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AU2001235783A1 - Therapeutic compositions for pulmonary delivery - Google Patents

Therapeutic compositions for pulmonary delivery

Info

Publication number
AU2001235783A1
AU2001235783A1 AU2001235783A AU3578301A AU2001235783A1 AU 2001235783 A1 AU2001235783 A1 AU 2001235783A1 AU 2001235783 A AU2001235783 A AU 2001235783A AU 3578301 A AU3578301 A AU 3578301A AU 2001235783 A1 AU2001235783 A1 AU 2001235783A1
Authority
AU
Australia
Prior art keywords
pulmonary delivery
therapeutic compositions
therapeutic agent
microparticles
obtainable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001235783A
Inventor
Glen Patrick Martyn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Healthcare UK Ltd
Original Assignee
Quadrant Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadrant Healthcare UK Ltd filed Critical Quadrant Healthcare UK Ltd
Publication of AU2001235783A1 publication Critical patent/AU2001235783A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Microparticles that are obtainable by spray-freeze-drying a solution comprising a water-soluble, matrix-forming polymer and a therapeutic agent may be useful for pulmonary delivery of the therapeutic agent.
AU2001235783A 2000-02-29 2001-02-27 Therapeutic compositions for pulmonary delivery Abandoned AU2001235783A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0004827 2000-02-29
GBGB0004827.2A GB0004827D0 (en) 2000-02-29 2000-02-29 Compositions
PCT/GB2001/000834 WO2001064188A1 (en) 2000-02-29 2001-02-27 Therapeutic compositions for pulmonary delivery

Publications (1)

Publication Number Publication Date
AU2001235783A1 true AU2001235783A1 (en) 2001-09-12

Family

ID=9886657

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001235783A Abandoned AU2001235783A1 (en) 2000-02-29 2001-02-27 Therapeutic compositions for pulmonary delivery

Country Status (11)

Country Link
US (2) US20030133879A1 (en)
EP (1) EP1259228B1 (en)
JP (1) JP2003525232A (en)
AT (1) ATE454136T1 (en)
AU (1) AU2001235783A1 (en)
CA (1) CA2401696A1 (en)
DE (1) DE60140997D1 (en)
ES (1) ES2339423T3 (en)
GB (1) GB0004827D0 (en)
PT (1) PT1259228E (en)
WO (1) WO2001064188A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011807D0 (en) * 2000-05-16 2000-07-05 Quadrant Holdings Cambridge Formulation for inhalation
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
US6749845B2 (en) * 2001-02-15 2004-06-15 Aeropharm Technology, Inc. Modulated release particles for lung delivery
WO2002101412A2 (en) * 2001-06-08 2002-12-19 Powderject Vaccines, Inc. Spray freeze-dried compositions
US8524279B2 (en) 2001-11-01 2013-09-03 Novartis Ag Spray drying methods and related compositions
BR0214280A (en) * 2001-11-19 2005-01-11 Becton Dickinson Co Pharmaceutical composition in particulate form
GB0129489D0 (en) * 2001-12-10 2002-01-30 Quadrant Healthcare Uk Ltd Sustained-release compositions
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
GB2399084B (en) * 2002-07-30 2007-01-31 Univ Liverpool Porous beads and method of production thereof
DE10339197A1 (en) * 2003-08-22 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried amorphous powder with low residual moisture and good storage stability
US7723712B2 (en) * 2006-03-17 2010-05-25 Micron Technology, Inc. Reduced power consumption phase change memory and methods for forming the same
US20140155347A1 (en) * 2011-05-30 2014-06-05 Novozymes Biopharma Dk A/S Spray Drying of High Molecular Weight Hyaluronic Acid
WO2013071316A2 (en) * 2012-12-28 2013-05-16 Starbard Nathan T Porous polymeric particles and methods of making and using them
US20160243154A1 (en) * 2013-10-23 2016-08-25 Donald W. Jessup Hyaluronic acid formulation
CN109531857B (en) * 2019-01-02 2020-11-06 华熙生物科技股份有限公司 Preparation method of hyaluronic acid or salt particles thereof and obtained product
WO2023224577A1 (en) * 2022-05-18 2023-11-23 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising micronized human insulin

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013285A1 (en) * 1989-05-01 1990-11-15 Enzytech, Inc. Process for producing small particles of biologically active molecules
US5208998A (en) * 1991-02-25 1993-05-11 Oyler Jr James R Liquid substances freeze-drying systems and methods
IT1247472B (en) * 1991-05-31 1994-12-17 Fidia Spa PROCESS FOR THE PREPARATION OF MICROSPHERES CONTAINING BIOLOGICALLY ACTIVE COMPONENTS.
DE69332240T2 (en) * 1992-06-12 2003-04-10 Teijin Ltd., Osaka ULTRA FINE POWDER FOR INHALATION AND PRODUCTION
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
JPH08301762A (en) * 1995-05-12 1996-11-19 Teijin Ltd Agent for treatment of lung cancer
US5922253A (en) * 1995-05-18 1999-07-13 Alkermes Controlled Therapeutics, Inc. Production scale method of forming microparticles
CA2199732C (en) * 1995-07-12 2007-01-30 Hiroshi Ito Mammalian excrement treating material and process for producing the same
GB9606188D0 (en) * 1996-03-23 1996-05-29 Danbiosyst Uk Pollysaccharide microspheres for the pulmonary delivery of drugs
KR100236771B1 (en) * 1997-04-01 2000-02-01 성재갑 Sustained Release Microparticle Formulation of Drugs Using Hyaluronic Acid
JP4266399B2 (en) * 1997-12-04 2009-05-20 帝人株式会社 Pharmaceutical composition for inhalation in powder form
US6284282B1 (en) * 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
EP1165050B1 (en) * 1999-04-05 2006-03-29 Mannkind Corporation Methods for fine powder formation
SE9903236D0 (en) * 1999-09-10 1999-09-10 Astra Ab Method of obtaining microparticles

Also Published As

Publication number Publication date
ES2339423T3 (en) 2010-05-20
PT1259228E (en) 2010-04-07
ATE454136T1 (en) 2010-01-15
JP2003525232A (en) 2003-08-26
GB0004827D0 (en) 2000-04-19
US20080112896A1 (en) 2008-05-15
EP1259228B1 (en) 2010-01-06
EP1259228A1 (en) 2002-11-27
CA2401696A1 (en) 2001-09-07
DE60140997D1 (en) 2010-02-25
WO2001064188A1 (en) 2001-09-07
US20030133879A1 (en) 2003-07-17

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