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AU2001238346A1 - Modification of biopolymers for improved drug delivery - Google Patents

Modification of biopolymers for improved drug delivery

Info

Publication number
AU2001238346A1
AU2001238346A1 AU2001238346A AU3834601A AU2001238346A1 AU 2001238346 A1 AU2001238346 A1 AU 2001238346A1 AU 2001238346 A AU2001238346 A AU 2001238346A AU 3834601 A AU3834601 A AU 3834601A AU 2001238346 A1 AU2001238346 A1 AU 2001238346A1
Authority
AU
Australia
Prior art keywords
biopolymers
modification
drug delivery
improved drug
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238346A
Inventor
Pericles Calias
Robert J. Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of AU2001238346A1 publication Critical patent/AU2001238346A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AU2001238346A 2000-02-15 2001-02-15 Modification of biopolymers for improved drug delivery Abandoned AU2001238346A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18255800P 2000-02-15 2000-02-15
US60182558 2000-02-15
US21150800P 2000-06-14 2000-06-14
US60211508 2000-06-14
PCT/US2001/004925 WO2001060412A2 (en) 2000-02-15 2001-02-15 Modification of biopolymers for improved drug delivery

Publications (1)

Publication Number Publication Date
AU2001238346A1 true AU2001238346A1 (en) 2001-08-27

Family

ID=26878197

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238346A Abandoned AU2001238346A1 (en) 2000-02-15 2001-02-15 Modification of biopolymers for improved drug delivery

Country Status (6)

Country Link
EP (1) EP1263472A2 (en)
JP (1) JP2003522806A (en)
AU (1) AU2001238346A1 (en)
CA (1) CA2400205A1 (en)
IL (1) IL151024A0 (en)
WO (1) WO2001060412A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03006294A (en) * 2001-01-18 2003-09-16 Merck Patent Gmbh Bifunctional fusion proteins with glucocerebrosidase activity.
US7723296B2 (en) 2001-01-18 2010-05-25 Genzyme Corporation Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
WO2004060404A1 (en) * 2002-12-27 2004-07-22 Chugai Seiyaku Kabushiki Kaisha Drug carrier
CA2528067C (en) 2003-06-05 2015-08-04 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Poly-gamma-glutamic acid conjugates for eliciting immune responses directed against bacilli
US7365223B2 (en) * 2003-06-18 2008-04-29 Nst Neurosurvival Technologies Ltd Method for selective targeting of apoptotic cells and small molecule ligands used thereof
CA2542041C (en) * 2003-10-10 2014-12-09 Cellular Bioengineering, Inc. Methods and compositions for growing corneal endothelial and related cells on biopolymers and creation of artifical corneal transplants
US7625736B2 (en) 2004-06-04 2009-12-01 The United States Of America As Represented By The Department Of Health And Human Services Methods for preparing immunogenic conjugates
US8143391B2 (en) 2004-09-07 2012-03-27 Chugai Seiyaku Kabushiki Kaisha Process for producing water-soluble hyaluronic acid modification
EP1877099B1 (en) 2005-04-06 2012-09-19 Genzyme Corporation Therapeutic conjugates comprising a lysosomal enzyme, polysialic acid and a targeting moiety
WO2007008904A2 (en) 2005-07-08 2007-01-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Targeting poly-gamma-glutamic acid to treat staphylococcus epidermidis and related infections
PL2457920T3 (en) 2007-01-18 2018-03-30 Genzyme Corporation Oligosaccharides comprising an aminooxy group and conjugates thereof
MX2011006347A (en) 2008-12-16 2011-09-06 Genzyme Corp Oligosaccharide-protein conjugates.
WO2012118189A1 (en) 2011-03-03 2012-09-07 中外製薬株式会社 Hyaluronic acid derivative modified by amino-carbonic acid
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
CA2884142C (en) 2012-09-05 2020-11-10 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid derivative having amino acid and steryl group introduced thereinto
KR102049568B1 (en) * 2013-04-01 2019-11-27 삼성전자주식회사 Composition for nucleic acid delivery containing hyaluronic acid
GB201602359D0 (en) * 2016-02-10 2016-03-23 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
CN108440684A (en) * 2018-03-22 2018-08-24 华侨大学 A kind of NI-Cys-Alg self-assembled nanometers carrier and its preparation method and application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7759291A (en) * 1990-03-29 1991-10-21 Gilead Sciences, Inc. Oligonucleotide-transport agent disulfide conjugates
US5169934A (en) * 1990-05-14 1992-12-08 Anergen, Inc. Intracellularly cleavable compounds
US6335434B1 (en) * 1998-06-16 2002-01-01 Isis Pharmaceuticals, Inc., Nucleosidic and non-nucleosidic folate conjugates
CA2122717C (en) * 1991-11-08 2003-07-15 David C. Anderson Hemoglobins as drug delivery agents
US5902795A (en) 1992-06-16 1999-05-11 Trustees Of Tufts College Oligosaccharides reactive with hyaluronan-binding protein and their methods of use
US5329029A (en) 1992-11-05 1994-07-12 Wan Barbara Y Phosphatidylalkanolamine derivatives and their use in generating phospholipid conjugates
DK0693924T4 (en) * 1993-02-22 2008-08-04 Abraxis Bioscience Inc Process for (in vivo) delivery of biological materials and compositions suitable therefor
US5354853A (en) 1993-03-12 1994-10-11 Genzyme Corporation Phospholipid-saccharide conjugates
BR9809138A (en) * 1997-05-21 2001-08-28 Trustees For The Leland Stanfo Conjugate and method to increase the transport of a selected compound across a biological membrane
US5932552A (en) 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production

Also Published As

Publication number Publication date
WO2001060412A2 (en) 2001-08-23
WO2001060412A3 (en) 2002-01-24
IL151024A0 (en) 2003-02-12
CA2400205A1 (en) 2001-08-23
EP1263472A2 (en) 2002-12-11
JP2003522806A (en) 2003-07-29

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