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AU2001239207A1 - Method of establishing at least one enveloped flow in a channel - Google Patents

Method of establishing at least one enveloped flow in a channel

Info

Publication number
AU2001239207A1
AU2001239207A1 AU2001239207A AU3920701A AU2001239207A1 AU 2001239207 A1 AU2001239207 A1 AU 2001239207A1 AU 2001239207 A AU2001239207 A AU 2001239207A AU 3920701 A AU3920701 A AU 3920701A AU 2001239207 A1 AU2001239207 A1 AU 2001239207A1
Authority
AU
Australia
Prior art keywords
channel
fluid
stub
enveloped
establishing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001239207A
Inventor
Ulrik Darling Larsen
Pieter Telleman
Anders Wolff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Denmark ApS
Original Assignee
Scandinavian Micro Biodevices ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scandinavian Micro Biodevices ApS filed Critical Scandinavian Micro Biodevices ApS
Publication of AU2001239207A1 publication Critical patent/AU2001239207A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409Handling samples, e.g. injecting samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413Hydrodynamic focussing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6095Micromachined or nanomachined, e.g. micro- or nanosize
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/0318Processes
    • Y10T137/0324With control of flow by a condition or characteristic of a fluid
    • Y10T137/0363For producing proportionate flow
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/87571Multiple inlet with single outlet
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/87571Multiple inlet with single outlet
    • Y10T137/87587Combining by aspiration
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/87571Multiple inlet with single outlet
    • Y10T137/87587Combining by aspiration
    • Y10T137/87595Combining of three or more diverse fluids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
  • Turbine Rotor Nozzle Sealing (AREA)
  • Micromachines (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)

Abstract

With a method of establishing an enveloped flow in a channel, in the channel an envelopment area ( 3 ) with a channel section ( 6, 7 ) is configured to which a stub with an outlet is connected, where the stub, which can be configured as a polyhedron, is arranged substantially at right-angles to the envelopment area and with the plane of the outlet substantially at right-angles to the channel section. An inlet channel ( 9, 11 ) and an outlet channel ( 8, 10 ) are connected to the envelopment area. By providing a narrowing-down in the cross-section of the channel in immediate extension of the envelopment area ( 3 ), a hydrodynamic focussing of the sample fluid is achieved when a fluid, such as a sample fluid, is introduced into the stub, and a carrier fluid is introduced into the inlet channel. The advantage of the invention is that since it is necessary only to have two fluid inlets, a relatively simple structure can be established, which can be built up in a monolithic manner, e.g. by injection molding.
AU2001239207A 2000-03-15 2001-03-09 Method of establishing at least one enveloped flow in a channel Abandoned AU2001239207A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000409 2000-03-15
DKPA200000409 2000-03-15
PCT/DK2001/000156 WO2001069203A2 (en) 2000-03-15 2001-03-09 Method of establishing at least one enveloped flow in a channel

Publications (1)

Publication Number Publication Date
AU2001239207A1 true AU2001239207A1 (en) 2001-09-24

Family

ID=8159326

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001239207A Abandoned AU2001239207A1 (en) 2000-03-15 2001-03-09 Method of establishing at least one enveloped flow in a channel

Country Status (7)

Country Link
US (1) US7096877B2 (en)
EP (1) EP1281059B1 (en)
JP (1) JP2003531360A (en)
AT (1) ATE418071T1 (en)
AU (1) AU2001239207A1 (en)
DE (1) DE60137036D1 (en)
WO (1) WO2001069203A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100519672B1 (en) * 2003-12-22 2005-10-11 주식회사 디지탈바이오테크놀러지 Channel Apparatus for Focusing a Fluid Flow
WO2007005907A1 (en) * 2005-07-01 2007-01-11 Honeywell International, Inc. A molded cartridge with 3-d hydrodynamic focusing
JP2009537826A (en) * 2006-05-17 2009-10-29 ルミネックス・コーポレーション Chip-based flow cytometer-type system for analyzing fluorescently labeled particles
US20080034552A1 (en) * 2006-08-10 2008-02-14 Ventra Group, Inc. Hinge for a motor vehicle
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
CN108051590B (en) 2013-09-13 2020-12-11 Symbolics有限责任公司 Lateral tomography detection using 2D assay and control signal readout modes
EP3201599A1 (en) 2014-09-30 2017-08-09 FOSS Analytical A/S Method, device and system for hydrodynamic flow focusing
KR102887643B1 (en) * 2020-01-14 2025-11-19 포스 애널리터컬 에이/에스 Fluid dynamic focusing device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1119515A (en) * 1912-10-31 1914-12-01 Kaelteindustrie Mit Beschraenkter Haftung Ges Injector.
JPS58114754A (en) * 1981-12-28 1983-07-08 Gadelius Kk Electrical dust precipitator
US4519423A (en) * 1983-07-08 1985-05-28 University Of Southern California Mixing apparatus using a noncircular jet of small aspect ratio
US4600302A (en) 1984-03-26 1986-07-15 Becton, Dickinson And Company Flow cytometry apparatus with uniform incoherent light excitation
US5034163A (en) * 1986-07-16 1991-07-23 Outboard Marine Corporation Modular side-draft carburetor
JPS63262565A (en) 1987-04-20 1988-10-28 Hitachi Ltd flow cell
DE3832901A1 (en) 1987-10-02 1989-04-20 Hitachi Ltd PARTICLE MEASURING DEVICE
US4988619A (en) * 1987-11-30 1991-01-29 United States Department Of Energy Flow cytometry apparatus
US4917152A (en) * 1989-08-14 1990-04-17 Decker William T Fluid injector
US6196524B1 (en) * 1993-10-01 2001-03-06 Outboard Marine Corporation Fuel enrichment system
JP3392586B2 (en) * 1995-05-31 2003-03-31 独立行政法人産業技術総合研究所 Photoacoustic densitometer
JPH0989749A (en) * 1995-09-25 1997-04-04 Nikkiso Co Ltd Air flow controller and powder particle size analyzer
US5808737A (en) * 1996-02-29 1998-09-15 Sienna Biotech, Inc. Pre-analysis chamber for a flow particle analyzer
EP0838259A1 (en) * 1996-10-23 1998-04-29 Sulzer Chemtech AG Device for feeding additives to a high viscous liquid stram
US6159739A (en) * 1997-03-26 2000-12-12 University Of Washington Device and method for 3-dimensional alignment of particles in microfabricated flow channels
US6007775A (en) * 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor

Also Published As

Publication number Publication date
WO2001069203A3 (en) 2002-09-26
EP1281059A2 (en) 2003-02-05
US20040025950A1 (en) 2004-02-12
ATE418071T1 (en) 2009-01-15
JP2003531360A (en) 2003-10-21
DE60137036D1 (en) 2009-01-29
WO2001069203A2 (en) 2001-09-20
EP1281059B1 (en) 2008-12-17
US7096877B2 (en) 2006-08-29

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