AU2001235006A1 - Prophylactic and therapeutic monoclonal antibodies - Google Patents
Prophylactic and therapeutic monoclonal antibodiesInfo
- Publication number
- AU2001235006A1 AU2001235006A1 AU2001235006A AU3500601A AU2001235006A1 AU 2001235006 A1 AU2001235006 A1 AU 2001235006A1 AU 2001235006 A AU2001235006 A AU 2001235006A AU 3500601 A AU3500601 A AU 3500601A AU 2001235006 A1 AU2001235006 A1 AU 2001235006A1
- Authority
- AU
- Australia
- Prior art keywords
- monoclonal antibodies
- prophylactic
- therapeutic monoclonal
- antibodies
- mixtures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000000069 prophylactic effect Effects 0.000 title 1
- 229940126622 therapeutic monoclonal antibody Drugs 0.000 title 1
- 206010046865 Vaccinia virus infection Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 208000007089 vaccinia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
In this application are described vaccinia monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of vaccinia virus infections in vitro and in vivo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18206600P | 2000-02-11 | 2000-02-11 | |
| US60182066 | 2000-02-11 | ||
| PCT/US2001/004520 WO2001058485A2 (en) | 2000-02-11 | 2001-02-09 | Prophylactic and therapeutic antibodies against vaccina virus antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001235006A1 true AU2001235006A1 (en) | 2001-08-20 |
Family
ID=22666929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001235006A Abandoned AU2001235006A1 (en) | 2000-02-11 | 2001-02-09 | Prophylactic and therapeutic monoclonal antibodies |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6451309B2 (en) |
| EP (1) | EP1309348B1 (en) |
| AT (1) | ATE419872T1 (en) |
| AU (1) | AU2001235006A1 (en) |
| DE (1) | DE60137337D1 (en) |
| WO (1) | WO2001058485A2 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000275666A (en) * | 1999-03-25 | 2000-10-06 | Hitachi Ltd | Liquid crystal display |
| CA2482333A1 (en) * | 2002-02-11 | 2003-08-21 | Alexion Pharmaceuticals, Inc. | Human antibodies for therapy against vaccinia or smallpox |
| US6982156B2 (en) * | 2002-03-27 | 2006-01-03 | Trustees Of The University Of Pennsylvania | Compositions and methods modulating variola and vaccinia virus |
| GB0212666D0 (en) | 2002-05-31 | 2002-07-10 | Secr Defence | Immunogenic sequences |
| US20060003316A1 (en) * | 2002-07-15 | 2006-01-05 | John Simard | Immunogenic compositions derived from poxviruses and methods of using same |
| WO2004053454A2 (en) * | 2002-11-27 | 2004-06-24 | Government Of The United States Of America As Represented By The Sercretary Of The Department Of Health And Human Services National Institutes Of Health | Methods for detecting invasion of a cell |
| US20040185022A1 (en) * | 2003-02-19 | 2004-09-23 | Steven Rubin | Regimen for acne treatment |
| AU2004262506A1 (en) * | 2003-02-28 | 2005-02-17 | National Institutes Of Health | Compositions, methods and kits relating to poxvirus subunit vaccines |
| JP2007517767A (en) * | 2003-03-11 | 2007-07-05 | ダナ ファーバー キャンサー インスティテュート | Methods for inhibiting viral pathogenicity |
| US20050009110A1 (en) * | 2003-07-08 | 2005-01-13 | Xiao-Jia Chang | Methods of producing antibodies for diagnostics and therapeutics |
| EP1781826A4 (en) * | 2004-06-12 | 2009-04-29 | Univ Oregon Health & Science | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING ORTHOPOXVIRUS |
| BRPI0512235A (en) * | 2004-06-18 | 2008-02-19 | Ambrx Inc | antigen-binding polypeptides and their uses |
| RU2281327C2 (en) * | 2004-09-01 | 2006-08-10 | Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека" | STRAIN OF HYBRID CULTURING Rattus norvegicus 122H9 CELLS WHICH IS PRODUCER OF CROSS-REACTIVE NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST PATHOGENIC FOR HUMAN ORTHOPOXVIRUSES |
