AU2001228625A1 - Composition of antigen and glycolipid adjuvant sublingual administration - Google Patents
Composition of antigen and glycolipid adjuvant sublingual administrationInfo
- Publication number
- AU2001228625A1 AU2001228625A1 AU2001228625A AU2862501A AU2001228625A1 AU 2001228625 A1 AU2001228625 A1 AU 2001228625A1 AU 2001228625 A AU2001228625 A AU 2001228625A AU 2862501 A AU2862501 A AU 2862501A AU 2001228625 A1 AU2001228625 A1 AU 2001228625A1
- Authority
- AU
- Australia
- Prior art keywords
- antigen
- composition
- sublingual administration
- glycolipid adjuvant
- glycolipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 title 1
- 229930186217 Glycolipid Natural products 0.000 title 1
- 239000002671 adjuvant Substances 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0000891 | 2000-01-14 | ||
| GBGB0000891.2A GB0000891D0 (en) | 2000-01-14 | 2000-01-14 | Formulation |
| PCT/GB2001/000142 WO2001051082A1 (en) | 2000-01-14 | 2001-01-15 | Composition of antigen and glycolipid adjuvant sublingual administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001228625A1 true AU2001228625A1 (en) | 2001-07-24 |
Family
ID=9883730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001228625A Abandoned AU2001228625A1 (en) | 2000-01-14 | 2001-01-15 | Composition of antigen and glycolipid adjuvant sublingual administration |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8470331B2 (en) |
| EP (3) | EP2322212A1 (en) |
| JP (1) | JP4648603B2 (en) |
| AR (1) | AR027924A1 (en) |
| AU (1) | AU2001228625A1 (en) |
| CA (1) | CA2397359C (en) |
| CZ (1) | CZ304941B6 (en) |
| DE (1) | DE60139305D1 (en) |
| DK (1) | DK2100616T3 (en) |
| ES (2) | ES2328336T5 (en) |
| GB (2) | GB0000891D0 (en) |
| HU (1) | HU230545B1 (en) |
| PL (1) | PL356963A1 (en) |
| SK (1) | SK288411B6 (en) |
| WO (1) | WO2001051082A1 (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060025726A1 (en) * | 1996-06-04 | 2006-02-02 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with pharmacologically active layer |
| US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
| US20060030826A1 (en) * | 1996-06-04 | 2006-02-09 | Vance Products Incorporated,d/b/a Cook Urological Incorporated | Implantable medical device with anti-neoplastic drug |
| GB9706957D0 (en) * | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| WO2004047793A1 (en) | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Pharmaceutical allergen product |
| US8012505B2 (en) | 2003-02-28 | 2011-09-06 | Alk-Abello A/S | Dosage form having a saccharide matrix |
| WO2005115449A1 (en) * | 2004-05-28 | 2005-12-08 | Alk-Abelló A/S | Method of treating allergy and infection by eliciting an iga antibody response |
| ITMI20061117A1 (en) * | 2006-06-09 | 2007-12-10 | Michele Bonanomi | A PHARMACEUTICAL COMPOSITION FOR THE SUBLINGUAL ADMINISTRATION OF VACCINI METHOD FOR ITS PREPARATION AND USES |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| PT2484375T (en) | 2006-09-26 | 2018-07-09 | Infectious Disease Res Inst | Vaccine composition containing synthetic adjuvant |
| EP2425242B1 (en) | 2009-04-29 | 2019-06-05 | Pravin K. Muniyappa | Device and method for the diagnosis of gastrointestinal allergy |
| US8722064B2 (en) | 2009-06-05 | 2014-05-13 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| GB201009273D0 (en) * | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
| AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| JP5650780B2 (en) | 2012-04-04 | 2015-01-07 | 日東電工株式会社 | Vaccine composition |
| SG11201407586WA (en) | 2012-05-16 | 2014-12-30 | Immune Design Corp | Vaccines for hsv-2 |
| HK1214510A1 (en) | 2013-04-18 | 2016-07-29 | Immune Design Corp. | Gla monotherapy for use in cancer treatment |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| TW201709926A (en) * | 2015-04-23 | 2017-03-16 | 賽諾菲公司 | Glucopyranosyl lipid A and allergen formulations for sublingual administration |
| WO2017173398A1 (en) | 2016-04-01 | 2017-10-05 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
