[go: up one dir, main page]

AU2001232275A1 - Novel collagen-like protein clac, precursor thereof and genes encoding the same - Google Patents

Novel collagen-like protein clac, precursor thereof and genes encoding the same

Info

Publication number
AU2001232275A1
AU2001232275A1 AU2001232275A AU3227501A AU2001232275A1 AU 2001232275 A1 AU2001232275 A1 AU 2001232275A1 AU 2001232275 A AU2001232275 A AU 2001232275A AU 3227501 A AU3227501 A AU 3227501A AU 2001232275 A1 AU2001232275 A1 AU 2001232275A1
Authority
AU
Australia
Prior art keywords
same
clac
precursor
genes encoding
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001232275A
Inventor
Tadafumi Hashimoto
Takeshi Iwatsubo
Yasuo Nagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BF Research Institute Inc
Original Assignee
BF Research Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BF Research Institute Inc filed Critical BF Research Institute Inc
Publication of AU2001232275A1 publication Critical patent/AU2001232275A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A novel human collagen-like protein CLAC occurring in brain amyloid and its precursor CLAC-P; genes encoding the same; cDNA of mouse CLAC-P and its deduced amino acid sequence; antibodies specific to these proteins; and methods of diagnosing treating and preventing Alzheimer's disease by using the same.
AU2001232275A 2000-02-14 2001-02-14 Novel collagen-like protein clac, precursor thereof and genes encoding the same Abandoned AU2001232275A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOJP00/00788 2000-02-14
JP0000788 2000-02-14
PCT/JP2001/001014 WO2001058943A1 (en) 2000-02-14 2001-02-14 Novel collagen-like protein clac, precursor thereof and genes encoding the same

Publications (1)

Publication Number Publication Date
AU2001232275A1 true AU2001232275A1 (en) 2001-08-20

Family

ID=11735679

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001232275A Abandoned AU2001232275A1 (en) 2000-02-14 2001-02-14 Novel collagen-like protein clac, precursor thereof and genes encoding the same

Country Status (9)

Country Link
US (4) US7514542B2 (en)
EP (1) EP1270588B1 (en)
JP (1) JP4249927B2 (en)
CN (1) CN1241940C (en)
AT (1) ATE490979T1 (en)
AU (1) AU2001232275A1 (en)
CA (1) CA2400117C (en)
DE (1) DE60143608D1 (en)
WO (1) WO2001058943A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1288226A1 (en) * 2001-09-03 2003-03-05 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Modification of the expression levels of Toll-like receptor familiy members for influencing neurodegeneration and neuroprotection in the human central nervous system
AU2003218208A1 (en) * 2002-03-19 2003-10-08 Children's Medical Center Corporation Methods for diagnosis and prognosis of cancer
JP2005073592A (en) * 2003-09-01 2005-03-24 Yukiguni Maitake Co Ltd Gene encoding lectin derived from grifola frondosa
CN103772560B (en) * 2012-10-22 2017-03-01 中国石油化工股份有限公司 A kind of fiber polyvinyl resin with super-high molecular weight and preparation method thereof
US9234757B2 (en) * 2013-11-29 2016-01-12 Fedex Corporate Services, Inc. Determining node location using a variable power characteristic of a node in a wireless node network
KR101873247B1 (en) * 2016-08-22 2018-08-02 대한민국 Potential autoantibody biomarkers for the detection and diagnosis of dementia
CA3070446A1 (en) 2017-07-25 2019-01-31 Immutics, Inc. Treating cancer by blocking the interaction of tim-3 and its ligand
US11180541B2 (en) * 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
CN108061795B (en) * 2017-11-24 2020-02-18 大连医科大学 Western blotting for improved detection sensitivity
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
KR20230016186A (en) 2020-05-26 2023-02-01 트루바인딩 아이엔씨. Method for treating inflammatory diseases by galectic-3 blockade

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2311201A1 (en) * 1999-08-05 2001-02-05 Genset S.A. Ests and encoded human proteins

Also Published As

Publication number Publication date
US7888076B2 (en) 2011-02-15
US8173775B2 (en) 2012-05-08
CA2400117A1 (en) 2001-08-16
CA2400117C (en) 2009-11-17
CN1422280A (en) 2003-06-04
US20090280530A1 (en) 2009-11-12
WO2001058943A1 (en) 2001-08-16
JP4249927B2 (en) 2009-04-08
EP1270588B1 (en) 2010-12-08
US20040250304A1 (en) 2004-12-09
ATE490979T1 (en) 2010-12-15
US20110137013A1 (en) 2011-06-09
DE60143608D1 (en) 2011-01-20
EP1270588A4 (en) 2003-07-30
EP1270588A1 (en) 2003-01-02
US20100004433A1 (en) 2010-01-07
CN1241940C (en) 2006-02-15
US7514542B2 (en) 2009-04-07

Similar Documents

Publication Publication Date Title
WO2005061545A3 (en) Nogoa antibodies for the treatment of alzheimer disease
AT500379B8 (en) TAU PROTEINS
ATE466883T1 (en) CATALYTIC MONOCLONAL ANTIBODIES WITH PROTEASE ACTIVITY FOR SELECTIVE LYSIS OF THE PROTEIN COMPONENT OF PLAQUES AND AGGREGATES ASSOCIATED WITH PATHOLOGICAL CONDITIONS
DE50210317D1 (en) PEPTIDE FOR DIAGNOSIS AND THERAPY OF ALZHEIMER DEMENZ
EP1361229A3 (en) Use of Tyrosine Kinase (PYK2) to produce antibodies
AU2002328429A1 (en) CONSTRUCTION OF ANTIBODY USING MRL/lpr MOUSE
AU2001232275A1 (en) Novel collagen-like protein clac, precursor thereof and genes encoding the same
WO2002012284A3 (en) Iron regulating protein-2 (irp-2) as a diagnostic for neurodegenerative disease
SG121733A1 (en) Nucleic acid molecules polypeptides and uses therefor, including diagnosis and treatment of alzheimer's disease
DK0966533T3 (en) Activity-dependent neurotrophic factor III (ADNF III).
WO2000015659A3 (en) Stomach polypeptide zsig28
GEP20043386B (en) β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same
AU4316600A (en) Human brain carboxypeptidase b
EE200000478A (en) Peptide, gene encoding it, diagnostic reagent and diagnostic kit, for use in the treatment of rickettsia
ATE401402T1 (en) PROTEINS INTERACTING WITH SYNDEKAN AND THEIR USE
WO2002088378A3 (en) 66784, a novel human potassium channel and uses therefor
WO2001012788A3 (en) Tryptase-like polypeptide ztryp1
WO2003000717A3 (en) Identification of ses-3 (spr-5) in c. elegans and the uses of the same
WO2003000889A3 (en) Identification of ses-1 and the uses of the same
CA2351722A1 (en) Mast cell-specific signal transducer and cdna thereof
WO2001075008A3 (en) A novel polypeptide - human helix-loop-helix protein 11 and a polynucleotide encoding the same
WO2001085903A3 (en) A novel polypeptide- human protein 9 which contains a p5cr characteristic sequence fragment and a polynucleotide encoding the same
WO2002070560A3 (en) Nuclear hormone receptor ligand binding domain
SE0101317D0 (en) Protein cluster v
WO2003040394A3 (en) Production of recombinant proteins in vivo and use for generating antibodies