AU2001233925A1 - Assay for measuring holo-transcobalamin and folate - Google Patents
Assay for measuring holo-transcobalamin and folateInfo
- Publication number
- AU2001233925A1 AU2001233925A1 AU2001233925A AU3392501A AU2001233925A1 AU 2001233925 A1 AU2001233925 A1 AU 2001233925A1 AU 2001233925 A AU2001233925 A AU 2001233925A AU 3392501 A AU3392501 A AU 3392501A AU 2001233925 A1 AU2001233925 A1 AU 2001233925A1
- Authority
- AU
- Australia
- Prior art keywords
- holo
- folate
- assay
- transcobalamin
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000003556 assay Methods 0.000 title abstract 2
- 229940014144 folate Drugs 0.000 title abstract 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 title abstract 2
- 235000019152 folic acid Nutrition 0.000 title abstract 2
- 239000011724 folic acid Substances 0.000 title abstract 2
- 102000011409 Transcobalamins Human genes 0.000 abstract 2
- 108010023603 Transcobalamins Proteins 0.000 abstract 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
Abstract
An assay method comprising the detection of holotranscobalamin II (holo-TCII) and folate in a cobalamin-containing sample from a subject.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0004042 | 2000-02-21 | ||
| GBGB0004042.8A GB0004042D0 (en) | 2000-02-21 | 2000-02-21 | Assay |
| PCT/GB2001/000744 WO2001063297A1 (en) | 2000-02-21 | 2001-02-21 | Assay for measuring holo-transcobalamin and folate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001233925A1 true AU2001233925A1 (en) | 2001-09-03 |
Family
ID=9886096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001233925A Abandoned AU2001233925A1 (en) | 2000-02-21 | 2001-02-21 | Assay for measuring holo-transcobalamin and folate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030148541A1 (en) |
| EP (1) | EP1257830B1 (en) |
| JP (1) | JP2003524185A (en) |
| AT (1) | ATE360214T1 (en) |
| AU (1) | AU2001233925A1 (en) |
| CY (1) | CY1106705T1 (en) |
| DE (1) | DE60127941T2 (en) |
| DK (1) | DK1257830T3 (en) |
| ES (1) | ES2284616T3 (en) |
| GB (1) | GB0004042D0 (en) |
| PT (1) | PT1257830E (en) |
| WO (1) | WO2001063297A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2505995C (en) * | 2002-11-26 | 2012-04-17 | Axis-Shield Asa | Cobalamin assay |
| GB0305904D0 (en) * | 2003-03-14 | 2003-04-23 | Cobento Biotech Aps | Test |
| CN114206367B (en) * | 2019-08-09 | 2024-07-19 | 美国西门子医学诊断股份有限公司 | Anti-porcine TCN1 monoclonal antibodies and methods of producing and using the same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4273757A (en) * | 1977-06-02 | 1981-06-16 | Yissum Research Development Company | Determination of transcobalamins |
| US4423154A (en) * | 1978-06-26 | 1983-12-27 | Becton Dickinson And Company | Simultaneous radioassay of folate and vitamin B12 |
| US4426455A (en) * | 1980-09-22 | 1984-01-17 | Amersham International Limited | Assay of vitamin B12 |
| US4680273A (en) * | 1985-07-29 | 1987-07-14 | Victor Herbert | Assay for vitamin B12 deficiency |
| US4892710A (en) * | 1987-07-07 | 1990-01-09 | Bioprobe International, Inc. | Cartridge assembly with multi-purpose closure tubing |
| EP0367795A4 (en) * | 1987-07-16 | 1992-01-15 | E.I. Du Pont De Nemours And Company | Affinity separating using immobilized flocculating reagents |
| WO1991005063A1 (en) * | 1989-10-05 | 1991-04-18 | Exoxemis, Inc. | Haloperoxidase acid optimum chemiluminescence assay system |
| US6020209A (en) * | 1997-04-28 | 2000-02-01 | The United States Of America As Represented By The Secretary Of The Navy | Microcapillary-based flow-through immunosensor and displacement immunoassay using the same |
| AU5436499A (en) * | 1998-08-20 | 2000-03-14 | Axis Biochemicals Asa | Assay method for cardiovascular disease |
-
2000
- 2000-02-21 GB GBGB0004042.8A patent/GB0004042D0/en not_active Ceased
-
2001
- 2001-02-21 US US10/204,457 patent/US20030148541A1/en not_active Abandoned
- 2001-02-21 DE DE60127941T patent/DE60127941T2/en not_active Expired - Fee Related
- 2001-02-21 ES ES01905961T patent/ES2284616T3/en not_active Expired - Lifetime
- 2001-02-21 AT AT01905961T patent/ATE360214T1/en not_active IP Right Cessation
- 2001-02-21 AU AU2001233925A patent/AU2001233925A1/en not_active Abandoned
- 2001-02-21 JP JP2001562210A patent/JP2003524185A/en not_active Withdrawn
- 2001-02-21 PT PT01905961T patent/PT1257830E/en unknown
- 2001-02-21 DK DK01905961T patent/DK1257830T3/en active
- 2001-02-21 WO PCT/GB2001/000744 patent/WO2001063297A1/en not_active Ceased
- 2001-02-21 EP EP01905961A patent/EP1257830B1/en not_active Expired - Lifetime
-
2007
- 2007-07-05 CY CY20071100895T patent/CY1106705T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1257830B1 (en) | 2007-04-18 |
| DE60127941T2 (en) | 2008-01-17 |
| US20030148541A1 (en) | 2003-08-07 |
| ATE360214T1 (en) | 2007-05-15 |
| DK1257830T3 (en) | 2007-07-30 |
| WO2001063297A1 (en) | 2001-08-30 |
| JP2003524185A (en) | 2003-08-12 |
| EP1257830A1 (en) | 2002-11-20 |
| CY1106705T1 (en) | 2012-05-23 |
| GB0004042D0 (en) | 2000-04-12 |
| DE60127941D1 (en) | 2007-05-31 |
| PT1257830E (en) | 2007-06-08 |
| ES2284616T3 (en) | 2007-11-16 |
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