AU2001238458A1 - Improved assay for protein tyrosine phosphatases - Google Patents
Improved assay for protein tyrosine phosphatasesInfo
- Publication number
- AU2001238458A1 AU2001238458A1 AU2001238458A AU3845801A AU2001238458A1 AU 2001238458 A1 AU2001238458 A1 AU 2001238458A1 AU 2001238458 A AU2001238458 A AU 2001238458A AU 3845801 A AU3845801 A AU 3845801A AU 2001238458 A1 AU2001238458 A1 AU 2001238458A1
- Authority
- AU
- Australia
- Prior art keywords
- protein tyrosine
- tyrosine phosphatases
- improved assay
- assay
- improved
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000002727 Protein Tyrosine Phosphatase Human genes 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 108020000494 protein-tyrosine phosphatase Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18176900P | 2000-02-14 | 2000-02-14 | |
| US60/181,769 | 2000-02-14 | ||
| PCT/US2001/005180 WO2001061031A2 (en) | 2000-02-14 | 2001-02-13 | Improved assay for protein tyrosine phosphatases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001238458A1 true AU2001238458A1 (en) | 2001-08-27 |
Family
ID=22665713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001238458A Abandoned AU2001238458A1 (en) | 2000-02-14 | 2001-02-13 | Improved assay for protein tyrosine phosphatases |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20020009762A1 (en) |
| EP (1) | EP1257824A2 (en) |
| AU (1) | AU2001238458A1 (en) |
| CA (1) | CA2435507A1 (en) |
| WO (1) | WO2001061031A2 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001064939A2 (en) * | 2000-03-02 | 2001-09-07 | Morphochem Ag | Process for obtaining inhibitors/activators of an enzyme |
| WO2003025199A2 (en) | 2001-09-18 | 2003-03-27 | Millennium Pharmaceuticals, Inc. | Mid 4460, a human tyrosine phosphatase family member and uses therefor |
| AU2003299466A1 (en) * | 2002-05-03 | 2004-06-07 | Molecular Probes, Inc. | Compositions and methods for detection and isolation of phosphorylated molecules |
| US20040171034A1 (en) * | 2002-05-03 | 2004-09-02 | Brian Agnew | Compositions and methods for detection and isolation of phosphorylated molecules |
| US20060127965A1 (en) * | 2002-12-31 | 2006-06-15 | Charlie Rodi | Bindingzyme arrays and high-throughput proteomic methods |
| CA2514363A1 (en) * | 2003-02-12 | 2004-08-26 | Transtech Pharma, Inc. | Substituted azole derivatives as therapeutic agents |
| US20040186151A1 (en) * | 2003-02-12 | 2004-09-23 | Mjalli Adnan M.M. | Substituted azole derivatives as therapeutic agents |
| EP1730118A1 (en) * | 2004-02-12 | 2006-12-13 | Transtech Pharma, Inc. | Substituted azole derivatives, compositions, and methods of use |
| AU2007211319B9 (en) | 2006-01-30 | 2012-05-31 | Vtv Therapeutics Llc | Substituted imidazole derivatives and their use as PTPase inhibitors |
| US20080171351A1 (en) * | 2006-05-22 | 2008-07-17 | University Of Notre Dame Du Lac | Probes for anionic cell surface detection |
| US20130078660A1 (en) * | 2010-03-23 | 2013-03-28 | Salk Institute For Biological Studies | Methods and compositions for detecting protein modifications |
| JP5854545B1 (en) * | 2015-04-30 | 2016-02-09 | 大学共同利用機関法人自然科学研究機構 | Screening method for inhibitors of receptor protein tyrosine phosphatases belonging to R3RPTP subfamily |
| CN113899902B (en) * | 2020-06-22 | 2024-10-29 | 上海科技大学 | A method for identifying tyrosine phosphatase substrates |
| CN111812183B (en) * | 2020-07-27 | 2022-05-17 | 山东理工大学 | Preparation method and application of intramolecular photo-electrochemical sensor |
| CN116183565A (en) * | 2022-12-09 | 2023-05-30 | 青岛大学 | Method for Rapidly Detecting the Binding Ability of Small Molecule Compounds to FXR Receptor |
| CN117736257B (en) * | 2023-12-18 | 2024-07-19 | 嘉华药锐科技(北京)有限公司 | Tyrosine phosphorylation polypeptide enrichment method and application thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE920151A1 (en) * | 1991-01-18 | 1992-07-29 | Univ New York | A novel expression-cloning method for identifying target¹proteins for receptor tyrosine kinases and novel human grb¹proteins |
| US5804395A (en) * | 1995-12-01 | 1998-09-08 | The United States Of America As Represented By The Secretary Of The Navy | Fluorescence polarization assays of enzymes and substrates therefore |
| US5912138A (en) * | 1996-07-25 | 1999-06-15 | Cold Spring Harbor Laboratory | Substrate trapping protein tyrosine phosphatases |
| ATE233325T1 (en) * | 1997-12-05 | 2003-03-15 | Upjohn Co | FLUORESCENCE-BASED HTS (HIGH THROUGHPUT SCREENING) ASSAY METHODS FOR PROTEIN KINASE AND PHOSPHATASE |
-
2001
- 2001-02-13 EP EP01910900A patent/EP1257824A2/en not_active Withdrawn
- 2001-02-13 WO PCT/US2001/005180 patent/WO2001061031A2/en not_active Ceased
- 2001-02-13 CA CA002435507A patent/CA2435507A1/en not_active Abandoned
- 2001-02-13 US US09/788,626 patent/US20020009762A1/en not_active Abandoned
- 2001-02-13 AU AU2001238458A patent/AU2001238458A1/en not_active Abandoned
-
2006
- 2006-02-13 US US11/352,949 patent/US20070015231A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020009762A1 (en) | 2002-01-24 |
| CA2435507A1 (en) | 2001-08-23 |
| WO2001061031A2 (en) | 2001-08-23 |
| US20070015231A1 (en) | 2007-01-18 |
| WO2001061031A9 (en) | 2002-10-17 |
| WO2001061031A3 (en) | 2002-03-07 |
| EP1257824A2 (en) | 2002-11-20 |
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