
EP1282477B8 (en)	2004-04-14	Refractory articles
HUS1300066I1 (en)	2016-11-28	4-oxoquinoline compounds and utilization thereof as hiv integrase inhibitors
AU2001269700A1 (en)	2002-01-21	Heterocycle carboxamides as antiviral agents
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AU2002216028A1 (en)	2002-06-03	Novel carbamate-substituted pyrazolopyridine derivatives
AU2002250394A1 (en)	2002-10-08	Rho-kinase inhibitors
AU2002245709A1 (en)	2002-10-08	Rho-kinase inhibitors
AU6616400A (en)	2001-02-19	Hiv integrase inhibitors
AU2001269697A1 (en)	2002-01-21	Heterocycle carboxamides as antiviral agents
AU2001269699A1 (en)	2002-01-21	Heterocycle carboxamides as antiviral agents
AU2002339266A1 (en)	2003-04-22	Combustion process
AU3118200A (en)	2000-07-03	Hiv integrase inhibitors
PL370664A1 (en)	2005-05-30	Hiv integrase inhibitors
AU6989501A (en)	2001-12-24	Hiv integrase inhibitors
EP1086091A4 (en)	2001-10-10	Hiv integrase inhibitors
AU8009900A (en)	2001-04-23	Hiv integrase inhibitors
AU2003215469A1 (en)	2003-10-13	Pyridoxal-5-phosphate derivatives as hiv integrase inhibitors
AU2002224770A1 (en)	2002-04-02	Improved protocol for paracentesis
AU2002360673A1 (en)	2003-06-30	Gp41 inhibitor
AU2001233026A1 (en)	2001-08-07	Phosphodiesterases
AU2002243394A1 (en)	2002-06-24	Aryloxy piperidinyl derivatives for the treatment of depression
AU2001240939A1 (en)	2001-09-12	Isoquinoline derivatives as pde4 inhibitors
HK1066726A (en)	2005-04-01	Hiv integrase inhibitors