| US7393533B1 (en) * | 2004-11-08 | 2008-07-01 | La Jolla Institute For Allergy And Immunology | H3L envelope protein immunization methods and H3L envelope passive protection methods |
| US20090087456A1 (en) * | 2005-09-07 | 2009-04-02 | James Edward Eyles | Adjuvanted vaccine |
| US7790182B2 (en) * | 2005-09-21 | 2010-09-07 | The United States Of America As Represented By The Secretary Of The Army | Protein vaccines against poxviruses |
| EP2314619A1 (en) | 2005-12-05 | 2011-04-27 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| GB2453475B (en) | 2006-07-25 | 2011-01-19 | Secr Defence | Live vaccine strain |
| WO2008085551A2 (en) * | 2006-08-23 | 2008-07-17 | Quercegen Pharma Llc | Smallpox monoclonal antibody |
| WO2008100508A2 (en) | 2007-02-12 | 2008-08-21 | The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of The United States Army Medical Research Institute Of Infectious Diseases | Puumala virus full-length m segment-based dna vaccines |
| WO2009009039A2 (en) * | 2007-07-09 | 2009-01-15 | The Usa, As Represented By The Secretary Of The Army, On Behalf Of The United States Army Medical Research | Compositions containing full-length l1r nucleic acid and endoplasmic reticulum targeting sequence |
| RU2342951C1 (en) * | 2007-09-12 | 2009-01-10 | Федеральное государственное "48 Центральный научно-исследовательский институт Министерства обороны Российской Федерации" | Preparation containing antibody antivariolic from whey of blood of horses, solution for intramuscular introduction |
| US8795667B2 (en) * | 2007-12-19 | 2014-08-05 | Macrogenics, Inc. | Compositions for the prevention and treatment of smallpox |
| GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
| US9315826B2 (en) | 2011-01-31 | 2016-04-19 | The United States of America as rep. by the Sec'y of the Army, for U.S. Army Medical Research Institute of Infectious Diseases | Nucleic acids containing a synthetic codon-optimized Sin Nombre virus full-length M gene |
| US9861681B2 (en) | 2013-04-18 | 2018-01-09 | The United States of America as represented by the Secretary of the Army, on behalf of the United States Army Medical Research Institute of Infectious Diseases | Therapeutic compositions for neutralizing type I interferons, and methods of use |
| DE102015107577A1 (en) * | 2015-05-13 | 2016-11-17 | Osram Opto Semiconductors Gmbh | Optoelectronic semiconductor chip |
| US10381278B2 (en) * | 2017-09-14 | 2019-08-13 | Powertech Technology Inc. | Testing method of packaging process and packaging structure |
| IL300836A (en) * | 2023-02-21 | 2024-09-01 | State Of Israel Israel Institute For Biological Res | Anti–pox viruses antibodies |
| CN120665190B (en) * | 2025-08-21 | 2025-10-28 | 中国人民解放军军事科学院军事医学研究院 | Anti-orthopoxvirus neutralizing monoclonal antibody B36B9 and application thereof |
-
2001
- 2001-02-09 DE DE60137337T patent/DE60137337D1/en not_active Expired - Fee Related
- 2001-02-09 WO PCT/US2001/004520 patent/WO2001058485A2/en not_active Ceased
- 2001-02-09 US US09/781,124 patent/US6451309B2/en not_active Expired - Lifetime
- 2001-02-09 EP EP01907203A patent/EP1309348B1/en not_active Expired - Lifetime
- 2001-02-09 AU AU2001235006A patent/AU2001235006A1/en not_active Abandoned
- 2001-02-09 AT AT01907203T patent/ATE419872T1/en not_active IP Right Cessation
-
2002
- 2002-09-16 US US10/202,532 patent/US6620412B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE419872T1 (en) | 2009-01-15 |
| US6451309B2 (en) | 2002-09-17 |
| WO2001058485A3 (en) | 2002-01-10 |
| US20030022226A1 (en) | 2003-01-30 |
| WO2001058485A2 (en) | 2001-08-16 |
| US20020009447A1 (en) | 2002-01-24 |
| EP1309348A2 (en) | 2003-05-14 |
| US6620412B2 (en) | 2003-09-16 |
| EP1309348B1 (en) | 2009-01-07 |
| DE60137337D1 (en) | 2009-02-26 |
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