| KR102151962B1 (en) | 2020-03-24 | 2020-09-04 | 안병철 | Method for producing serum composition for preventing or treating infectious disease in young mammal, serum composition produced by the same method, and uses thereof |
| WO2021194038A1 (en) * | 2020-03-24 | 2021-09-30 | 안병철 | Method for producing serum composition for preventing or treating mucosa-related infectious disease in young mammals, serum composition produced thereby, and use thereof |
Family Cites Families (53)
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| GB1128637A (en) | 1966-09-13 | 1968-09-25 | Beecham Group Ltd | Influenza vaccine |
| US3541201A (en) | 1968-12-18 | 1970-11-17 | Ethan Alan Brown | Novel sodium chloride encapsulated injectionable substances |
| GB1377074A (en) | 1971-07-13 | 1974-12-11 | Beecham Group Ltd | Process for preparing injectable compositions |
| GB1492973A (en) | 1974-02-16 | 1977-11-23 | Beecham Group Ltd | Process for preparing injectable compositions |
| US4070455A (en) * | 1974-02-16 | 1978-01-24 | Beecham Group Limited | Process for preparing injectable desensitizing compositions and products thereof in microparticle form |
| EP0182442B2 (en) | 1978-12-22 | 1996-04-03 | Biogen, Inc. | Recombinant DNA molecules and their method of production |
| US4258029A (en) * | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4987237A (en) | 1983-08-26 | 1991-01-22 | Ribi Immunochem Research, Inc. | Derivatives of monophosphoryl lipid A |
| DE3521994A1 (en) * | 1985-06-20 | 1987-01-02 | Bayer Ag | N- (2-AMINOACYLAMIDO-2-DESOXY-HEXOSYL) -AMIDES, CARBAMATES AND UREAS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5244663A (en) * | 1987-01-28 | 1993-09-14 | Medibrevex | Therapeutic method against allergy |
| US4975420A (en) * | 1987-09-30 | 1990-12-04 | University Of Saskatchewan | Agents and procedures for provoking an immune response to GnRH and immuno sterilizing mammals |
| FR2621916B1 (en) * | 1987-10-19 | 1990-03-09 | Bioeurope | WATER-SOLUBLE L-TYROSINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| GB9106048D0 (en) | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccines |
| CA2131442A1 (en) | 1992-03-03 | 1993-09-04 | Seishi Tsuchiya | Oral vaccine |
| UA40597C2 (en) * | 1992-06-25 | 2001-08-15 | Смітклайн Бічем Байолоджікалс С.А. | Vaccine composition, method for treatment of mammals, diseased or receptive to the infection, method for treatment of mammals with cancer, method for production of vaccine composition, composition of adjuvants |
| CN1120310A (en) | 1993-03-11 | 1996-04-10 | 塞科雷泰克公司 | Polymeric mucoadhesives in the delivery of immunogens at mucosal surfaces |
| CN1087176C (en) * | 1993-03-23 | 2002-07-10 | 史密斯克莱·比奇曼生物公司 | Vaccine preparations containing 3-O deacylated monophosphoryl lipid A |
| DE69426077T3 (en) | 1993-05-25 | 2004-09-02 | Wyeth Holdings Corp. | ADJUVANTS FOR VACCINE AGAINST THE RESPIRATORY SYNCITIAL VIRUS |
| WO1995005850A1 (en) * | 1993-08-27 | 1995-03-02 | Enteric Research Laboratories, Inc. | Campylobacter jejuni antigens, and methods for their production and use |
| GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
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| US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
| US5646115A (en) * | 1994-10-07 | 1997-07-08 | Heska Corporation | Ectoparasite saliva proteins and apparatus to collect such proteins |
| WO1996025664A1 (en) | 1995-02-17 | 1996-08-22 | Immunotherapy, Inc. | Immunotherapy screening, prognosis, and treatment methods and compositions |
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| DE69835424T2 (en) * | 1997-03-10 | 2007-02-08 | Immtech Biologics, LLC, Bucyrus | BOVINE BREATHING AND DARM CORONAVIRUS AS VACCINE |
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| WO1998058956A2 (en) * | 1997-06-23 | 1998-12-30 | Ludwig Institute For Cancer Research | Methods for inducing an immune response involving prime-boost protocols |
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| GB9720585D0 (en) | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
