AU2001218866A1 - Preparation for strengthening the immune response in the waldeyer's ring and theoronasal mucosa by intranasal administration - Google Patents
Preparation for strengthening the immune response in the waldeyer's ring and theoronasal mucosa by intranasal administrationInfo
- Publication number
- AU2001218866A1 AU2001218866A1 AU2001218866A AU1886601A AU2001218866A1 AU 2001218866 A1 AU2001218866 A1 AU 2001218866A1 AU 2001218866 A AU2001218866 A AU 2001218866A AU 1886601 A AU1886601 A AU 1886601A AU 2001218866 A1 AU2001218866 A1 AU 2001218866A1
- Authority
- AU
- Australia
- Prior art keywords
- waldeyer
- strengthening
- ring
- mucosa
- glucan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000005728 strengthening Methods 0.000 title abstract 4
- 210000004877 mucosa Anatomy 0.000 title abstract 3
- 230000028993 immune response Effects 0.000 title abstract 2
- 229920001503 Glucan Polymers 0.000 abstract 5
- 230000000887 hydrating effect Effects 0.000 abstract 2
- 230000001969 hypertrophic effect Effects 0.000 abstract 2
- 230000002757 inflammatory effect Effects 0.000 abstract 2
- 230000001154 acute effect Effects 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 210000002850 nasal mucosa Anatomy 0.000 abstract 1
- 210000001331 nose Anatomy 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A product to be administered by nose for preventing inflammatory or hypertrophic forms and strengthening the immune action in the Waldeyer's ring and the oronasal mucosa consists of a physiological action with a high concentration in a polysaccharide such as glucan. In particular, two solutions having different concentrations have been specified, namely a first physiological solution with a glucan concentration equal to 0.25 % for cleaning the nasal fossae and with a preventive hydrating, reepithelializing capability of strengthening the immune action in the Waldeyer's ring and the oronasal mucosa, and a physiological solution with a glucan concentration equal to 2 % for hydrating and reepithelializing the nasal mucosa, capable of strengthening the immune response in the Waldeyer's ring duringthe acute phase of the inflammatory, hypertrophic forms of the same. Glucan is preferably used in the form beta -(1-3)-glucan.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IT2000/000479 WO2002041900A1 (en) | 2000-11-22 | 2000-11-22 | Preparation for strengthening the immune response in the waldeyer's ring and the oronasal mucosa by intranasal administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001218866A1 true AU2001218866A1 (en) | 2002-06-03 |
Family
ID=11133585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001218866A Abandoned AU2001218866A1 (en) | 2000-11-22 | 2000-11-22 | Preparation for strengthening the immune response in the waldeyer's ring and theoronasal mucosa by intranasal administration |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1337260B1 (en) |
| AT (1) | ATE290873T1 (en) |
| AU (1) | AU2001218866A1 (en) |
| DE (1) | DE60018812T2 (en) |
| ES (1) | ES2237477T3 (en) |
| PT (1) | PT1337260E (en) |
| WO (1) | WO2002041900A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0225502D0 (en) * | 2002-11-01 | 2002-12-11 | Zoolife Internat Ltd | Therapeutic and prophylactic preparations |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0045718A3 (en) * | 1980-07-25 | 1983-01-19 | Ciba-Geigy Ag | Nasal compositions and method of preparing them |
| US4739046A (en) * | 1985-08-19 | 1988-04-19 | Luzio Nicholas R Di | Soluble phosphorylated glucan |
| US5519009A (en) * | 1993-10-01 | 1996-05-21 | Donzis; Byron A. | Solubilized yeast glucan |
| FR2780285B1 (en) * | 1998-06-29 | 2001-10-05 | Goemar Lab Sa | USE OF ISOOSMOTIC SALINE SOLUTIONS, THEIR PREPARATION METHOD AND ANTI-INFLAMMATORY DRUGS BASED ON SUCH SOLUTIONS |
-
2000
- 2000-11-22 AU AU2001218866A patent/AU2001218866A1/en not_active Abandoned
- 2000-11-22 PT PT00981644T patent/PT1337260E/en unknown
- 2000-11-22 DE DE60018812T patent/DE60018812T2/en not_active Expired - Lifetime
- 2000-11-22 EP EP00981644A patent/EP1337260B1/en not_active Expired - Lifetime
- 2000-11-22 WO PCT/IT2000/000479 patent/WO2002041900A1/en not_active Ceased
- 2000-11-22 ES ES00981644T patent/ES2237477T3/en not_active Expired - Lifetime
- 2000-11-22 AT AT00981644T patent/ATE290873T1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1337260E (en) | 2005-05-31 |
| EP1337260B1 (en) | 2005-03-16 |
| DE60018812T2 (en) | 2005-08-11 |
| DE60018812D1 (en) | 2005-04-21 |
| EP1337260A1 (en) | 2003-08-27 |
| WO2002041900A1 (en) | 2002-05-30 |
| ES2237477T3 (en) | 2005-08-01 |
| ATE290873T1 (en) | 2005-04-15 |
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