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AU2001236471A1 - Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors - Google Patents

Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors

Info

Publication number
AU2001236471A1
AU2001236471A1 AU2001236471A AU3647101A AU2001236471A1 AU 2001236471 A1 AU2001236471 A1 AU 2001236471A1 AU 2001236471 A AU2001236471 A AU 2001236471A AU 3647101 A AU3647101 A AU 3647101A AU 2001236471 A1 AU2001236471 A1 AU 2001236471A1
Authority
AU
Australia
Prior art keywords
imidazopyridines
bradykinin
receptors
selective modulators
azacyclic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001236471A
Inventor
Kevin J. Hodgetts
Alan Hutchison
Richard Lew
George D Maynard
John M Peterson
Kenneth Shaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurogen Corp
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of AU2001236471A1 publication Critical patent/AU2001236471A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001236471A 2000-01-18 2001-01-17 Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors Abandoned AU2001236471A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17670100P 2000-01-18 2000-01-18
US60/176,701 2000-01-18
PCT/US2001/001601 WO2001053298A1 (en) 2000-01-18 2001-01-17 Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors

Publications (1)

Publication Number Publication Date
AU2001236471A1 true AU2001236471A1 (en) 2001-07-31

Family

ID=22645477

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001236471A Abandoned AU2001236471A1 (en) 2000-01-18 2001-01-17 Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors

Country Status (3)

Country Link
US (1) US6420365B1 (en)
AU (1) AU2001236471A1 (en)
WO (1) WO2001053298A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2421594A1 (en) 2000-11-10 2002-05-16 John Arnold Werner 3-substituted oxindole beta 3 agonists
MXPA03008681A (en) 2001-03-27 2004-04-02 Neurogen Corp (oxo-pyrazolo[1,5a]pyrimidin-2-yl)alkyl-carboxamides.
IL159811A0 (en) 2001-07-13 2004-06-20 Neurogen Corp Heteroaryl substituted fused bicyclic heteroaryl compounds as gabaa receptor ligands
US7208505B2 (en) 2001-08-14 2007-04-24 Eli Lilly And Company β3 adrenergic agonists
WO2003016276A2 (en) 2001-08-14 2003-02-27 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
DE60204718T2 (en) 2001-11-20 2006-05-18 Eli Lilly And Co., Indianapolis 3-SUBSTITUTED OXINDOL BETA 3 AGONISTS
US7071208B2 (en) 2001-11-20 2006-07-04 Eli Lilly And Company β3 Adrenergic agonists
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
KR20070055563A (en) 2004-08-23 2007-05-30 와이어쓰 Oxazolo-naphthyl acid as a modulator of plasminogen activator inhibitor type 1 (PAI-1) useful in the treatment of thrombosis and cardiovascular disease
MX2007002177A (en) 2004-08-23 2007-04-02 Wyeth Corp Pyrrolo-naphthyl acids as pai-1 inhibitors.
WO2006023866A2 (en) 2004-08-23 2006-03-02 Wyeth Thiazolo-naphthyl acids as inhibitors of plasminogen activator inhibitor-1
DE102005016547A1 (en) * 2005-04-08 2006-10-12 Grünenthal GmbH Substituted 5,6,7,8-tetrahydro-imidazo (1,2-a) pyridin-2-ylamine compounds and their use for the preparation of medicaments
CA2634923C (en) 2005-12-23 2015-05-05 Ariad Pharmaceuticals, Inc. Acetylenic bicyclic heteroaryl compounds useful as kinase inhibitors
WO2008045688A1 (en) * 2006-10-06 2008-04-17 Boehringer Ingelheim International Gmbh Chymase inhibitors
US8173668B1 (en) 2007-06-05 2012-05-08 Alcon Research, Ltd. Use of non-peptidic bradykinin receptor agonists to treat ocular hypertension and glaucoma
US7807629B1 (en) * 2007-06-05 2010-10-05 Alcon Research, Ltd. Use of bradykinin and related B2R agonists to treat ocular hypertension and glaucoma
PL2690101T3 (en) * 2007-12-19 2015-12-31 Genentech Inc 5-Anilinoimidazopyridines and Methods of Use
WO2013144113A1 (en) * 2012-03-26 2013-10-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for prevention or treatment of ischemia related organ damage
US20170305943A1 (en) * 2014-05-21 2017-10-26 Taxis Pharmaceuticals, Inc. Compounds for the treatment of bacterial infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5438064A (en) * 1991-12-23 1995-08-01 American Home Products Corporation Derivatives of 4-anilinoquinoline-3-carboxamide as analgesic agents
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
JPH09176165A (en) * 1995-12-25 1997-07-08 Nippon Nohyaku Co Ltd Imidazo [1,2-a] pyridine derivative, process for producing the same and use thereof
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases

Also Published As

Publication number Publication date
WO2001053298A9 (en) 2002-10-17
US6420365B1 (en) 2002-07-16
WO2001053298A1 (en) 2001-07-26

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