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| AU4563099A (en) * | 1998-06-11 | 1999-12-30 | Trustees Of The University Of Pennsylvania, The | Methods and compositions for delivering proteins to macrophage cells and cells of macrophage derived lineage |
| CA2330209A1 (en) | 1998-06-12 | 1999-12-23 | Smithkline Beecham Biologicals S.A. | Recombinant production of toxoplasma sag1 antigen |
| AU4376199A (en) * | 1998-06-26 | 2000-01-17 | Pasteur Merieux Serums Et Vaccins | Mucosal targeting immunisation |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| US6734172B2 (en) * | 1998-11-18 | 2004-05-11 | Pacific Northwest Research Institute | Surface receptor antigen vaccines |
| PT1031347E (en) * | 1999-01-27 | 2002-09-30 | Idea Ag | TRANSNATIONAL TRANSMISSION / IMMUNIZATION WITH MOST ADAPTABLE VEHICLES |
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| GB9909077D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
| IL145786A0 (en) | 1999-04-23 | 2002-07-25 | M & E Biotech As | Method for down-regulating il5 activity |
| UA81216C2 (en) * | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
| WO2000076476A1 (en) | 1999-06-11 | 2000-12-21 | Endorex Corporation | Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination |
| GB9924529D0 (en) * | 1999-10-15 | 1999-12-15 | Smithkline Beecham Biolog | Novel compounds |
| DE60123603T2 (en) * | 2000-06-14 | 2007-08-16 | William Leslie Diss Porter | LIPID TO CHANGE THE DEFENSE SYSTEM |
| GB0020089D0 (en) | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
-
2000
- 2000-01-14 GB GBGB0000891.2A patent/GB0000891D0/en active Pending
-
2001
- 2001-01-12 AR ARP010100157A patent/AR027924A1/en unknown
- 2001-01-15 US US10/181,684 patent/US8470331B2/en not_active Expired - Fee Related
- 2001-01-15 WO PCT/GB2001/000142 patent/WO2001051082A1/en not_active Ceased
- 2001-01-15 ES ES01942305.2T patent/ES2328336T5/en not_active Expired - Lifetime
- 2001-01-15 DK DK09159908.4T patent/DK2100616T3/en active
- 2001-01-15 AU AU2001228625A patent/AU2001228625A1/en not_active Abandoned
- 2001-01-15 ES ES09159908.4T patent/ES2561360T3/en not_active Expired - Lifetime
- 2001-01-15 HU HU0203972A patent/HU230545B1/en unknown
- 2001-01-15 GB GB0101035A patent/GB2360210B/en not_active Expired - Lifetime
- 2001-01-15 CZ CZ2002-2417A patent/CZ304941B6/en not_active IP Right Cessation
- 2001-01-15 CA CA2397359A patent/CA2397359C/en not_active Expired - Lifetime
- 2001-01-15 JP JP2001551505A patent/JP4648603B2/en not_active Expired - Fee Related
- 2001-01-15 PL PL01356963A patent/PL356963A1/en unknown
- 2001-01-15 EP EP10011044A patent/EP2322212A1/en not_active Withdrawn
- 2001-01-15 SK SK1041-2002A patent/SK288411B6/en not_active IP Right Cessation
- 2001-01-15 EP EP01942305.2A patent/EP1255563B2/en not_active Expired - Lifetime
- 2001-01-15 EP EP09159908.4A patent/EP2100616B1/en not_active Expired - Lifetime
- 2001-01-15 DE DE60139305T patent/DE60139305D1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2328336T5 (en) | 2016-06-21 |
| GB0101035D0 (en) | 2001-02-28 |
| HU230545B1 (en) | 2016-11-28 |
| DK2100616T3 (en) | 2016-02-08 |
| ES2328336T3 (en) | 2009-11-12 |
| EP1255563B1 (en) | 2009-07-22 |
| ES2561360T3 (en) | 2016-02-25 |
| HUP0203972A3 (en) | 2011-02-28 |
| AR027924A1 (en) | 2003-04-16 |
| US20030165512A1 (en) | 2003-09-04 |
| CZ304941B6 (en) | 2015-02-04 |
| HUP0203972A2 (en) | 2003-03-28 |
| EP1255563A1 (en) | 2002-11-13 |
| SK288411B6 (en) | 2016-10-03 |
| JP4648603B2 (en) | 2011-03-09 |
| CZ20022417A3 (en) | 2003-03-12 |
| US8470331B2 (en) | 2013-06-25 |
| EP1255563B2 (en) | 2016-03-02 |
| DE60139305D1 (en) | 2009-09-03 |
| CA2397359C (en) | 2012-06-05 |
| EP2322212A1 (en) | 2011-05-18 |
| SK10412002A3 (en) | 2003-05-02 |
| PL356963A1 (en) | 2004-07-12 |
| GB0000891D0 (en) | 2000-03-08 |
| WO2001051082A1 (en) | 2001-07-19 |
| JP2003519669A (en) | 2003-06-24 |
| EP2100616A2 (en) | 2009-09-16 |
| EP2100616A3 (en) | 2009-09-23 |
| GB2360210A (en) | 2001-09-19 |
| CA2397359A1 (en) | 2001-07-19 |
| EP2100616B1 (en) | 2015-11-25 |
| GB2360210B (en) | 2004-12-15 |
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